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1141
Ubiquitin-Related Modifier 1 (URM-1) Modulates Cx43 in Breast Cancer Cell Lines.
Published 2023“…In particular, the PTM of connexin 43 (Cx43), a tumor suppressor protein, regulates its turnover and activity. …”
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1142
Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents
Published 2023“…Targeting inflammation in cancer associated with chronic inflammation is a promising therapy. In the present study, we investigated the anti-inflammatory effects of fluorinated benzofuran and dihydrobenzofuran derivatives in macrophages and in the air pouch model of inflammation, as well as their anticancer effects in the human colorectal adenocarcinoma cell line HCT116. …”
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1143
Gas Driven Fracture during Gas Production using HeleShaw Cell
Published 2018“…Methane hydrate is considered a potential energy source, with worldwide reserves on the order of 500-10,000 Gt of carbon. …”
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1144
Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice
Published 2024“…These findings were found to be correlated with increased level of oxidative stress, neuroinflammation, and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (BDNF), which plays an essential role in modulating synaptic plasticity integral for promoting learning and memory in the hippocampus. Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”
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1145
Tandem osmotic engine based on hydrogel particles with antipolyelectrolyte and polyelectrolyte effect fuelled by both salinity gradient modes
Published 2021“…In this study, we propose a new approach to attain energy by salinity gradient engines with pistons based on hydrogels possessing polyelectrolyte and antipolyelectrolyte effects in a tandem arrangement, providing energy in each salinity gradient mode in a repeatable manner. …”
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1146
Conceptual Based Hidden Data Analytics and Reduction Method for System Interface Enhancement Through Handheld devices
Published 2016“…In addition, by using online consecutive reductions on search results, we adopted a method of displaying results in order of decreasing relevance. …”
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1147
Screening the growth inhibition mechanism of sulfate reducing bacteria by chitosan/lignosulfonate nanocomposite (CS@LS) in seawater media
Published 2021“…Herein, we have developed a biodegradable chitosan/lignosulfonate nanocomposite (CS@LS) as an efficient green biocide for the inhibition of SRBs biofilms. …”
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1148
Synthesis and properties of HA/ZnO/CNT nanocomposite
Published 2018“…The goal of this study was to examine the tribomechanical properties of hydroxyapatite (HA)/ZnO and HA/ZnO/CNT composite ceramics (carbon nanotubes; with different ratios 0.5 wt%, 1.0 wt%, and 1.5 wt%). The composites were synthesized using the hydrothermal method in an autoclave. …”
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1149
VacoNet: Variable and connected architecture for data center networks
Published 2016“…Motivated by these challenges, we propose a new data center architecture called VacoNet that combines the advantages of existing architectures while avoiding their limitations. …”
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1150
Dynamic workload patterns prediction for proactive auto-scaling of web applications
Published 2018“…This may lead to inappropriate resource provisioning decisions. In this paper, we address these challenges by proposing a framework for prediction of dynamic workload patterns as follows. …”
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1151
Biochemical and structural impact of two novel missense mutations in cystathionine β-synthase gene associated with homocystinuria
Published 2024“…In this study, we present the clinical and biochemical characterization of two novel CBS missense mutations that do not respond to pyridoxine treatment, namely c.689T > A (L230Q) and 215A > T (K72I), identified in a Chinese patient. …”
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1152
Synthesis and characterization of stir casted Cu-ZrO2-Graphite hybrid metal matrix composites for thermal management structures
Published 2022“…ZrO2 and Graphite reinforcements were added (0.5–0.5, 1.0–1.0, 1.5–1.5 and 2.0–2.0 wt %) in the four composite samples prepared via stir casting. …”
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1153
Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs
Published 2022“…Moreover, miRNA, piRNA, and snoRNAs expression profiles in iPSCs and original fibroblasts were assessed to identify the potential role of ncRNAs in enhancing iPSC generation, pluripotency, and differentiation. Decreased levels of let-7a-5p showed an increase of SP8 as described previously. …”
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1154
Hydrogel Sensors for the Agricultural Applications
Published 2020“…We chose to use hydrogel in soil, for their high efficiency in absorbing water. …”
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1155
Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight
Published 2021“…From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. …”
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1156
Thermally assisted efficient electrochemical lithium extraction from simulated seawater
Published 2022“…Based on these understandings, we demonstrated that a thermally assisted electrochemical lithium extraction process could achieve rapid (36.8 mg g-1 day-1) and selective (51.79% purity) lithium extraction from simulated seawater with an ultrahigh Na+/Li+ molar ratio of 20,000. …”
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1157
Effect of biochars produced from solid organic municipal waste on soil quality parameters
Published 2017“…Select municipal organic wastes (newspaper, cardboard, woodchips and landscaping residues) individually or in a 25% blend of all four waste streams were used as feedstocks of biochars. …”
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1158
Salinity inhibits seed germination of perennial halophytes Limonium stocksii and Suaeda fruticosa by reducing water uptake and ascorbate dependent antioxidant system
Published 2014“…Germination and hydration of the seeds of both species decreased with increases in NaCl concentration. CAT and GPX activities were higher while APX, AsA and GSH decreased in salt stressed seeds compared to water-imbibed seeds. …”
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1159
Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice
Published 2024“…These findings were found to be correlated with increased level of oxidative stress, neuroinflammation, and apoptosis markers, and reduced expression of brain-derived neurotrophic factor (BDNF), which plays an essential role in modulating synaptic plasticity integral for promoting learning and memory in the hippocampus. Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”
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1160
Quantification of the growth suppression of HER2+ breast cancer colonies under the effect of trastuzumab and PD-1/PD-L1 inhibitor.
Published 2022“…Precisely, several questions regarding the right combination of drugs, drug modality, and effective dose recommendations pertaining to the use of ICB-based therapy for HER2+ patients remain unanswered. In this study, we use a mathematical modeling-based approach to quantify the growth inhibition of HER2+ breast cancer (BC) cell colonies (ZR75) when treated with anti-HER2; trastuzumab (TZ) and anti-PD-1/PD-L1 (BMS-202) agents. …”
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