Metabolic Erosion Primarily Through Mutation Accumulation, and Not Tradeoffs, Drives Limited Evolution of Substrate Specificity in <i>Escherichia coli</i> by Nicholas Leiby (424634)

“…We assayed the ability of the Lenski <i>Escherichia coli</i> populations to grow on a range of carbon sources after 50,000 generations of adaptation on glucose. …”

Leaf extracts of Campomanesia xanthocarpa positively regulates atherosclerotic-related protein expression by EDUARDO B.B. CUNHA (10363794)

“…Cell viability was affected only at higher concentrations and times. We observed decreased ICAM-1 expression in cells treated with 50 μg/ml EG and CD14 expression with IFN-γ and without IFN-γ. …”

Rapid chemical de-N-glycosylation and derivatization for liquid chromatography of immunoglobulin N-linked glycans by Akihiko Kameyama (2033902)

“…For N-linked glycan analysis, we investigated alkaline hydrolysis of the asparagine glycosyl carboxamide of glycoproteins as a deglycosylation reaction. …”

Table1_Frequencies of Porphyromonas gingivalis Detection in Oral-Digestive Tract Tumors.DOC by Jinyu Kong (489468)

“…In conclusion, the detection rate of P. gingivalis showed a decreasing trend in oral-digestive tract tumors. …”

S1 Data - by Karl Magtibay (10851678)

“…We measured their effects on spatial and temporal heterogeneity of action potential durations (APD) at 50% and 20%. …”

Effects of HAI-1 and HAI-2 overexpression and downregulation on cell proliferation in NPCs. by Raili Koivuniemi (280720)

“…(<b>C</b>) Immunoblot of the cell cycle regulator, CyclinD1. ß-actin was used as a control. Quantification below shows a decrease in CyclinD1 after HAI-1 and HAI-2 expression. …”

CM inhibits adhesion of U937s and adhesion molecule expression in PECs. by Shibani Pati (208746)

“…After gentle washing, bound cells were quantitatively and qualitatively assessed. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0025171#pone-0025171-g002" target="_blank">Figure 2A</a> shows decreased binding of U937 (green dots) in CM treated cultures. …”

Sequence conservation in hemagglutinin groups and subtypes. by Nicola Clementi (174058)

“…<p>Boxes indicate mutated residues which decrease PN-SIA28 binding to mutated HAs. Circles on the top indicate PN-SIA28 percent binding to each HA alanine mutants compared to binding to wild-type HA: red 25% binding, yellow 50–75% binding. …”

Factors that drive zooplankton diversity in Neo-Tropical Savannah shallow lakes by Claudia Padovesi-Fonseca (4653880)

DataSheet_1_Unraveling IFN-I response dynamics and TNF crosstalk in the pathophysiology of systemic lupus erythematosus.docx by Laura C. Van Eyndhoven (10723122)

Simulations with mutating cells and stable vasculature. by András Szabó (3034779)

“…During the cell number drop the pressure is moderated to almost half, after which it is increasing to reach a plateau. The tissue coverage drops from the initial full coverage to approximately 50%. …”

No major role for rare plectin variants in arrhythmogenic right ventricular cardiomyopathy by Edgar T. Hoorntje (5703347)

Cholesterol-Independent Effects of Methyl-β-Cyclodextrin on Chemical Synapses by Kiel G. Ormerod (166248)

“…The reduction in EJP amplitude in the cold-acclimatized group was associated with a 49% reduction in quantal content (P<0.05). MβCD had no effect on input resistance in muscle fibers but decreased sensitivity to the neurotransmitter L-glutamate in both warm- and cold-acclimatized groups. …”

<b>Single-dose replicon RNA Sudan virus vaccine uniformly protects female guinea pigs from disease</b> by Andrea Marzi (758337)

“…There are currently no licensed countermeasures against SUDV. We developed a SUDV vaccine candidate based on a nanocarrier (LION^TM) complexed with an alphavirus-based replicon RNA. …”

Manifold transformation in the familiarity association experiment. by Weifan Wang (4669081)

“…<b>(E)</b> Across noise levels, and over the first 200 epochs show a two-phase trajectory: a minimum at epoch 30 (dashed line), and an overall decrease. …”

Network Signatures of Survival in Glioblastoma Multiforme by Vishal N. Patel (242677)

“…<div><p>To determine a molecular basis for prognostic differences in glioblastoma multiforme (GBM), we employed a combinatorial network analysis framework to exhaustively search for molecular patterns in protein-protein interaction (PPI) networks. …”

Characterization of α-syn pores. by Felix Schmidt (312801)

“…<p><b>A</b>) Depending on clamped voltage, the number of steps increasing or decreasing pore conductance (“G-up” and “G-down” refer to the number of steps per recorded trace of 10s) differs (N = 18804 steps in 74 pore formations with 42 traces each). …”

Incident light intensities and cellular parameters. by Benjamin Schellenberger Costa (461158)

“…<p><i>Aureo1a-15</i> and <i>aureo1a-50</i><i>P. tricornutum</i> cultures were grown under illumination with blue (BL) and red light (RL) under limiting light (LL, Q_Phar = 10 µmol absorbed photons m⁻² s⁻¹) and medium light (ML, Q_Phar = 30 µmol absorbed photons m⁻² s⁻¹) conditions; corresponding WT data of Schellenberger Costa et al. …”

Optimization of TEV protease cleavage conditions. by Yu-Fu Hung (513472)

“…The different “+” font sizes indicate the increasing amounts of TEV protease with fusion peptide to protease molar ratios of approximately 100, 50 and 10. The progress of the TEV digest is monitored by observing the decrease of the band of the dual tagged GST-GB1-NS4A(1–48) fusion protein and a parallel increase of the free GST-GB1 dual tag band (B, D).…”

Table_1_Associations Between Dietary Inflammatory Index and Sex Hormones Among 6- to 19-Year-Old Children and Adolescents in NHANES 2015–2016.docx by Yuxia Ma (5087672)

“…The constructed puberty state is defined as high levels of steroid hormones (TT≥50 ng/dL in men, E2≥20 pg/ml in women) or onset of menarche. …”