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1221
In silico and in vivo models for Qatari-Specific classical homocystinuria as basis for development of novel therapies.
Published 2018“…Wildtype CBS, but not the p.R336C mutant, was able to restore the yeast growth in ΔCBS deficient yeast in a complementation assay. The p.R336C knock-in HEK293T and HepG2 cells decreased the level of CBS expression and reduce its structural stability; however, treatment of the p.R336C knock-in HEK293T cells with betaine, a chemical chaperone, restored the stability and tetrameric conformation of CBS, but not its activity. …”
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1222
Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO₂ Photocatalytic Nanocomposites Using the Zebrafish Embryo Model.
Published 2019“…Using the zebrafish embryo model, we investigated the environmental impacts of two thermally (RGOTi)- and hydrogen (H₂RGOTi)-reduced graphene oxide/TiO₂ semiconductor photocatalysts recently employed in AOPs. …”
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1223
Dietary Intake Is Not Associated with Body Composition nor with Biochemical Tests but with Psychological Status of Cancer Patients Receiving Chemotherapy
Published 2023“…Each participant completed a reliable validated questionnaire, psychological questionnaire, quality of life questionnaire, and three-day food records. …”
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1224
Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via nrf2 pathway in mice with high fat diet-induced obesity
Published 2017“…Abstract Epigallocatechin 3-gallate (EGCG) from green tea may reduce plasma glucose and alleviate complications of diabetes by attenuating advanced glycation end products (AGEs) formation. We hypothesized that EGCG would mitigate AGEs formation via activating the nuclear factor erythroid-2-related-factor-2 (Nrf2) pathway in a mouse model of high fat diet-induced obesity. …”
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1225
Cyclic voltammetry and XPS studies of poly (aniline-co-3-aminophenol)
Published 2022“…In the present work, we prepared enormously soluble poly (aniline-co-3-aminophenol) (PA-co-3-AP) copolymers via a simple chemical oxidative method with aniline and 3-aminophenol, and their properties are compared with conventional polyaniline (PA). …”
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1226
Metabolic consequences of obesity on the hypercoagulable state of polycystic ovary syndrome.
Published 2021“…We determined plasma coagulation pathway protein levels in PCOS (n = 146) and control (n = 97) women recruited to a PCOS biobank. …”
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1227
Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling
Published 2020“…To mimic hypertension, the rat portal vein (RPV) was mechanically stretched, and the protective effects of APN on mechanical stretch-induced vascular remodeling and the molecular mechanisms involved were examined by using 10μg/ml APN. Mechanically stretching the RPV significantly decreased APN protein expression after 24 hours and APN mRNA expression in a time-dependent manner in VSMCs. …”
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1228
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1229
Tailoring the defects of sub-100 nm multipodal titanium nitride/oxynitride nanotubes for efficient water splitting performance
Published 2021“…Deciphering the photocatalytic-defect relationship of photoanodes can pave the way towards the rational design for high-performance solar energy conversion. Herein, we rationally designed uniform and aligned ultrathin sub-100 nm multipodal titanium nitride/oxynitride nanotubes (TiONxNTs) (x = 2, 4, and 6 h) via the anodic oxidation of Ti-foil in a formamide-based electrolyte followed by annealing under ammonia gas for different durations. …”
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1230
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1231
Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up.
Published 2018“…At follow-up in 2007, sleep disorder symptoms, including daytime falling asleep, sleepiness and snoring at night, were gathered using a sleep questionnaire. (3) Results: The mean intake of magnesium was 332.5 mg/day. …”
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1232
Reduced vasorin enhances angiotensin II signaling within the aging arterial wall
Published 2018“…Angiotensin II (Ang II) amplifies TGF-β1 activation in the VSMCs of the arterial wall with aging. In this study, we hypothesized that a reduced expression of the protein vasorin plays a contributory role in magnifying Ang II-associated fibrogenic signaling in the VSMCs of the arterial wall with aging. …”
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1233
Synthesis of silica supported ni and cu catalyst for carbon dioxide methanation reaction
Published 2019“…In this study we investigate the synthesis of nickel and copper catalyst supported on silica for CO2 conversion to methane. …”
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1234
Novel, selective EPO receptor ligands lacking erythropoietic activity reduce infarct size in acute myocardial infarction in rats
Published 2016“…In study 4, AF43136 at 10 mg/kg decreased infarct size, similarly to the positive control CsA compared to the appropriate vehicle (39.4 ± 5.9% vs. 58.1 ± 5.4% and 45.9 ± 2.4% vs. 63.8 ± 4.1%, p < 0.05, respectively). …”
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1235
Western and ketogenic diets in neurological disorders: can you tell the difference?
Published 2022“…Here, we discuss the principles of brain metabolism with a focus on the distinct effects of the Western and ketogenic diets on the progression of neurological diseases such as epilepsy, Parkinson's disease, Alzheimer's disease, and traumatic brain injury, highlighting the need to further explore the potential therapeutic effects of the ketogenic diet and the importance of standardizing dietary formulations to assure the reproducibility of clinical trials.…”
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1236
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1237
New genetic insights into improving barley cope with salt stress via regulating mineral accumulation, cellular ion homeostasis, and membrane trafficking
Published 2023“…This study was designed to explore the natural variation of responsive physiological and agronomic traits in a diverse spring barley panel under salt-affected soil and the application of selenium nanoparticles (Se-NP) during the vegetative phase. …”
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1238
Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose
Published 2021“…Endothelial-to-mesenchymal-transition (EndMT) appears to play a role in diabetes-associated fibrotic conditions. …”
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1239
Correlations between Resting Electrocardiogram Findings and Disease Profiles: Insights from the Qatar Biobank Cohort
Published 2024“…Background: Resting electrocardiogram (ECG) is a valuable non-invasive diagnostic tool used in clinical medicine to assess the electrical activity of the heart while the patient is resting. …”
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1240
Impacts of rural tourism-driven land use change on ecosystems services provision in Erhai Lake Basin, China
Published 2020“…With these land changes, ecosystem services also changed greatly, to the detriment of ELB as a whole and especially the lakeside zone. By 2015, soil retention had decreased and nitrogen and soil export had increased, compared with the levels in 2000, while there was only a slight fluctuation in carbon storage and water yield. …”
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