Synthesis and Characterization of the Electronic and Electrochemical Properties of Thienylenevinylene Oligomers with Multinanometer Dimensions by Isabelle Jestin (3004209)

“…Thus, the 16-mer can be charged up to the hexacationic state within a 0.60-V potential window. A plot of the potential of the various redox steps vs 1/Cn suggests full coalescence into a single-step process for the 20−22-mer. …”

Image_1_EGTA Can Inhibit Vesicular Release in the Nanodomain of Single Ca2+ Channels.JPEG by Yukihiro Nakamura (735502)

“…In proximity to a channel, the vesicular sensor is often saturated for a long voltage step, but not for a brief Ca²⁺ influx typically evoked by an action potential. …”

Transcriptional and Proteomic Analysis of the <em>Aspergillus fumigatus ΔprtT</em> Protease-Deficient Mutant by Shelly Hagag (171495)

“…Penetration of the pulmonary epithelium is a key step in the infectious process. <em>A. fumigatus</em> produces extracellular proteases to degrade the host structural barriers. …”

Single neuron preferences. by Simon Nougaret (17980269)

“…(C) Average response for each run of 3 subpopulations of neurons: all the neurons that respond to the appearance of the scene (left), and among these, neurons that prefer the first run with an increase in firing rate (center), and neurons that prefer the first run with a decrease in firing rate (right). Neural activity is aligned to the presentation of the scene (start of the Delay epoch), binned in a 200-ms window with a 25-ms step between each point, and normalized for each neuron by subtracting the mean activity and dividing by the standard deviation both calculated in a baseline period (−400 ms until the appearance of the scene). n = number of neurons. …”

Kinases are recruited to the signaling complex by alternative N-t localization domains. by Paloma M. Sato (672126)

“…In most cases, mutations that disrupt specific recruitment interactions decrease pathway activation between 40%–50%. MUT Ste20[N]-Ste50[C] might still localize to the signaling complex, as Ste50's RA domain binds Cdc42 independently of Ste20's PBD domain <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002012#pbio.1002012-Truckses1" target="_blank">[53]</a>. …”

CRT silencing improved FZD-induced injury of mitochondria and cardiomyocytes. by Ming Zhang (9736)

“…When transfected NRCMs were stimulated with 50 µM FZD for 24 h, real-time PCR revealed that CRT silencing significantly inhibited the decrease of MnSOD mRNA expression (E), and western blot was used to determine the protein levels of CRT, phosphorylated and total STAT3, and MnSOD in the whole cell lysates. β-actin was used as a loading control. …”

Evolution of active membrane properties over time in iPSC-derived neurons plated on POL. by Deborah Prè (5659969)

“…<p>A) Representative traces of voltage clamp recordings showing fast inward currents followed by long-lasting outward currents in a cell at day 55, due to voltage steps in 10 mV increments (shown in the upper panel). …”

Map of thermal risk variation, based on the response of lizards to dehydration for <i>Loxopholis percarinatum</i> across the amazon basin. by Agustín Camacho (331354)

“…D represents thermal risk after a 50% decrease in rainfall, E shows risk after a decrease of 20% in tree cover, and F shows the risk for lizards with VTmax = 28.8°C, The median VTmax for <i>L</i>. …”

Presentation_2_Transcriptional Regulation of Stearoyl-Acyl Carrier Protein Desaturase Genes in Response to Abiotic Stresses Leads to Changes in the Unsaturated Fatty Acids Composit... by M. Luisa Hernández (60159)

“…In addition, darkness caused the down-regulation of SAD genes transcripts, together with a decrease in the UFA content of chloroplast lipids. …”

Two Glycosylation Sites in H5N1 Influenza Virus Hemagglutinin That Affect Binding Preference by Computer-Based Analysis by Wentian Chen (125316)

“…The binding of hemagglutinin (HA) on the viral surface to host sialic acid (SA) receptors is a requisite step in the infection process. Phylogenetic analysis reveals that H5N1 viruses can be divided into 10 clades based on their HA sequences, with most human IVs centered from clade 1 and clade 2.1 to clade 2.3. …”

Presentation_1_Randomized Controlled Trial of Modified Nasobiliary Fixation and Drainage Technique.PPTX by Na Mi (1592458)

“…The modified “tube-nose-ear” three-step technique was performed after surgery. The clinical efficacy of a modified nasobiliary fixation and drainage technique was evaluated and compared between the test group and the control group.…”

Presentation_1_Transcriptional Regulation of Stearoyl-Acyl Carrier Protein Desaturase Genes in Response to Abiotic Stresses Leads to Changes in the Unsaturated Fatty Acids Composit... by M. Luisa Hernández (60159)

“…In addition, darkness caused the down-regulation of SAD genes transcripts, together with a decrease in the UFA content of chloroplast lipids. …”

Use of GPCR-HIT to show effect of AT₁ receptor activation on CCR2/Gα_i1 proximity. by Mohammed Akli Ayoub (176430)

“…It has been observed previously [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119803#pone.0119803.ref039" target="_blank">39</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119803#pone.0119803.ref041" target="_blank">41</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119803#pone.0119803.ref042" target="_blank">42</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0119803#pone.0119803.ref044" target="_blank">44</a>] that the BRET signal can increase or decrease as a consequence of the ligand-induced conformational change associated with Gα_i1 protein activation (A). …”

Revealing Cooperation between Knotted Conformation and Dimerization in Protein Stabilization by Molecular Dynamics Simulations by Yan Xu (14594)

“…In addition to the knotted conformation, dimerization further improves the protein stability by restricting the α1−α5 separation, which is defined as a leading step for protein unfolding. These results provide important insights into the structure–function relationship of dimerization in knotted proteins.…”

Revealing Cooperation between Knotted Conformation and Dimerization in Protein Stabilization by Molecular Dynamics Simulations by Yan Xu (14594)

“…In addition to the knotted conformation, dimerization further improves the protein stability by restricting the α1−α5 separation, which is defined as a leading step for protein unfolding. These results provide important insights into the structure–function relationship of dimerization in knotted proteins.…”

Intermolecular Failure of L-type Ca²⁺ Channel and Ryanodine Receptor Signaling in Hypertrophy by Ming Xu (151206)

“…<div><p>Pressure overload–induced hypertrophy is a key step leading to heart failure. The Ca²⁺-induced Ca²⁺ release (CICR) process that governs cardiac contractility is defective in hypertrophy/heart failure, but the molecular mechanisms remain elusive. …”

Table 1_Role of seed priming using natural biostimulants in reducing salt stress effects by reshaping physio-biochemical and antioxidant defense systems in glycine max seedlings.do... by Mostafa M. Rady (14004633)

“…<p>Abiotic stress significantly damages crops, reducing global yields by over 50%. Among these challenges, salt stress poses a critical constraint that severely affects the growth, productivity, and quality of soybeans in various regions worldwide. …”

Changes in human intervertebral disc biochemical composition and bony end plates between middle and old age by Delio Eulalio Martins (5759282)

“…</p><p>Results</p><p>The old-aged group showed a decrease in content of sulphated and non-sulphated glycosaminoglycans relative to middle-aged and there were also alterations in the proportion of GAG disaccharides and a decrease of collagen fiber size. …”

Donor and Geometry Optimization: Fresh Perspectives for the Design of Polyoxometalate Charge Transfer Chromophores by Bethany R. Hood (20396768)

<i>In-situ</i> recording of ionic currents in projection neurons and Kenyon cells in the olfactory pathway of the honeybee - Fig 2 by Jan Kropf (178122)

“…The PN started to generate APs at ~ -50mV, the KC at -40 mV. B: Representative voltage clamp recordings of an l-ALT PN and a KC. …”