Gal-3 upregulation in hypoxia depends on HIF-1α and NF-κB and is blocked by cicloheximide. by Rafael Yamashita Ikemori (698128)

The miR-181c inhibitor suppresses hESC differentiation. by Zhenyu Xu (105102)

BRET² measurement of Gα_qβ₁γ₂ complex activation in HEK293 living cells expressing equal amounts of the WT of human TP receptor or its E1... by Valérie Capra (396007)

Global changes of DNA methylation during early human development. by Hiroaki Okae (673321)

“…<b>B,</b> Detection of dynamic methylation changes using a sliding window (window size  = 20 CpGs, step size  = 10 CpGs). …”

Synaptotoxic PrP^Sc species are propagated from early in the evolution of M1000 prion disease. by Simote Totauhelotu Foliaki (5614364)

“…The HFS trains were applied following 30 minutes of baseline recordings. (A, C, D) Results are presented as mean ± standard error of mean. …”

Antibodies of the PGT121 family compete with sCD4, but not PGV04, for binding to gp120 in solution and on the cell-surface. by Jean-Philippe Julien (135641)

GBE treatment improved mitochondrial capacity. by Virginie Rhein (243241)

Video_1_Virtual Footprints Can Improve Walking Performance in People With Parkinson's Disease.MP4 by Luis I. Gómez-Jordana (5640137)

“…In all conditions the PD group showed reduced levels of gait variability (p < 0.05) while the HC group did not decrease. For step velocity there was a significant increase in the temporal conditions, the spatial conditions and of the interaction between the two for both groups of participants (p < 0.05). …”

Flow diagram for generation of ZFN mutants, and HRMA analysis. by Lingyan Xing (310457)

“…<p>(A) Flow diagram illustrating steps in generation and identification of fish carrying ZFN-induced mutation. …”

The effect on gliding responses of adding wings to looming discs with varying <i>l/|v|</i>. by Roger D. Santer (117354)

Stimulus and results of Experiment 4 ‘Pre-exposure in binocular rivalry’. by Maartje Cathelijne de Jong (334147)

“…The effect of pre-exposure duration is better viewed with this correction, because the variability between the participants in the overall mean percept duration was rather large. The decrease of the duration of the pre-exposed percept is not influenced by the duration of the pre-exposure, whereas the duration of the alternative percept is longer after long pre-exposure than after short pre-exposure (in line with the result for the rotating globe, see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030595#pone-0030595-g002" target="_blank">fig. 2C</a>).…”

The kava root extract and kavalactones down-regulate expression of AR and AR target genes (<i>PSA</i> and <i>TMPRSS2</i>) via accelerating the degradation of AR protein. by Xuesen Li (48046)

“…The protein expression of AR and PSA in LNCaP and C4-2B cells after indicated treatments at a concentration of their IC_{50 s} for 16 hours was analyzed by Western blot. α-Tubulin was detected as a loading control. …”

Differential Regulation of Duplicate Light-Dependent Protochlorophyllide Oxidoreductases in the Diatom <i>Phaeodactylum tricornutum</i> by Heather M. Hunsperger (798999)

“…Using the diatom <i>Phaeodactylum tricornutum</i> as a test system, differences in POR protein abundance and <i>por</i> gene expression were examined when this organism was grown on an alternating light:dark cycles at different irradiances; exposed to continuous light; and challenged by a significant decrease in light availability.…”

Assessment of cell viability using quantification of lactate dehydrogenase (LDH) released by lesioned retinas treated with GJ blockers and openers. by Vera Paschon (306542)

“…We have tested two different concentrations of the pharmacological agents, i.e. 50 and 100 µM. We observed no changes in LDH release in retinal explants treated with (A) CBX 50 µM, (B) Quin 50 µM, (C) CBX+Quin 50 µM and (D) TMA 50 µM. …”

Figure 4 from FLT3/CD99 Bispecific Antibody–Based Nanoparticles for Acute Myeloid Leukemia by Atham Ali (19345980)

“…<b>A–D,</b> Trypan blue staining detects a decrease in cell viability across different cell lines FLT3-ITD+/CD99⁺ AML cells (MV4-11, MOLM-13), FLT3−/CD99⁺ cells (U937), and FLT3WT+/CD99⁻ (THP-1). …”

Results of linear models testing variation in different measures of plant response to competition. by Lena Neuenkamp (6941123)

Ex vivo fitness, CTL escape phenotype and sequence evolution of <i>gag</i> p24 CTL escape mutants. by Ryan M. Troyer (265934)

“…The fold escape conferred by each mutation is displayed here as the ratio of effective peptide concentration (EC₅₀) required to elicit 50% of maximal ELISpot signal relative to the pre-escape peptide <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1000365#ppat.1000365-Cao2" target="_blank">[54]</a>. …”

Effectiveness of milking management practices for SCC and TBC levels in milk by Marina Oliveira Daneluz (5670299)

“…For such, the quantile regression method was used to estimate models for the 10th, 50th, and 90th quantiles. The results confirmed that SCC and TBC levels decrease as the number of practices increases. …”

Disease progression phenotypes, clinical cohorts, and our computational framework together with the reproducibility of disease progression pattern. by Kimiyo N. Yamamoto (213724)

TBC1D24 maintains dendritic spines through suppression of ARF6. by Lianfeng Lin (8384634)

“…SecinH3 reversed the TBC1D24-shRNA-induced reduction of dendritic spine density (40–50 dendrites from two independent experiments were quantified for each condition; mean+SEM; **p<0.01, ***p<0.001, ****p<0.0001; one-way ANOVA followed by Tukey analysis). …”