Protein and mRNA noise are inversely correlated with abundance. by Roy D. Dar (816541)

Inhibition of <i>in vitro</i> and <i>in vivo</i> inflammatory responses in rats by p30A peptide. by Jérôme Rambert (46851)

“…(D) Histopathologic analysis confirm p30A ability to decrease all components of AIA lesions: pannus formation and inflammation of the synovium (P), deformity of joint and bones (asterix), bone remodeling and destruction (arrowhead), bone neoformation (arrows) and cartilage destruction.…”

Generation of CYP5122A1 half knock-outs. by Smriti Verma (204089)

“…<b>D:</b> Western blot analysis of cell lysates from WT and HKO parasites probed with anti-CYP5122A1 antibody showing decreased level of CYP5122A1 protein in the HKO parasites. …”

Release of HIV Gag VLPs or full HIV Virions with NL4.3 backbone were not affected on tagged CHMP4B co-expression. by Shilpa Gupta (5785598)

Trichopsistides A and B: Two Highly Oxygenated Pentacyclic Polyketides with Promising Inhibitory Effects on the NF-κB Signaling Pathway from the Fungus <i>Trichoderma koningiopsis<... by Li Feng (77923)

“…Two highly oxygenated pentacyclic polyketides with two new carbon skeletons, trichopsistide A (<b>1</b>) and trichopsistide B (<b>2</b>), were isolated from the plant endophyte <i>Trichoderma koningiopsis</i> WZ-196 derived from the leaf of <i>Rubia podantha</i> Diels. …”

Effects of Cyr61 and Wnt5a on regenerating vasculature and musculature. by Devon C. Snow-Lisy (798898)

“…Scale bar, 50 μm. (Unseeded, MSC and MSC/CD34⁺ HSPC images shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0138643#pone.0138643.s001" target="_blank">S1 Fig</a>).…”

Table_1_Guanidine acetic acid exhibited greater growth performance in younger (13–30 kg) than in older (30–50 kg) lambs under high-concentrate feedlotting pattern.docx by Wen-Juan Li (1444948)

“…In a brief, the results obtained in the present study suggested that GAA (UGAA and CGAA; 1 g/kg DM) could be applied to improve growth performance in younger (13–30 kg) instead of older (30–50 kg) lambs in high-concentrate feedlotting practice.…”

Discovery of PMSA Derivative <b>11</b> as a Novel Lead Compound for Therapeutic Treatment of Osteoporosis <i>In Vitro</i> and <i>In Vivo</i> by Zhihao Chen (513264)

“…Additionally, <b>11</b> blocked the formation of F-action belts and bone resorption in a concentration-dependent manner. Mechanistically, <b>11</b> decreased the expression of genes required for osteoclastogenesis by blocking NFATc1 translocation from the cytoplasm to nucleus. …”

Penidaleodiolides A and B, Cage-Like Polyketides with Neurotransmission-Regulating Activity from the Soil Fungus <i>Penicillium daleae</i> L3SO by Qing-Yuan Wang (11571890)

“…The hypothetical biosynthetic pathways for <b>1</b> and <b>2</b> were postulated and were supported by CRISPR/Cas9 genome editing results. Penidaleodiolide A (<b>1</b>) showed a significant inhibitory effect on the action potentials of murine hippocampal basket neurons and decreased the frequency of spontaneous excitatory postsynaptic currents in a concentration-dependent manner (the inhibition ratios were 0.30 ± 0.02 for 1 μM, 0.37 ± 0.03 for 10 μM, and 0.50 ± 0.07 for 20 μM) while being devoid of cytotoxicity against the nerve cells.…”

Dietary or gavaged TU-100 and the ginger component decrease enteropooling stimulated by anti-CD3 antibody treatment in specified pathogen free (SPF) and germ free (GF) C57Bl6 mice. by Nobuhiro Ueno (346397)

Knockdown of CRT suppressed VEGF-A expression and mRNA stability through ARE in AGS cells. by Po-Chu Lee (438366)

“…VEGF-A mRNA was significantly less stable in the CRT-knockdown cells with lower half-life and 50% mRNA remaining time. …”

Practical applications of the staining method. by Shoko Sawano (3332691)

“…Our one-step staining method succeeded in verifying the decrease in MyHC2B fibers and the increase in MyHC2X fibers in the plantaris muscles of fish oil-fed rats compared with soybean oil-fed rats. …”

Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2 by Marta E. Capala (652765)

“…Downregulation of SAM50 also impaired the proliferation and replating capacity of BCR-ABL-expressing cells, again associated with a decreased mitochondrial membrane potential. …”

Effects of ROCK inhibitors H-1152 and Y-27632 on TNF-induced MLC phosphorylation, actin and CL5 reorganization and the fall in TEER. by Paul R. Clark (714064)

Analysis of Research Activity in Gastroenterology: Pancreatitis Is in Real Danger - Fig 2 by Andrea Szentesi (3239193)

Analysis of requirement for MYPT1 expression in TNF-induced MLC phosphorylation and leak. by Paul R. Clark (714064)

Preparation and characterization of chemically synthesized polyaniline–polystyrene blends as a carbon dioxide gas sensor by J., Bhadra

“…The SEM results of the above polymerized blends reflect the formation of spherical nanoparticles with diameter ranging from 50nm to 90nm with a decrease in PS concentration that facilitates the formation of clusters. …”
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Effects of the selective TrkA agonist gambogic amide on pigmentation and growth of human hair follicles <i>in vitro</i> - Fig 4 by Remo Campiche (3714208)

“…Hair follicles treated with lower concentrations of Gambogic Amide kept their anagen-like appearance. Bars = 50 μm. <b>E: Immunohistochemical quantification of melanocytes with p16, a marker for mature and senescent melanocytes</b>. …”

Box plot displaying the distributions of the deconvolution derived proportions of cell types. by Arttu Autio-Kimura (20454681)

Fig 3 - by Belinda Kweka (9931483)

“…Compared to those without G6PD deficiency, heterozygous females had decreased odds of PD/DM diagnosis (adjusted OR 0.47, 95% CI: 0.22, 0.99, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0244782#pone.0244782.t003" target="_blank">Table 3</a>). …”