Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... by Alhujaily, Muhanad

“…Background: Tumor glycolysis is a target for cancer chemotherapy. Methylglyoxal (MG) is a reactive metabolite formed mainly as a by-product in anaerobic glycolysis, metabolized by glyoxalase 1 (Glo1) of the glyoxalase system. …”
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High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis by Nabil, Shallik

“…HFNO was associated with a significant decrease in mortality and intubation rates (0.28 (95% CI; 0.19, 0.39) and 0.28 (95% CI; 0.18, 0.41), respectively). …”
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High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis by Nabil, Shallik

“…HFNO was associated with a significant decrease in mortality and intubation rates (0.28 (95% CI; 0.19, 0.39) and 0.28 (95% CI; 0.18, 0.41), respectively). …”
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Performance assessment of renewable energy-fed three-phase grid-connected voltage source converters and boost inverters during DC side faults by Elserougi, A.

“…The simulation results elucidate a significant decrease in the DC fault current in case of boost inverter due to its blocking capability.…”
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Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 by Natalia V, Bhattacharjee

“…CCF50 as a proportion of each 5-year ASFR was predicted using a linear mixed-effects model with fixed-effects covariates (female educational attainment and contraceptive met need) and random intercepts for geographical regions. …”
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Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 by Natalia V, Bhattacharjee

“…CCF50 as a proportion of each 5-year ASFR was predicted using a linear mixed-effects model with fixed-effects covariates (female educational attainment and contraceptive met need) and random intercepts for geographical regions. …”
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Impact of fines type on gas flow using 3D micro-computed tomography by Al-Raoush, Riyadh

“…Therefore, there is a need to model and quantify fines impact on multi-phase flow using 3D reconstruction to better understand gas recovery systems. …”
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Analysis of bioconvection and oxytactic microorganisms in a porous cavity with nano-enhanced phase change materials and quadrant heater: Application of support vector regression ba... by Hussain, Shafqat

“…The Galerkin finite element method (GFEM) is employed to compute the governing equations for the considered system by developing a computer code. The study is performed for wide range of parameters as aspect ratio, Darcy number, Hartmann number, nanoparticle fraction, bioconvection Rayleigh number and natural convection Rayleigh number were tested. …”
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A Methodology for daylight optimisation of high-rise buildings in the dense urban district using overhang length and glazing type variables with surrogate modelling by Ekici B.

“…Integrating daylight performance in building design supports reducing the energy consumption and satisfying occupants' comfort. This study presents a methodology to optimise the daylight performance of a high-rise building located in a dense urban district. …”
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Anticoagulant activity of cellulose nanocrystals from isora plant fibers assembled on cellulose and sio2 substrates via a layer-by-layer approach by Mohan T.

“…In this study, we report the isolation of cellulose nanocrystals (CNCs) from Isora plant fibers by sulfuric acid hydrolysis and their assembly on hydrophilic cellulose and silicon-di-oxide (SiO2) surfaces via a layer-by-layer (LBL) deposition method. The isolated CNCs were monodis-persed and exhibited a length of 200-300 nm and a diameter of 10-20 nm, a negative zetapotential (34-39 mV) over a wide pH range, and high stability in water at various concentrations. …”
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Growth performance, intestinal histomorphology, gut microflora and ghrelin gene expression analysis of broiler by supplementing natural growth promoters: A nutrigenomics approach by Gilani, S.M.H.

“…In an epoch of escalating number of antibiotic-resistance bacteria, there is a dire need to develop efficient and novel feeding strategies for animal nutrition as alternatives to antibiotics. …”
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The role of type II FB (I):Tl+ defect in laser light generation and color image formation at the low coordination surface sites of AgBr: Ab initio calculations by Shalabi, A.S.

“…The calculated Stokes shifted optical transition bands suggest that laser activity is relatively weak and fades quickly as the coordination number of the surface ions decreases from 5 (flat) to 4 (edge) to 3 (corner). …”
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A Reduction in Maximal Incremental Exercise Test Duration 48 h Post Downhill Run Is Associated with Muscle Damage Derived Exercise Induced Pain. by Chrismas, Bryna C R

“…Conclusion: EIMD resulted in premature termination of a MIE test (decreased TTE), which was associated with EIP, MVC, and VA. …”
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Rhus coriaria induces senescence and autophagic cell death in breast cancer cells through a mechanism involving p38 and ERK1/2 activation by El Hasasna, Hussain

“…No proliferative recovery was detected after RCE removal. Annexin V staining and PARP cleavage analysis revealed a minimal induction of apoptosis in MDA-MB-231 cells. …”
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Cutaneous Aβ-Non-nociceptive, but Not C-Nociceptive, Dorsal Root Ganglion Neurons Exhibit Spontaneous Activity in the Streptozotocin Rat Model of Painful Diabetic Neuropathy . by Djouhri, Laiche

“…Compared with control, we found in STZ-rats with established pain hypersensitivity (5 weeks post-STZ) several significant changes including: (a) A 23% increase in the incidence of spontaneous activity (SA) in Aβ-LTMs (but not C-mechanosensitive nociceptors) that may cause dysesthesias/paresthesia suffered by DPNP patients, (b) membrane hyperpolarization and a ∼85% reduction in SA rate in Aβ-LTMs by K7 channel activation with retigabine (6 mg/kg, i.v.) suggesting that K7/M channels may be involved in mechanisms of SA generation in Aβ-LTMs, (c) decreases in AP duration and in duration and amplitude of afterhyperpolarization (AHP) in C-and/or Aβ-nociceptors. …”
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Antagonistic Effects of Trichoderma harzianum Isolates against Ceratocystis radicicola: pioneering a Biocontrol Strategy against Black Scorch Disease in Date Palm Trees by Al-Naemi, Fatima A.

“…The aim of this study was to develop a method of biological control through the isolation, identification and examination of the effectiveness of bioagents in controlling black scorch disease. …”
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Artificial weathering and accelerated heat aging studies on low-density polyethylene (Ldpe) produced via autoclave and tubular process technologies by Luyt, A. S.

“…In particular, a mechanism of chain scission/branch-ing that resulted in crosslinking was assumed for the neat polyethylenes, after combining the decrease of molecular weight observed in the GPC analysis with the increase in Young's modulus after UV exposure. …”
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VANET-based smart navigation for emergency evacuation and special events by Elbery A.

“…The objective of the proposed system is to clear the network in a shorter time by better utilizing the network resources while taking into consideration the road capacities. …”
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A precious-metal-free Fe-intercalated carbon nitride porous-network with enhanced activity for the oxygen reduction reaction and methanol-tolerant oxygen reduction reaction by Bin Yousaf, Ammar

“…The C and N-rich additives help generate abundant Fe-Nxand N-C active sites for enhanced oxygen reduction reaction (ORR) under acidic and alkaline conditions and show a negligible decrease in activity after 2000 scan cycles. …”
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Influence of fuel ratio on the performance of combustion synthesized bifunctional cobalt oxide catalysts for fuel cell application by Ashok A.

“…The kinetic current density for Co (φ = 0.5) is 6.45 mA cm−2 and decreases with increase in fuel ratio. …”
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