DataSheet_1_Correlative analysis from a phase I clinical trial of intrapleural administration of oncolytic vaccinia virus (Olvi-vec) in patients with malignant pleural mesothelioma... by Navin K. Chintala (14631764)

“…Vaccinia virus was detectable in tumor cells 2-5 days post-treatment, and treatment was associated with a decrease in tumor cell density and an increase in immune cell density as assessed by a pathologist blinded to the clinical observations. …”

Table1_Effectiveness and safety of tenofovir amibufenamide and its comparison with tenofovir alafenamide in patients with chronic hepatitis B: results from a retrospective real-wor... by Lanqing Li (11505488)

DataSheet_2_Isoliquiritigenin Derivative Regulates miR-374a/BAX Axis to Suppress Triple-Negative Breast Cancer Tumorigenesis and Development.pdf by Fu Peng (1426402)

“…PCR arrays demonstrate a significant decrease in miR-374a expression in TNBC cells after 24-h TMC treatment. …”

DataSheet_1_Isoliquiritigenin Derivative Regulates miR-374a/BAX Axis to Suppress Triple-Negative Breast Cancer Tumorigenesis and Development.zip by Fu Peng (1426402)

“…PCR arrays demonstrate a significant decrease in miR-374a expression in TNBC cells after 24-h TMC treatment. …”

Cullin4 Is Pro-Viral during West Nile Virus Infection of <i>Culex</i> Mosquitoes by Prasad N. Paradkar (237821)

“…We also show that gene knockdown of <i>Culex</i> Cul4 leads to activation of the Jak-STAT pathway in mosquitoes leading to decrease viral replication in the body as well as saliva. …”

Image_2_Cell-Specific Protective Signaling Induced by the Novel AT2R-Agonist NP-6A4 on Human Endothelial and Smooth Muscle Cells.JPEG by Ryan Toedebusch (5651510)

“…To elucidate further the protective effects of NP-6A4 in human cells, we studied the effects of NP-6A4 treatment on functions of human coronary artery endothelial cells (hCAECs), and hCAVSMCs. …”

Image_1_Cell-Specific Protective Signaling Induced by the Novel AT2R-Agonist NP-6A4 on Human Endothelial and Smooth Muscle Cells.JPEG by Ryan Toedebusch (5651510)

“…To elucidate further the protective effects of NP-6A4 in human cells, we studied the effects of NP-6A4 treatment on functions of human coronary artery endothelial cells (hCAECs), and hCAVSMCs. …”

Data_Sheet_1_Agriculture by Irrigation Modifies Microbial Communities and Soil Functions Associated With Enhancing C Uptake of a Steppe Semi-Arid Soil in Northern Patagonia.PDF by Juan P. Frene (12227753)

Data_Sheet_1_Agriculture by Irrigation Modifies Microbial Communities and Soil Functions Associated With Enhancing C Uptake of a Steppe Semi-Arid Soil in Northern Patagonia.PDF by Juan P. Frene (12227753)

Image_1_The Predictive Value of Estrogen Receptor 1 on Adjuvant Chemotherapy in Locally Advanced Colorectal Cancer: A Retrospective Analysis With Independent Validation and Its Pot... by Shu-Biao Ye (4264795)

“…ESR1 expression was significantly correlated with 5-flurouracil (5-FU)-based adjuvant chemotherapy in training with an HR of 1.792 (95%CI: 1.100–2.921, p = 0.019). Downregulation of ESR1 was related with enhanced chemosensitivity to 5-FU in CRC cell lines, while upregulation of ESR1 was correlated with decreased chemosensitivity.…”

Supplementary Material for: Efficacy of Rituximab for Minimal Change Disease and Focal Segmental Glomerulosclerosis with Frequently Relapsing or Steroid-Dependent Nephrotic Syndrom... by Lan L. (17388316)

“…The relapse frequency, calculated as the ratio of relapse times to follow-up years, significantly decreased after rituximab treatment [0.04 (0.00, 0.08) vs. 1.71 (1.00, 2.45), P < 0.001]. …”

Data_Sheet_1_MKI-1, a Novel Small-Molecule Inhibitor of MASTL, Exerts Antitumor and Radiosensitizer Activities Through PP2A Activation in Breast Cancer.doc by Ah-Young Kim (531209)

“…The mechanism of action of MKI-1 occurred through an increase in PP2A activity, which subsequently decreased the c-Myc protein content in breast cancer cells. …”

DataSheet_1_JNK Signaling Pathway Mediates Acetaminophen-Induced Hepatotoxicity Accompanied by Changes of Glutathione S-Transferase A1 Content and Expression.docx by Chenxi Shi (7407551)

“…The results showed that JNK signaling pathway was activated by APAP in a dose-dependent manner. C-Jun N-terminal kinase inhibitor decreased JNK and c-Jun activation significantly (P < 0.01) at 175 mg·kg⁻¹ APAP dose, and phosphorylation levels of upstream proteins of JNK were also decreased markedly (P < 0.05). …”

Top GO categories and KEGG pathways related to DEGs. by Foluwasomi A. Oyefeso (15999113)

Presentation1_Obesity exacerbates influenza-induced respiratory disease via the arachidonic acid-p38 MAPK pathway.PPTX by Ravishankar Chandrasekaran (16868877)

“…Primary human nasal epithelial cells (pHNECs) derived from obese compared with lean individuals developed increased inflammation and injury in response to influenza A virus (IAV). Obese mice infected with influenza developed increased airway inflammation, lung injury and elastance, but had a decreased interferon response, compared with lean mice. …”

Table1_Obesity exacerbates influenza-induced respiratory disease via the arachidonic acid-p38 MAPK pathway.XLSX by Ravishankar Chandrasekaran (16868877)

“…Primary human nasal epithelial cells (pHNECs) derived from obese compared with lean individuals developed increased inflammation and injury in response to influenza A virus (IAV). Obese mice infected with influenza developed increased airway inflammation, lung injury and elastance, but had a decreased interferon response, compared with lean mice. …”

Table_1_Trends in outpatient and inpatient visits for separate ambulatory-care-sensitive conditions during the first year of the COVID-19 pandemic: a province-based study.DOCX by Tetyana Kendzerska (519437)

“…Background<p>The COVID-19 pandemic led to global disruptions in non-urgent health services, affecting health outcomes of individuals with ambulatory-care-sensitive conditions (ACSCs).</p>Methods<p>We conducted a province-based study using Ontario health administrative data (Canada) to determine trends in outpatient visits and hospitalization rates (per 100,000 people) in the general adult population for seven ACSCs during the first pandemic year (March 2020–March 2021) compared to previous years (2016–2019), and how disruption in outpatient visits related to acute care use. …”

Association of Cytotoxic T-Lymphocyte Antigen 4 (<i>CTLA4</i>) and Thyroglobulin (<i>TG</i>) Genetic Variants with Autoimmune Hypothyroidism by Hinal Patel (2559001)

“…Patients had significantly decreased mRNA levels of both s<i>CTLA4</i> (<i>p</i> = 0.0017) and fl<i>CTLA4</i> (<i>p</i><0.0001) compared to controls. +49A/G and CT60 polymorphisms of <i>CTLA4</i> were in moderate linkage disequilibrium. …”

Table1_Network pharmacology and experimental study of phenolic acids in salvia miltiorrhiza bung in preventing ischemic stroke.xlsx by Chengdi Liu (14512106)

“…We further demonstrated that SAA preventive administration reduced neurobehavioral scores, decreased infarct size, and protected tight junction proteins in autologous thrombus stroke model. …”

Table1_Network pharmacology and experimental study of phenolic acids in salvia miltiorrhiza bung in preventing ischemic stroke.xlsx by Chengdi Liu (14512106)

“…We further demonstrated that SAA preventive administration reduced neurobehavioral scores, decreased infarct size, and protected tight junction proteins in autologous thrombus stroke model. …”