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Hemodiafiltration Decreases Serum Levels of Inflammatory Mediators in Severe Leptospirosis: A Prospective Study
Published 2016“…We previously demonstrated that early initiation of sustained low-efficiency dialysis (SLED) followed by daily SLED significantly decreases mortality. …”
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Macroscopic and histological assessment of colic tumor and inflammation in mice.
Published 2020Subjects: -
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Statistically significant correspondence between human psoriasis and mouse psoriasiform phenotypes: Proportion of psoriasiform-increased to psoriasiform-decreased transcripts.
Published 2011“…<p>Genes significantly increased or decreased in human psoriasis were identified and the expression of orthologous genes was studied in the K5-Tie2 phenotype (A and B), the IMQ phenotype (C and D), the K14-AREG phenotype on ear skin (E and F), the K14-AREG phenotype on tail skin (G and H), the K5-Stat3C phenotype (I and J), and the K5-TGFβ1 phenotype (K and L). …”
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Effect of iron mining tailings as a red ceramic additive for decreased sintering temperature
Published 2021“…We produced test pieces including a mixture of soil with 10 and 20% content of waste exposed to the sintering process at temperatures of 750, 850 and 950° C. …”
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Breast Cancer 1 (BrCa1) May Be behind Decreased Lipogenesis in Adipose Tissue from Obese Subjects
Published 2012“…Consistent with its role limiting fatty acid biosynthesis, both <em>BrCa1</em> mRNA (3.5-fold, p<0.0001) and protein (1.2-fold, p = 0.001) were increased in pre-adipocytes, and decreased during <em>in vitro</em> adipogenesis, while P-ACC decreased during differentiation of human adipocytes (p = 0.005) allowing lipid biosynthesis. …”
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Aquaporin 2 Mutations in <i>Trypanosoma brucei gambiense</i> Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol
Published 2013“…The identified mutant <i>T. b. gambiense</i> are 40- to 50-fold less sensitive to pentamidine and 3- to 5-times less sensitive to melarsoprol than the reference isolates. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Statins Decrease Neuroinflammation and Prevent Cognitive Impairment after Cerebral Malaria
Published 2012“…In addition to their effects on the inhibition of cholesterol synthesis, statins have pleiotropic immunomodulatory activities. Here we tested if statins would prevent cognitive impairment in a murine model of cerebral malaria. …”
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Development of Selective and Soluble Mitochondrial Complex 1 Inhibitors Derived from Papaverine for Radiosensitization of Cancer
Published 2025“…We have therefore generated additional derivatives which have improved mitochondrial complex 1 inhibition and reduced PDE10A inhibition. …”