Dicarbonyl stress, protein glycation and the unfolded protein response by Rabbani, Naila

“…We propose that dicarbonyl stress, through increased formation of MG-glycated proteins, may be an important physiological stimulus of the UPR and Glo1 inducers may provide a route to effective suppression and therapy. …”
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The effects of oxygen concentration on in vitro output of prostaglandin E2 and interleukin-6 from human fetal membranes. by Al-Asmakh, Maha

“…The main sources are the fetal membranes, including the amnion, chorion and decidua, and it is well established that stimuli [bacteria, bacterial endotoxins, interleukin (IL)-1beta, corticotrophin releasing hormone and platelet activating factor], as well as negative regulators (progesterone and IL-10), control the net output of PGs and cytokines in vitro. In this study, we have investigated the effect of oxygen tension on fetal membrane biology, as a reconsideration of the literature suggests that fetal membranes are normally exposed to approximately 3% O(2) (approximately 20 mmHg) in vivo, rather than the 20% O(2) (150 mmHg) used for in vitro culture. …”
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Cry1Ac toxicity enhancement towards lepidopteran pest Ephestia kuehniella through its protection against excessive proteolysis by Elleuch, Jihen

“…However, the widespread use of B. thuringiensis δ-endotoxins has often been challenged by a lack of understanding of the target insect physiology as well as its midgut biochemistry.In the present investigation, we have evidenced and explained the toxicity improvement of Cry1Ac δ-endotoxins against Ephestia kuehniella larvae through in vivo combination with P20 helper protein. …”
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Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer by Ashour, Amal

“…Results In high glucose concentration cultures, there was a ca. twofold increase in cellular MG, cellular protein MG-H1 content and decreased attachment of PDLFs to collagen-I. …”
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Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model by Abou-Saleh, Haissam

“…Although the observed toxic effect failed to affect embryo survival, whether a prolonged ChNP treatment may induce other potentially harmful effects remains to be elucidated. …”
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Specific bioactive compounds in ginger and apple alleviate hyperglycemia in mice with high fat diet-induced obesity via Nrf2 mediated pathway by Sampath, Chethan

“…Phloretin and [6]-gingerol also decreased the levels of AGEs and CML levels, via Nrf2 pathway, enhancing GSH/GSSG ratio, heme oxygenase-1 and glyoxalase 1 in liver tissue. …”
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Reduced vasorin enhances angiotensin II signaling within the aging arterial wall by Pintus, Gianfranco

“…Angiotensin II (Ang II) amplifies TGF-β1 activation in the VSMCs of the arterial wall with aging. In this study, we hypothesized that a reduced expression of the protein vasorin plays a contributory role in magnifying Ang II-associated fibrogenic signaling in the VSMCs of the arterial wall with aging. …”
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Pore networks to characterize formation damage due to fines at varied confinement and sand shape by Hannun, J.

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Correlations between Resting Electrocardiogram Findings and Disease Profiles: Insights from the Qatar Biobank Cohort by Qafoud, Fatima

“…Background: Resting electrocardiogram (ECG) is a valuable non-invasive diagnostic tool used in clinical medicine to assess the electrical activity of the heart while the patient is resting. …”
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Climatic Aridity Gradient Modulates the Diversity of the Rhizosphere and Endosphere Bacterial Microbiomes of Opuntia ficus-indica by Karray, Fatma

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Machine learning-based management of electric vehicles charging: Towards highly-dispersed fast chargers by Shibl, M.

“…Additionally, LSTM was also the model with the smallest error rate, at a value of ±0.7%, followed by RF, DT, KNN, SVM, DNN, and NB. …”
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Ratings of perceived exertion misclassify intensities for sedentary older adults during graded cycling test: Effect of supramaximal high-intensity interval training by Jabbour G.

“…Two healthy groups of 17 young adults [average (SD) age: 26.2 (2.4) year] and 13 older adults [average (SD) age: 54.5 (2.3) year] completed a 6-week SCE intervention on an ergocycle. …”
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Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling by Ghantous, Crystal M.

“…Mechanically stretching the RPV significantly decreased APN protein expression after 24 hours and APN mRNA expression in a time-dependent manner in VSMCs. …”
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From the Renewed Policy of Sport Mega Events to Prosumerism: Articulating the challenges faced by the 2022 FIFA World Cup in Qatar by Bretherton, Paul

“…These changes in the bidding and organisation of SMEs can be seen as examples of prosumerism, which refers to "the tendency towards a market where the distinction between producers and consumers decreases, where consumers are producing their own goods and services" (IGI Global, 2022, para. 2). …”
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Pore-scale simulation of fine particles migration in porous media using coupled CFD-DEM by Elrahmani, Ahmed

“…In this work, we present a coupled computational fluid dynamics-discrete element method (CFD-DEM) based modelling framework that is capable of simulating the migration of a large number of fine particles, on the colloids size through physically realistic porous media. …”
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Independent and combined effects of antioxidant supplementation and circuit resistance training on selected adipokines in postmenopausal women by Saeidi, Ayoub

“…We examined the effects of the independent and combined effects of Zataria Multiflora supplementation and circuit resistance training (CRT) on selected adipokines among postmenopausal women. …”
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Phospholipase C zeta profiles are indicative of optimal sperm parameters and fertilisation success in patients undergoing fertility treatment. by Kashir, Junaid

“…Male recruitment criteria required a minimum sperm count of 5 × 10 spermatozoa/mL, while all female patients included in this study yielded at least five oocytes for treatment. …”
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Investigating algal CO2 capture through screening of Qatari desert microalgae & cyanobacteria strains by Al Muraikhi, Mariam

“…A number of different trends in CO2 tolerance could be identified from the results; a number of strains showed a clear inhibition of growth with CO2 concentrations of 5% and higher, whilst others showed increasing growth rates for increasing CO2 concentrations up to 30%. …”
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Biocompatibility and toxicity of novel iron chelator Starch-Deferoxamine (S-DFO) compared to zinc oxide nanoparticles to zebrafish embryo: An oxidative stress based apoptosis, phys... by Nasrallah, Gheyath

“…Although its efficacy was established in one small cohort clinical trial, its potential adverse effect was not adequately addressed. We utilized zebrafish model to assess S-DFO toxicity using following assays: mortality, teratogenicity, hatching rate, tail flicking, Acridine Orange staining for apoptosis detection, o-dianisidine staining for hemoglobin synthesis, and the level of Hsp70 as a general stress indicator. …”
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Dynamic Distributed Multi-Path Aided Load Balancing for Optical Data Center Networks by Wang, Fu

“…This paper establishes a leaf-spine Hoe-DCN model to illustrate the principal characteristic of dynamic load balancing in TOR switches for the first time. …”
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