Synthesis and Pharmacological Evaluation of Different Piperine Analogs for Therapeutic Potential to Prevent ER Stress حسب Hammad, Ayat Samir

"…Our findings indicate that exposure to tunicamycin (0.5 µg/mL) for 2 hours induces the expression of GRP78 and CHOP, and causes a significant reduction in renal cell viability. …"
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Metabolic consequences of obesity on the hypercoagulable state of polycystic ovary syndrome. حسب Moin, Abu Saleh Md

"…We determined plasma coagulation pathway protein levels in PCOS (n = 146) and control (n = 97) women recruited to a PCOS biobank. …"
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New genetic insights into improving barley cope with salt stress via regulating mineral accumulation, cellular ion homeostasis, and membrane trafficking حسب Samar G., Thabet

"…This study was designed to explore the natural variation of responsive physiological and agronomic traits in a diverse spring barley panel under salt-affected soil and the application of selenium nanoparticles (Se-NP) during the vegetative phase. …"
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In vitro and in vivo inhibition of aldose reductase and advanced glycation end products by phloretin, epigallocatechin 3-gallate and [6]-gingerol حسب Sampath, Chethan

"…High glucose induced toxicity decreased cell viability compared to the untreated cells and AR activity increased to 2–5 folds from 24 to 96h. …"
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Electrochemical behavior of mild and corrosion resistant concrete reinforcing steels حسب Sohail, Muazzam G.

"…The polarization resistance of the HC was found to be 1.5 times higher than that of the MS. The EIS technique showed that EC, even with damaged epoxy coating, has the highest resistance to chloride attack. …"
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Western and ketogenic diets in neurological disorders: can you tell the difference? حسب Habashy, Karl John

"…Here, we discuss the principles of brain metabolism with a focus on the distinct effects of the Western and ketogenic diets on the progression of neurological diseases such as epilepsy, Parkinson's disease, Alzheimer's disease, and traumatic brain injury, highlighting the need to further explore the potential therapeutic effects of the ketogenic diet and the importance of standardizing dietary formulations to assure the reproducibility of clinical trials.…"
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Green Revolution dwarfing Rht genes negatively affected wheat floral traits related to cross-pollination efficiency حسب Schierenbeck, Matías

"…Anthers extrusion decreased from 40% (rht) to 20% (Rht1 and Rht2), 11% (Rht3), 8.3% (Rht1 + 2), and 6.5% (Rht2 + 3). …"
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Occurrence, origin and potential ecological risk of dissolved polycyclic aromatic hydrocarbons and organochlorines in surface waters of the Gulf of Gabès (Tunisia, Southern Mediter... حسب Hatem, Zaghden

"…The results demonstrated a wide range of concentrations (ng L−1) with the following decreasing order: Ʃ16 PAHs (17.6–71.2) > Ʃ20 PCBs (2.9–33.7) > Ʃ6 DDTs (1.1–12.1) > Ʃ4 HCHs (1.1–14.8). …"
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Ziziphus nummularia attenuates the malignant phenotype of human pancreatic cancer cells: Role of ros حسب Mesmar, J.

"…In addition, ZNE significantly decreased the migratory and invasive capacity of Capan-2 with a concomitant downregulation of integrin α2 and increased cell–cell aggregation. …"
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Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank حسب Al-Hamdani, Mohammed

"…However, BMD measures significantly contributed to predicting stiffness after controlling for sociodemographic variables (R2 = 0.065, ΔF(7, 1724) = 3.34, p = 0.002), with a higher total body BMD associated with increased stiffness and a higher trunk BMD associated with decreased stiffness. …"
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Antibacterial Performance of Protonated Polyaniline-Integrated Polyester Fabrics حسب Aizamddin, Muhammad Faiz

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Investigation of gas-liquid flow using electrical resistance tomography and wavelet analysis techniques for early kick detection حسب Barooah, Abinash

"…An increase in the liquid flow rate and eccentricity by 60% and 30% decreased the gas volume fraction by an average of 32.8% and 5.9% respectively, whereas an increase in the inclination by 80 increased the gas volume fraction by an average 42%. …"
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The impacts of water level fluctuations from paddy fields and aquaculture ponds on wetland habitats for wintering waterbirds: Implications for wetland management حسب Cheng, Bo

"…Based on remote sensing image data and hydrological data, we selected Caizi Lake as a study site and comparatively analyzed the changes in wintering waterbird habitats in a water level sequence under the two scenarios. …"
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Dicarbonyl stress, protein glycation and the unfolded protein response حسب Rabbani, Naila

"…We propose that dicarbonyl stress, through increased formation of MG-glycated proteins, may be an important physiological stimulus of the UPR and Glo1 inducers may provide a route to effective suppression and therapy. …"
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The effects of oxygen concentration on in vitro output of prostaglandin E2 and interleukin-6 from human fetal membranes. حسب Al-Asmakh, Maha

"…The main sources are the fetal membranes, including the amnion, chorion and decidua, and it is well established that stimuli [bacteria, bacterial endotoxins, interleukin (IL)-1beta, corticotrophin releasing hormone and platelet activating factor], as well as negative regulators (progesterone and IL-10), control the net output of PGs and cytokines in vitro. In this study, we have investigated the effect of oxygen tension on fetal membrane biology, as a reconsideration of the literature suggests that fetal membranes are normally exposed to approximately 3% O(2) (approximately 20 mmHg) in vivo, rather than the 20% O(2) (150 mmHg) used for in vitro culture. …"
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Cry1Ac toxicity enhancement towards lepidopteran pest Ephestia kuehniella through its protection against excessive proteolysis حسب Elleuch, Jihen

"…However, the widespread use of B. thuringiensis δ-endotoxins has often been challenged by a lack of understanding of the target insect physiology as well as its midgut biochemistry.In the present investigation, we have evidenced and explained the toxicity improvement of Cry1Ac δ-endotoxins against Ephestia kuehniella larvae through in vivo combination with P20 helper protein. …"
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Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer حسب Ashour, Amal

"…Results In high glucose concentration cultures, there was a ca. twofold increase in cellular MG, cellular protein MG-H1 content and decreased attachment of PDLFs to collagen-I. …"
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Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model حسب Abou-Saleh, Haissam

"…Although the observed toxic effect failed to affect embryo survival, whether a prolonged ChNP treatment may induce other potentially harmful effects remains to be elucidated. …"
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Specific bioactive compounds in ginger and apple alleviate hyperglycemia in mice with high fat diet-induced obesity via Nrf2 mediated pathway حسب Sampath, Chethan

"…Phloretin and [6]-gingerol also decreased the levels of AGEs and CML levels, via Nrf2 pathway, enhancing GSH/GSSG ratio, heme oxygenase-1 and glyoxalase 1 in liver tissue. …"
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Reduced vasorin enhances angiotensin II signaling within the aging arterial wall حسب Pintus, Gianfranco

"…Angiotensin II (Ang II) amplifies TGF-β1 activation in the VSMCs of the arterial wall with aging. In this study, we hypothesized that a reduced expression of the protein vasorin plays a contributory role in magnifying Ang II-associated fibrogenic signaling in the VSMCs of the arterial wall with aging. …"
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