R346K Mutation in the <i>Mu</i> Variant of SARS-CoV‑2 Alters the Interactions with Monoclonal Antibodies from Class 2: A Free Energy Perturbation Study by Filip Fratev (1799740)

“…The <i>Mu</i> variant of SARS-CoV-2 has been recently classified as a variant of interest (VOI) by the World Health Organization (WHO) but limited data are available at the moment. …”

<i>Furin</i> mutant hearts show a decreased in the number of phospo-Smad positive cells at the AV junction. by Laurent Dupays (2940330)

Data Sheet 1_Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank.pdf by Pia Leibold (21390134)

“…While some previous studies reported that CYP3A5 variants were associated with decreased blood pressure and risk of HTN, others reported no associations. …”

A Unique Modification of the Eukaryotic Initiation Factor 5A Shows the Presence of the Complete Hypusine Pathway in <em>Leishmania donovani</em> by Bhavna Chawla (176976)

“…<div><p>Deoxyhypusine hydroxylase (DOHH) catalyzes the final step in the post-translational synthesis of an unusual amino acid hypusine (<em>N</em>^€-(4-amino-2-hydroxybutyl) lysine), which is present on only one cellular protein, eukaryotic initiation factor 5A (eIF5A). We present here the molecular and structural basis of the function of DOHH from the protozoan parasite, <em>Leishmania donovani,</em> which causes visceral leishmaniasis. …”

ALK2 AON-induced exon skipping decreased BMP signaling in 2H11 endothelial cells. by SongTing Shi (430629)

The inhibitory effects of rosiglitazone and pioglitazone on the formation of functional osteoclasts on bone slices are significantly decreased in RANKL-pretreated BMMs. by Dongfeng Zhao (258868)

Supplementary Material for: Decrease of Hyperintense Vessels on Fluid-Attenuated Inversion Recovery Predicts Good Outcome in t-PA Patients by Sakuta K. (4147642)

“…HV scores (range 1-7) were evaluated according to Alberta Stroke Program Early Computed Tomography Score territories, and then by subtracting HV scores at 1 h after t-PA infusion from those on admission, with a result of >1 defined as decrease in HV score (DHV). …”

Transthyretin Amyloidosis: Chaperone Concentration Changes and Increased Proteolysis in the Pathway to Disease by Gonçalo da Costa (198731)

“…Our data shows that a complex network of extracellular chaperones are over represented in human plasma and we speculate that they act synergistically to cope with amyloid prone proteins. …”

Inhibition of Hsp90 abolished VEGF-mediated eNOS phosphorylation and decreased NO production and cell viability in BAECs. by Yuanzhuo Chen (802891)

Does the presence of exotic species decrease the initial development of native species in Brazilian seasonally dry tropical forests? by Carlos Leandro Costa Silva (12741450)

“…<div><p>ABSTRACT We assessed the impacts of the biological invasion of Azadirachta indica on the quality of plant species native to a Seasonally Dry Tropical Forest. …”

Colistin-phage combinations decrease antibiotic resistance in <i>Acinetobacter baumannii</i> via changes in envelope architecture by Xiaoqing Wang (514179)

Inhibition of HDAC6 activity decreased the levels of EGFR and increased acetyl-α-tubulin in renal epithelial cells. by Wei Liu (20030)

“…(C) and (D) Western blotting analysis of the expression of EGFR and acetyl-α-tubulin in <i>Pkd1</i> wild-type (WT) MEK cells (C) and <i>Pkd1^null/null</i> (Null) MEK cells (D) treated with or without TSA (100 ng/ml). TSA treatment decreased the levels of EGFR and increased the acetyl-α-tubulin in <i>Pkd1^null/null</i> (Null) MEK cells. …”

Impaired Telomere Maintenance and Decreased Canonical WNT Signaling but Normal Ribosome Biogenesis in Induced Pluripotent Stem Cells from X-Linked Dyskeratosis Congenita Patients by Bai-Wei Gu (740949)

“…Here we describe the production of iPS cells from DC patients with <i>DKC1 </i>mutations <i>Q31E</i>, <i>A353V </i>and <i>ΔL37</i>. …”

SDG decreases iron-induced oxidative stress in H9c2 cells. by Stephanie Puukila (568109)

The decrease in lactate induced by pyruvate is blocked by inhibition of MAS and of the TCA cycle in HKI/HKII double KD cells. by Scott John (228011)

“…Following the decrease in lactate evoked by pyruvate, addition of AOA reversed this effect, causing a rapid increase in lactate. …”

Inverse relation between I_basal and R_a arises from the decrease in Gα available for GIRK activation at higher I_basal. by Daniel Yakubovich (823436)

IFN-λ1 decreases miR-122 transcription through down regulation of HNF4α. by Fatma Aboulnasr (736868)

“…<p><b>(A and B)</b> S3-GFP and R4-GFP cells were treated either IFN-α (1000 I.U/mL) or IFN-λ (100ng/mL). …”

IL-4 Causes Hyperpermeability of Vascular Endothelial Cells through Wnt5A Signaling by Tom Skaria (2733439)

“…Our study identifies Wnt5A as a novel marker of IL-4 activated vascular endothelium and demonstrates a critical role for Wnt5A in mediating IL-4 induced endothelial barrier dysfunction. …”

Table_1_The Increase in Paraoxonase 1 Is Associated With Decrease in Left Ventricular Volume in Kidney Transplant Recipients.docx by Philip W. Connelly (10522333)

“…Restored kidney function through transplantation reduces left ventricular volume in both systole and diastole. We previously reported that the decrease in NT-proB-type natriuretic peptide (NT-proBNP) was associated with a decrease in adiponectin. …”

PDGF-BB maintains Bcl2/Bax ratio and decreases caspase-3 activation induced by Tat and morphine. by Shaily Malik (226661)

“…<p>(A) Human neurons were treated with 100 ng/ml Tat and/or 100 nM morphine for 12 hours with or without pre-treatment with 40 ng/ml PDGF-BB. …”