Image_3_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.TIF by Emilie Lesport (19214344)

“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”

Table_1_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.DOCX by Emilie Lesport (19214344)

“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”

Image_2_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.TIF by Emilie Lesport (19214344)

“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”

Video_2_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.AVI by Emilie Lesport (19214344)

“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”

Video_3_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.AVI by Emilie Lesport (19214344)

“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”

Image_1_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.TIF by Emilie Lesport (19214344)

“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”

Video_1_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.AVI by Emilie Lesport (19214344)

“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”

Table_2_A decrease in Fkbp52 alters autophagosome maturation and A152T-tau clearance in vivo.docx by Emilie Lesport (19214344)

“…<p>The failure of the autophagy-lysosomal pathway to clear the pathogenic forms of Tau exacerbates the pathogenesis of tauopathies. We have previously shown that the immunophilin FKBP52 interacts both physically and functionally with Tau, and that a decrease in FKBP52 protein levels is associated with Tau deposition in affected human brains. …”

Nanomolar Caffeic Acid Decreases Glucose Uptake and the Effects of High Glucose in Endothelial Cells by Lucia Natarelli (823310)

“…In HG, the presence of 10 nM caffeic acid was associated with a decrease of glucose uptake but not to changes of GLUT-1 membrane localization or mRNA levels. …”

Beneficial effects of a gait used while wearing a kimono to decrease the knee adduction moment in healthy adults by Susumu Ota (4167205)

“…Most of the modifications, however, involve voluntary changes in leg alignment. Here we investigated the biomechanical effects for reducing the KAM of a walking style with a small trunk rotation and arm swing gait, which is a natural walking style used while wearing a kimono (Nanba walk) that shifts the ground reaction force toward the stance leg (reduced lever arm). …”

A possible explanation for a nonlinear decline in populations could be a decrease in active AMP concentration over time due to degradation. by Alexandro Rodríguez-Rojas (326213)

Targeting Hormone-Related Pathways to Improve Grain Yield in Rice: A Chemical Approach by Hiroaki Tamaki (758505)

“…NDGA inhibited the expression of ABA-responsive gene, but did not significantly decrease ABA content. Instead, NDGA significantly decreased jasmonic acid and jasmonic acid-isoleucine. …”

Patient flow diagram. by Lucas L. A. Nunes (19360381)

“…A significant decrease in hepcidin and FGF-23 levels was observed. …”

ACE2 Is Augmented in Dystrophic Skeletal Muscle and Plays a Role in Decreasing Associated Fibrosis by Cecilia Riquelme (546116)

“…<div><p>Duchenne muscular dystrophy (DMD) is the most common inherited neuromuscular disease and is characterized by absence of the cytoskeletal protein dystrophin, muscle wasting, and fibrosis. We previously demonstrated that systemic infusion or oral administration of angiotensin-(1-7) (Ang-(1-7)), a peptide with opposing effects to angiotensin II, normalized skeletal muscle architecture, decreased local fibrosis, and improved muscle function in <i>mdx</i> mice, a dystrophic model for DMD. …”

Table_1_Improvement of Emotional Empathy and Cluster B Personality Disorder Symptoms Associated With Decreased Cocaine Use Severity.docx by Matthias Vonmoos (759842)

“…The categorization of the two cocaine user groups was based on a combination of absolute (± 0.5 ng/mg) and relative (± 10%) changes in the cocaine hair concentration between baseline and the 1-year follow-up. …”

Decreased miR-26a Expression Correlates with the Progression of Podocyte Injury in Autoimmune Glomerulonephritis by Osamu Ichii (339354)

“…<div><p>MicroRNAs contribute to the pathogenesis of certain diseases and may serve as biomarkers. We analyzed glomerular microRNA expression in B6.MRLc1, which serve as a mouse model of autoimmune glomerulonephritis. …”

Targeting <em>A20</em> Decreases Glioma Stem Cell Survival and Tumor Growth by Anita B. Hjelmeland (104655)

“…Inhibiting A20 expression decreased GSC growth and survival through mechanisms associated with decreased cell-cycle progression and decreased phosphorylation of p65/RelA. …”

A Knockout Mutation of a Constitutive GPCR in <em>Tetrahymena</em> Decreases Both G-Protein Activity and Chemoattraction by Thomas J. Lampert (194549)

“…One of these knockout mutants, called G6, is a complete knockout of a gene that we call GPCR6 (TTHERM_00925490). …”

Decreased respiratory performance of children and adolescents with myelomeningocele who use a wheelchair – preliminary data by E.J. Martins (7141313)

“…MMC (n=10) and healthy (n=25) participants of both genders with a mean age of 12.45 years (SD=2.1) were assessed for weight, height, respiratory performance, and isometric peak for shoulder flexors, extensors, abductors, and adductors, using an isokinetic dynamometer. …”

As the protein lifetime decreases, a trade-off between dynamical and mechanistic error determines fidelity. by Clive G. Bowsher (395875)

“…<p>We consider a 2-stage model of gene expression with the input, , equal to the current rate of transcription, and the signal of interest . …”