TPCA-1 inhibits NF-κB signaling pathway and the thermal injury-induced angiogenesis-associated factors. by Huayi Lu (424662)

“…<p>(A) TPCA-1 inhibits the TNFα-induced κB-Luciferase activity in a dosage dependent manner. 293T cells containing κB-Luciferase reporter were pretreated with or without TPCA1 for 30 minutes, then stimulated with 10 ng/mL TNFα to induce κB-Luciferase expression in the presence of the indicated amount of TPCA-1 for 5 hours, and followed by cell lysis and luciferase assay. …”

Abl kinases are activated in Met-driven mouse mammary tumors and inhibition of Abl kinases suppresses HGF-induced migration and invasion of breast cancer cells. by Ran Li (57928)

“…***P<0.001; **P<0.01; *P<0.05. Error bars represent mean (n = 3) ± S.E.M. (D-E) HGF-induced breast cancer cell invasion was decreased by Abl kinase inhibitors. …”

Supplementary Material for: The Cost of Persistent Asthma in Europe: An International Population-Based Study in Adults by Accordini S. (4121878)

“…<b><i>Results:</i></b> The mean total cost per patient was EUR 1,583 and was largely driven by indirect costs (i.e. lost working days and days with limited, not work-related activities 62.5%). …”

Prolonged Ethanol Exposure Increases Nucleoside Uptake Activity of ENT1-216Thr Compared to ENT1-216Ile. by Jeong-Hyun Kim (6973)

“…The substitution of 216Ile to 216Thr showed decreased hydrophobicity by 5.2 using Kyte-Doolittle scale (4.5 vs. −0.7) and increased hydrophilicity by 1.4 using Hopp-Woods scale (−1.8 vs. −0.4). …”

TRPM8 acting as comparator of temperature. by Koji Tajino (355302)

“…When temperature (<i>T</i>) was decreased slowly from 38 to 10°C (B), activities (output, <i>y</i>) of TRPM8 appeared at threshold temperature (28.4±0.5°C, mean ± SEM; n = 5) and increased with a fall in temperature. …”

The Fuglevand model can overestimate the contribution of motor noise to force variability. by Akira Nagamori (4743981)

“…F) CoV of force for the entire population as a function of mean force levels. …”

AA quantitatively affects mESC neuronal differentiation and maintains pluripotency. by Sandro L. Pereira (491558)

“…TuJ1 expression consistently decreased in cells treated with AA starting on day 2, 5 and 8 on both cell lines (A). …”

Observed water repellency in undecomposed and decomposed leaf litter. by Gaspare Cesarano (686639)

“…Plant litter species are ranked by decreasing difference between undecomposed and decomposed materials (significantly highest means within each plant litter species: *, <i>P</i> < 0.05, Tukey's HSD post-hoc test from the GLMM in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0152565#pone.0152565.s003" target="_blank">S2 Table</a>).…”

SKF96365 and 2-APB inhibit Src activation. by Mengchen Zou (725646)

“…<p>Representative immunoblots showing that SKF96365 (A) and 2-APB (B) decreased HMGB1-induced Src phosphorylation. …”

FHL2 silencing reduces lung metastasis in mice. by Julia Brun (286504)

“…Proposed model in which FHL2 silencing using shFHL2 in murine osteosarcoma cells attenuates Wnt/β-catenin signaling and reduces the expression of Wnt5a and Wnt10b and possibly other FHL2 target genes in the tumors, resulting in decreased osteosarcoma cell growth, invasiveness and tumorigenesis <i>in vivo</i> (D).…”

Western blot analysis of claudin-1 and occludin expression after apical treatment with TGFβs. by Angelika Stammler (483878)

“…<p>A: Western blot with lysates of MEPC5 after apical stimulation with TGFβ1, TGFβ2 or TGFβ3 compared to untreated cells. …”

For experimental data, too, recording length has little effect on estimated total history dependence, but larger impact on the estimated information timescale. by Lucas Rudelt (4059505)

“…Before taking the median over sorted units, for each unit we averaged estimates over 10 excerpts of the full recording, each with 3 or 5 minutes duration, and over 8,4 and 2 excerpts with 10, 20 and 45 minutes duration, respectively.…”

Time-course of mRNA expression of IGF-system genes and the activation levels of signalling mediators in the E18.8 cochlea. by Hortensia Sanchez-Calderon (186893)

“…<p>(<b>A–D</b>) mRNA expression levels of <i>Igf1</i>, <i>Igf1r</i>, <i>Igfbp2</i> and <i>Igfbp3</i> were analyzed by qRT-PCR in <i>Igf1^+/+</i> (open circles) and <i>Igf1^−/−</i> (closed circles) mice at E15.5 and E18.5 (n = 8), P5, P15, P30, P60 and P90 (n = 6). …”

Visualization of pathways, interacting network, and validation of selected downstream regulators. by Soumya Panigrahi (188599)

“…For CrkL, apoptin induced inhibition of Bcr-Abl phosphorylation lead to the down-regulation of CrkL resulting in lower phosphorytion indicating that apoptin decreases the activation of CrkL, a down-stream substrate of Bcr-Abl. …”

Identification and Functional Characterization of Novel Phosphorylation Sites in TAK1-Binding Protein (TAB) 1 by Alexander Wolf (191641)

“…It also enhances TAB1-dependent CCL5 secretion in response to IL-1 and increases activity of a post-transcriptional reporter gene, which contains the <em>CCL5</em> 3′ untranslated region. …”

Video_2_Plasma-Treated Water Affects Listeria monocytogenes Vitality and Biofilm Structure.WMV by Oliver Handorf (10713426)

“…<p>Background: Plasma-generated compounds (PGCs) such as plasma-processed air (PPA) or plasma-treated water (PTW) offer an increasingly important alternative for the control of microorganisms in hard-to-reach areas found in several industrial applications including the food industry. To this end, we studied the antimicrobial capacity of PTW on the vitality and biofilm formation of Listeria monocytogenes, a common foodborne pathogen.…”

Data_Sheet_1_EPS Glycoconjugate Profiles Shift as Adaptive Response in Anaerobic Microbial Granulation at High Salinity.PDF by Maria C. Gagliano (5472413)

“…Fluorescence lectin bar coding (FLBC) screening highlighted a significant shift in the glycoconjugate pattern between granules grown at 5 and 20 g/L of Na⁺, and the presence of different extracellular domains. …”

Video_1_Plasma-Treated Water Affects Listeria monocytogenes Vitality and Biofilm Structure.WMV by Oliver Handorf (10713426)

“…<p>Background: Plasma-generated compounds (PGCs) such as plasma-processed air (PPA) or plasma-treated water (PTW) offer an increasingly important alternative for the control of microorganisms in hard-to-reach areas found in several industrial applications including the food industry. To this end, we studied the antimicrobial capacity of PTW on the vitality and biofilm formation of Listeria monocytogenes, a common foodborne pathogen.…”

Functional Characteristics of the Naked Mole Rat μ-Opioid Receptor by Melanie Busch-Dienstfertig (490248)

Sorafenib enhanced expression of osteopontin, an AP-1 target gene, in human hepatoma cell lines. by Yuki Haga (764328)

“…<p>(A, B) Knockdown of c-Jun decreased expression of osteopontin after 48 hours of transfection into PLC/PRF/5 cells with siRNA against c-Jun (si-c-Jun) or si-control (si-C). …”