Genome wide decrease of DNA replication eye density at the midblastula transition of <i>Xenopus laevis</i> by Marie Platel (750508)

“…S phase is very rapid in early embryos, about 20–30 times faster than in differentiated cells. Using a combination of DNA fiber studies and a <i>Xenopus laevis</i> embryonic <i>in vitro</i> replication system, we show that S phase slows down shortly after the MBT owing to a genome wide decrease of replication eye density. …”

An autophagy-inducing compound ML246 reduces amyloid load in an autophagy-dependent manner in vitro and in vivo. by Altea Rocchi (3278457)

Supplementary Material for: Optimizing Cerebral Autoregulation May Decrease Neonatal Regional Hypoxic-Ischemic Brain Injury by Lee J.K. (3588656)

Fluoxetine decreases TOPFlash firefly luciferase reporter activity. by Kentaro Miyamoto (123271)

Scaling Laws for the Influence of Gravity and Its Gradient on Dropwise Condensation: A Simulation Study by Chen Ma (714759)

“…We also identify a critical gravitational acceleration determined by nucleation density, above which a counterintuitive trend emerges: the heat flux decreases with increasing gravitational acceleration. …”

Scaling Laws for the Influence of Gravity and Its Gradient on Dropwise Condensation: A Simulation Study by Chen Ma (714759)

“…We also identify a critical gravitational acceleration determined by nucleation density, above which a counterintuitive trend emerges: the heat flux decreases with increasing gravitational acceleration. …”

Phenotypic deficits in the HIV-1 envelope are associated with the maturation of a V2-directed broadly neutralizing antibody lineage by Lucia Reh (546554)

“…To enable this, properties that render HIV-1 envelopes (Env) capable of eliciting bnAb responses need to be defined. Here, we followed the evolution of the V2 apex directed bnAb lineage VRC26 in the HIV-1 subtype C superinfected donor CAP256 to investigate the phenotypic changes of the virus populations circulating before and during the early phases of bnAb induction. …”

datasheet1_Allopregnanolone Decreases Evoked Dopamine Release Differently in Rats by Sex and Estrous Stage.docx by Ana Paula S. Dornellas (9983996)

“…As allopregnanolone is a potent positive allosteric modulator of GABA_A receptors, and GABA_A receptors can regulate dopamine release, we hypothesized that allopregnanolone would reduce phasic fluctuations in mesolimbic dopamine release that are important in learning and reward processing. …”

Supplementary file 1_Role and mechanism of IGFBP5 in the real-ambient particulate matter exposure-induced chronic lung injury.docx by Ningning Chen (509273)

“…Moreover, microRNAs (miRNAs) are an important class of gene expression regulators. We found that the upregulated hsa-miR-33a-5p repressed IGFBP5 translation by forming a silencing complex with Argonaute protein 2 (AGO2) in a real-ambient PM exposure system, which further led to the suppression of the ERK1/2-SOD2 signaling pathway and increased levels of ROS.…”

Decreased alveolar levels of TNF-α and IL-6R levels in ADAM17-null mice. by Patrick G. Arndt (351620)

Summary plot for the effect of important food sources of fructose-containing sugars on diastolic blood pressure (DBP). by Qi Liu (33068)

PGRN deletion decreased the susceptibility to invasive <i>C</i>.<i>albicans</i> infection in mice. by Jiayu Liu (3951515)

Elevated Level of Wnt5a Protein in Localized Prostate Cancer Tissue Is Associated with Better Outcome by Azharuddin Sajid Syed Khaja (199670)

“…In vitro, we demonstrated that recombinant Wnt5a decreased invasion of 22Rv1 and DU145 cells and that siRNA knockdown of endogenous Wnt5a protein led to increased invasion of 22Rv1 and LNCaP cells.…”

Autophagosomal sequestration of Aβ42 in brain of autophagy-hyperactive mice. by Altea Rocchi (3278457)

Decreased CD39 protein expression by islet resident macrophages heralds T1D in NOD mice. by Thomas B. Thornley (2550766)

Summary plot for the effect of important food sources of fructose-containing sugars on systolic blood pressure (SBP). by Qi Liu (33068)

DataSheet_1_microRNA-144/451 decreases dendritic cell bioactivity via targeting interferon-regulatory factor 5 to limit DSS-induced colitis.pdf by Zhijie Lin (173992)

“…Thus, our results reveal a novel miR144/451-IRF5 pathway in DCs that protects experimental colitis. …”

Rac1 activity rapidly decreases upon cell-cell adhesion in 3-D cell aggregates. by Khameeka N. Kitt (227731)

“…High levels of active Rac1 at 0 minutes rapidly decreased (∼66%) within 5 minutes of cell-cell adhesion, and declined to a baseline level by 30 minutes (A). …”

Data Sheet 1_Probiotic Limosilactobacillus reuteri KUB-AC5 decreases urothelial cell invasion and enhances macrophage killing of uropathogenic Escherichia coli in vitro study.pdf by Arishabhas Tantibhadrasapa (13929639)

“…The human bladder epithelial cell line UM-UC-3 was used to assess the adhesion and pathogen-attachment inhibition properties of AC5 on UPEC.</p>Results and discussion<p>Our data showed that AC5 can attach to UM-UC-3 and decrease UPEC attachment in a dose-dependent manner. …”

<i>Becn1</i>^F121A leads to autophagy hyperactivation in vivo. by Altea Rocchi (3278457)