Identification of an amino-terminus determinant critical for ryanodine receptor/Ca2+ release channel function. حسب Seidel, Monika

"…The negatively-charged side chains of two aspartate residues (D179 and D180) within the β8-β9 loop are crucial for the N-terminal inter-subunit interaction. We also show that the RyR2 N-terminus domain interacts with the C-terminal channel pore region in a Ca2+-independent manner. …"
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Paradoxical Effect of Nonalcoholic Red Wine Polyphenol Extract, Provinols™, in the Regulation of Cyclooxygenases in Vessels from Zucker Fatty Rats (fa/fa) حسب Agouni, Abdelali

"…We provide here evidence of a subtle and paradoxical regulation of COX pathway by Provinols vessels from obese rats to maintain vascular tone within a physiological range.…"
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Potassium transport and use efficiency for sustainable fertigation in protected cropping حسب Sonali

"…We review different K+ channels and transporters from various protein families responsible for K+ absorption and distribution across different plant tissues. …"
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Silymarin-albumin nanoplex: Preparation and its potential application as an antioxidant in nervous system in vitro and in vivo حسب Sohrabi M.J.

"…In this study, we formulated silymarin-HSA nanoplex and assayed its ability to reduce LPS-induced toxicity in vitro and in vivo. …"
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Co-doped zigzag graphene nanoribbon based gas sensor for sensitive detection of H2S: DFT study حسب Salih, Ehab

"…In this work, we present a highly sensitive gas sensor for the detection of poisonous hydrogen sulfide gas (H2S) based on copper and zinc co-doped zigzag graphene nanoribbon (Cu/Zn-ZGNR). …"
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Preterm birth in low-middle income Countries حسب Alim, Swarray-Deen

"…Preterm birth (PTB), remains a major cause of significant morbidity and mortality world-wide with about 12–15million preterm births occurring every year. …"
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Emerging clay-aryl-gold nanohybrids for efficient electrocatalytic proton reduction حسب Jlassi, Khouloud

"…One of the alternatives is usage of hydrogen production by electrochemical hydrogen evolution reaction (HER). Toward this end, we have successfully prepared a novel, robust electrocatalyst for HER containing Au nanoparticles dispersed on a natural bentonite using a simple one-pot reduction process. …"
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CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS حسب ELJILANY, ISLAM AHMED SAYED AHMED

"…To optimize the period of preprocedural warfarin interruption to decrease the incidence of bleeding in case of bridging and the incidence of thromboembolism in case of non-bridging, a study was conducted to determine the influence of CYP2C9, VKORC1, CYP4F2, FII, and FVII genetic polymorphisms and non-genetic factors on INR decline in a cohort of Arabs undergoing a procedure that requires warfarin interruption and developing an algorithm to tailor the duration of warfarin interruption before the procedure. …"
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Salvia fruticosa Induces Vasorelaxation in Rat Isolated Thoracic Aorta: Role of the PI3K/Akt/eNOS/NO/cGMP Signaling Pathway حسب Anwar, M. Akhtar

"…Pretreatment of endothelium-intact rings with L-NAME (a non-selective inhibitor of nitric oxide synthase, 100 µM), or ODQ (an inhibitor of soluble guanylyl cyclase, 10 µM) significantly diminished SF-mediated vasorelaxation. …"
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Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf) حسب Connor, Izumi

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Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf) حسب Connor, Izumi

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Edge Intelligence for Empowering IoT-Based Healthcare Systems حسب Hayyolalam, Vahideh

"…To meet the increasing demands on this critical infrastructure, there is a need for intelligent methods to cope with the existing related challenges. …"
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Sulforaphane reduces obesity by reversing leptin resistance. حسب Çakır, Işın

"…Here, we show that the natural isothiocyanate and potent NRF2 activator sulforaphane reverses diet-induced obesity through a predominantly, but not exclusively, NRF2-dependent mechanism that requires a functional leptin receptor signaling and hyperleptinemia. …"
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Fractionation and phytochemical composition of an ethanolic extract of Ziziphus nummularia leaves: antioxidant and anticancerous properties in human triple negative breast cancer c... حسب Abdallah, Rola

"…Natural products have long been utilized in traditional medicine as remedies to improve health and treat illnesses, and have had a key role in modern drug discovery. Recently, there has been a revived interest in the search for bioactives from natural sources as alternative or complementary modalities to synthetic medicines; especially for cancer treatment, which incidence and mortality rates are on the rise worldwide. …"
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Nickel Toxicity Interferes with NO3−/NH4+ Uptake and Nitrogen Metabolic Enzyme Activity in Rice (Oryza sativa L.) حسب Rizwan, Muhammad

"…A Ni concentration of 200 µM significantly decreased the NO3− concentration in rice leaves, as well as the activities of nitrate reductase (NR), nitrite reductase (NiR), glutamine synthetase (GS), and glutamate synthetase (GOGAT), respectively, when compared to the control. …"
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In silico and in vivo models for Qatari-Specific classical homocystinuria as basis for development of novel therapies. حسب Ismail, Hesham M

"…Wildtype CBS, but not the p.R336C mutant, was able to restore the yeast growth in ΔCBS deficient yeast in a complementation assay. The p.R336C knock-in HEK293T and HepG2 cells decreased the level of CBS expression and reduce its structural stability; however, treatment of the p.R336C knock-in HEK293T cells with betaine, a chemical chaperone, restored the stability and tetrameric conformation of CBS, but not its activity. …"
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Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO₂ Photocatalytic Nanocomposites Using the Zebrafish Embryo Model. حسب Al-Kandari, Halema

"…Using the zebrafish embryo model, we investigated the environmental impacts of two thermally (RGOTi)- and hydrogen (H₂RGOTi)-reduced graphene oxide/TiO₂ semiconductor photocatalysts recently employed in AOPs. …"
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Dietary Intake Is Not Associated with Body Composition nor with Biochemical Tests but with Psychological Status of Cancer Patients Receiving Chemotherapy حسب Subih, Hadil S.

"…Each participant completed a reliable validated questionnaire, psychological questionnaire, quality of life questionnaire, and three-day food records. …"
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Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via nrf2 pathway in mice with high fat diet-induced obesity حسب Sampath, Chethan

"…Abstract Epigallocatechin 3-gallate (EGCG) from green tea may reduce plasma glucose and alleviate complications of diabetes by attenuating advanced glycation end products (AGEs) formation. We hypothesized that EGCG would mitigate AGEs formation via activating the nuclear factor erythroid-2-related-factor-2 (Nrf2) pathway in a mouse model of high fat diet-induced obesity. …"
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Cyclic voltammetry and XPS studies of poly (aniline-co-3-aminophenol) حسب Waware, Umesh Somaji

"…In the present work, we prepared enormously soluble poly (aniline-co-3-aminophenol) (PA-co-3-AP) copolymers via a simple chemical oxidative method with aniline and 3-aminophenol, and their properties are compared with conventional polyaniline (PA). …"
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