Multivariate-adjusted odds ratios for the cause-specific mortality (A: cardiac death, B: cerebrovascular death, C: infection-related death, D: cancer-related death) according to BM... by Yukitoshi Sakao (2547880)

Subjects:

Downregulation of G9a induces autophagy and decreases tumorigenicity in neuroblastoma cells. by Xiao-Xue Ke (626989)

Overview of the six original ACTIV-3/TICO trials. by Elizabeth S. Munroe (21568166)

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…We describe the discovery of a thioester-containing glucocorticoid receptor modulator (GRM) payload and the corresponding antibody–drug conjugate (ADC). …”

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…We describe the discovery of a thioester-containing glucocorticoid receptor modulator (GRM) payload and the corresponding antibody–drug conjugate (ADC). …”

Image 5_Deciphering the oncogenic network: how C1QTNF1-AS1 modulates osteosarcoma through miR-34a-5p and glycolytic pathways.tif by Yu Zhang (12946)

“…</p>Discussion<p>Our research emphasizes the critical role of C1QTNF1-AS1 in the pathogenesis of osteosarcoma (OS). We discovered that the downregulation of C1QTNF1-AS1 indirectly upregulates the expression of LDHA and PDK3 by suppressing miR-34a-5p, which functions as a regulator of the Warburg effect. …”

Table 5_Deciphering the oncogenic network: how C1QTNF1-AS1 modulates osteosarcoma through miR-34a-5p and glycolytic pathways.doc by Yu Zhang (12946)

“…</p>Discussion<p>Our research emphasizes the critical role of C1QTNF1-AS1 in the pathogenesis of osteosarcoma (OS). We discovered that the downregulation of C1QTNF1-AS1 indirectly upregulates the expression of LDHA and PDK3 by suppressing miR-34a-5p, which functions as a regulator of the Warburg effect. …”

Protective Effect of Remote Limb Ischemic Perconditioning on the Liver Grafts of Rats with a Novel Model by Junjun Jia (704682)

“…</p><p>Conclusion</p><p>In conclusion, we successfully established a novel model of RIC in rat LT, the optimal RIC 5min*3 algorithm seemed to be more efficient to alleviate IRI of the liver graft in both functional and morphological categories, which due to its antioxidative, anti-inflammation activities and activating PI3K Akt pathway.…”

Fig 2A–2C and 2G–2L Data. by Kevin D. Gaitonde (15411707)

“…We observed a marked decrease in nocturnal locomotion of <i>Opn5</i>^<i>cre</i><i>; Gnas</i>^<i>fl/fl</i> mice at both 28°C and 22°C, but no overall differences in energy expenditure, respiratory exchange, or food and water consumption. …”

MicroRNA expression profile in retina and choroid in oxygen-induced retinopathy model by Michel Desjarlais (6832442)

“…During OIR-induced vessel degeneration phase, miR-199a-3p, -199a-5p, -1b, -126a-3p displayed a robust decreased expression (> 85%) in the retina. …”

AM induces decreased contrast detection performance. by Nathalie Van Humbeeck (3270255)

The sample of students across ten introductory biology courses who took exams and either had a measure of prior demonstrated academic ability (ACT) that we could obtain from their... by Cissy J. Ballen (3846940)

Relative <i>APOBEC3A</i> and MeV <i>M</i> mRNA quantification upon MeV infections in cells stably expressing DNase I. by Pierre Khalfi (7868252)

The Deoxyhypusine Synthase Mutant <i>dys1-1</i> Reveals the Association of eIF5A and Asc1 with Cell Wall Integrity by Fabio Carrilho Galvão (396804)

“…In this study, we generated and characterized the <i>dys1-1</i> mutant, which showed a strong depletion of mutated Dys1 protein, resulting in more than 2-fold decrease in hypusine levels relative to the wild type. …”

CICR in NG2 cells. by Christian Haberlandt (226735)

“…Traces represent the average of 5 cells. (B) Single pulses (gray box, lower trace) induced [Ca²⁺]_i elevations that were sensitive to thapsigargin (1 µM, elevation decreased to 10%) indicating a contribution of Ca²⁺-release from intracellular stores. …”

Significantly decreased adhesion to host cells by the Δ<i>tad123</i> mutant (A) and time-dependent recovery (B). by Tra-My Duong-Nu (7300970)

Lipid Droplet-Binding Protein TIP47 Regulates Hepatitis C Virus RNA Replication through Interaction with the Viral NS5A Protein by Dorothee A. Vogt (247917)

“…To identify host proteins that interact with NS5A, we performed a yeast two-hybrid screen with the N-terminus of NS5A (amino acids 1–31), a well-studied α-helical domain important for the membrane tethering of NS5A. …”

Effects of Nogo-A and its receptor on the repair of sciatic nerve injury in rats by Junjie Jiang (7255706)

Magnification X2 of Fig 4A. by Huan W. Yang (19746645)

“…<i>intracellularis</i> infection. In this study, we investigated the nuclear factor-<b>κ</b>B (NF-κB)-regulated immune response against infection of a clinical strain Dkp23 and a live-attenuated Enterisol vaccine strain in PK-15 cells. …”

SPSB2 inhibits hepatitis C virus replication by targeting NS5A for ubiquitination and degradation by Mingzhen Wang (7042184)

“…Additionally, we demonstrated that SPSB2 interacted with HCV structural protein E1 and nonstructural protein protein 5A (NS5A) via the C-terminal portion of the SPSB2 SPRY domain. …”