Functional and Transcriptional Induction of Aquaporin-1 Gene by Hypoxia; Analysis of Promoter and Role of Hif-1α by Irene Abreu-Rodríguez (193399)

“…Stopped-flow light-scattering experiments confirmed an increase in the water permeability of 9L cells exposed to hypoxia, supporting the view that hypoxic Aqp1 up-regulation has a functional role. To investigate the molecular mechanisms underlying this regulatory process, transcriptional regulation was studied by transient transfections of mouse endothelial cells with a 1297 bp 5′ proximal Aqp1 promoter-luciferase construct. …”

Accelerated Reendothelialization, Increased Neovascularization and Erythrocyte Extravasation after Arterial Injury in BAMBI^−/− Mice by Nicolas Guillot (156214)

“…The response to the TGFβ family of growth factors can be modified by BAMBI (BMP, Activin, Membrane Bound Inhibitor) acting as a non-signaling, competitive antagonist of TGFβ type I receptors such as ALK 1 and 5. …”

Presentation_1_Dietary Oxalate Loading Impacts Monocyte Metabolism and Inflammatory Signaling in Humans.pptx by Parveen Kumar (428921)

“…Increased consumption of meals with high oxalate content may stimulate urinary calcium oxalate (CaOx) crystals, which are precursors to CaOx kidney stones. We previously reported that CaOx stone formers have decreased monocyte cellular bioenergetics compared to healthy participants and oxalate reduces monocyte metabolism and redox status in vitro. …”

Quantitative Proteomic Analysis of Niemann-Pick Disease, Type C1 Cerebellum Identifies Protein Biomarkers and Provides Pathological Insight by Stephanie M. Cologna (125652)

“…A subset of NPC1 patients on miglustat, a glycosphingolipid synthesis inhibitor, showed significantly decreased levels of FABP3 compared to patients not on miglustat therapy. …”

Table_1_Plasma Oxidized Albumin in Acute Ischemic Stroke Is Associated With Better Outcomes.DOCX by Leonard T. Rael (6901913)

“…For every 1% increase in %OxHSA, the odds of a favorable discharge mRS increased 11%. The odds of a favorable discharge mRS decreased 18% for every 1-point increase in the initial NIHSS.…”

Data_Sheet_1_Fatigue Induced by Repeated Changes of Direction in Élite Female Football (Soccer) Players: Impact on Lower Limb Biomechanics and Implications for ACL Injury Preventio... by Matteo Zago (5721068)

“…Knee extension moment decreased in 8, knee valgus moment increased in 5 players. …”

Latency to feed during the novelty-induced suppressed feeding test (NSFT). by Barbara Baldo (500513)

“…A, B. In females, BACHD-SF1 mice recorded a decreased latency to eat in the novel environment compared to WT controls but there were no differences in the male group across the genotypes. …”

Loss of <i>Dlg-1</i> in the Mouse Lens Impairs Fibroblast Growth Factor Receptor Signaling by SungKyoung Lee (563448)

“…Herein, we asked if <i>Dlg-1</i> is a regulator of the Fibroblast growth factor receptor (Fgfr) signaling pathway, which is known to be required for fiber cell differentiation. …”

Data_Sheet_1_Soil bacteria are more sensitive than fungi in response to nitrogen and phosphorus enrichment.docx by Youchao Chen (312307)

“…However, it is still unclear on how bacterial and fungal communities would respond to the simultaneously increased N and P enrichment. In this study, we used a field experiment to simulate N and P input, and examined the effects of N and P additions on the abundance, alpha-diversity, and community composition of soil bacteria and fungi in a riparian forest. …”

Expression and prognostic impact of matrix metalloproteinase-2 (MMP-2) in astrocytomas by Rahimsan K. Ramachandran (3778768)

“…We found a positive correlation between MMP-2 and tissue inhibitor of metalloproteinases-1 (TIMP-1), and combined MMP-2 and TIMP-1 had stronger prognostic value than MMP-2 alone also when adjusting for age and gender (HR 2.78; 95% CI 1.30–5.92; p = 0.008). …”

Screen candidates modify the expression of RAS/MAPK components. by Dariel Ashton-Beaucage (538989)

“…Results were similar to those in cell culture qPCR experiments in (A): <i>CG1603</i> RNAi caused a reduction in <i>mapk</i> levels (−2.06; <i>p</i>-value, 5.3×10⁻⁴), <i>gfzf</i> RNAi reduced <i>mek</i> levels (−1.66; <i>p</i>-value, 5.4×10⁻⁴), and <i>CG4936</i> reduced <i>PTP-ER</i> levels (−1.06; <i>p</i>-value, 5.7×10⁻⁴). …”

DataSheet4_Saikosaponin D Inhibits Peritoneal Fibrosis in Rats With Renal Failure by Regulation of TGFβ1/ BMP7 / Gremlin1/ Smad Pathway.xls by Liu Ruiqi (11511985)

“…To this aim, we used a model 5/6 nephrectomy and peritoneal fibrosis in rats. …”

DataSheet2_Saikosaponin D Inhibits Peritoneal Fibrosis in Rats With Renal Failure by Regulation of TGFβ1/ BMP7 / Gremlin1/ Smad Pathway.xls by Liu Ruiqi (11511985)

“…To this aim, we used a model 5/6 nephrectomy and peritoneal fibrosis in rats. …”

Supplementary file 1_Quantitative microbial taxonomy across particle size, depth, and oxygen concentration.zip by Paulina Huanca-Valenzuela (21414911)

“…</p>Methods<p>In this study, we quantified microbial diversity using a fractionation method that separated particles into seven fine scale fractions (0.2–1.2, 1.2–5, 5–20, 20–53, 53–180,180–500, >500 μm), and included a spike-in standard for sequencing the 16S rRNA gene. …”

DataSheet3_Saikosaponin D Inhibits Peritoneal Fibrosis in Rats With Renal Failure by Regulation of TGFβ1/ BMP7 / Gremlin1/ Smad Pathway.xls by Liu Ruiqi (11511985)

“…To this aim, we used a model 5/6 nephrectomy and peritoneal fibrosis in rats. …”

DataSheet4_Saikosaponin D Inhibits Peritoneal Fibrosis in Rats With Renal Failure by Regulation of TGFβ1/ BMP7 / Gremlin1/ Smad Pathway.xls by Liu Ruiqi (11511985)

“…To this aim, we used a model 5/6 nephrectomy and peritoneal fibrosis in rats. …”

DataSheet6_Saikosaponin D Inhibits Peritoneal Fibrosis in Rats With Renal Failure by Regulation of TGFβ1/ BMP7 / Gremlin1/ Smad Pathway.xls by Liu Ruiqi (11511985)

“…To this aim, we used a model 5/6 nephrectomy and peritoneal fibrosis in rats. …”

DataSheet6_Saikosaponin D Inhibits Peritoneal Fibrosis in Rats With Renal Failure by Regulation of TGFβ1/ BMP7 / Gremlin1/ Smad Pathway.xls by Liu Ruiqi (11511985)

“…To this aim, we used a model 5/6 nephrectomy and peritoneal fibrosis in rats. …”

DataSheet2_Saikosaponin D Inhibits Peritoneal Fibrosis in Rats With Renal Failure by Regulation of TGFβ1/ BMP7 / Gremlin1/ Smad Pathway.xls by Liu Ruiqi (11511985)

“…To this aim, we used a model 5/6 nephrectomy and peritoneal fibrosis in rats. …”

DataSheet7_Saikosaponin D Inhibits Peritoneal Fibrosis in Rats With Renal Failure by Regulation of TGFβ1/ BMP7 / Gremlin1/ Smad Pathway.xls by Liu Ruiqi (11511985)

“…To this aim, we used a model 5/6 nephrectomy and peritoneal fibrosis in rats. …”