Aquaporin 2 Mutations in <i>Trypanosoma brucei gambiense</i> Field Isolates Correlate with Decreased Susceptibility to Pentamidine and Melarsoprol by Fabrice E. Graf (469055)

“…Here we describe two different kinds of <i>TbAQP2</i> mutations found in <i>T. b. gambiense</i> field isolates: simple loss of <i>TbAQP2</i>, or loss of wild-type <i>TbAQP2</i> allele combined with the formation of a novel type of <i>TbAQP2/3</i> chimera. …”

Kif2a accumulation at the base of <i>Ttbk2</i>^{<i>sca11/gt</i>} cilia causes instability. by Emily Bowie (543704)

data_sheet_1_The Reliance on Vestibular Information During Standing Balance Control Decreases With Severity of Vestibular Dysfunction.PDF by Joost van Kordelaar (5333498)

“…The vestibular weight during 0.5° peak-to-peak support surface rotations decreased with increasing spontaneous nystagmus eye velocity (ρ = −0.82, p < 0.001). …”

data_sheet_2_The Reliance on Vestibular Information During Standing Balance Control Decreases With Severity of Vestibular Dysfunction.PDF by Joost van Kordelaar (5333498)

“…The vestibular weight during 0.5° peak-to-peak support surface rotations decreased with increasing spontaneous nystagmus eye velocity (ρ = −0.82, p < 0.001). …”

Gas-Phase-like Inertial Rotation of a Platonic Solid in Reticular Amphidynamic Crystals of CUB-5: Molecular Dynamics and Experiment by Jing-Ran Shan (16641931)

“…Through quantum mechanical (QM) calculations and molecular dynamics (MD) simulations we verified that nearly barrierless cubane rotators in CUB-5 display rotational dynamics that transitions from continuous or inertial at high temperature, to chaotic behavior, and ultimately to discrete jumps, as the temperature decreases from room temperature down to cryogenic conditions. …”

Proteome-Wide Identification of Proteins and Their Modifications with Decreased Ambiguities and Improved False Discovery Rates Using Unique Sequence Tags by Yufeng Shen (239573)

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Discovery of Novel [1,2,4]Triazolo[1,5‑<i>a</i>]pyrimidine Derivatives as Novel Potent S‑Phase Kinase-Associated Protein 2 (SKP2) Inhibitors for the Treatment of Cancer by Kaizhao Hu (15670612)

“…Pharmacological inhibition of Skp2 has exhibited promising antitumor activity. Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-<i>a</i>]pyrimidine-based small molecules targeting Skp2. …”

Image_1_Increased Tumor Intrinsic Growth Potential and Decreased Immune Function Orchestrate the Progression of Lung Adenocarcinoma.pdf by Yue Zhao (186573)

Image_3_Increased Tumor Intrinsic Growth Potential and Decreased Immune Function Orchestrate the Progression of Lung Adenocarcinoma.pdf by Yue Zhao (186573)

Image_2_Increased Tumor Intrinsic Growth Potential and Decreased Immune Function Orchestrate the Progression of Lung Adenocarcinoma.pdf by Yue Zhao (186573)

Table_2_Increased Tumor Intrinsic Growth Potential and Decreased Immune Function Orchestrate the Progression of Lung Adenocarcinoma.docx by Yue Zhao (186573)

Table_1_Increased Tumor Intrinsic Growth Potential and Decreased Immune Function Orchestrate the Progression of Lung Adenocarcinoma.docx by Yue Zhao (186573)

Table_3_Increased Tumor Intrinsic Growth Potential and Decreased Immune Function Orchestrate the Progression of Lung Adenocarcinoma.xlsx by Yue Zhao (186573)

DataSheet_1_Increased circulating regulatory T cells and decreased follicular T helper cells are associated with colorectal carcinogenesis.docx by Qiao Meng (14368167)

A Single Amino Acid Deletion (ΔF1502) in the S6 Segment of Ca_V2.1 Domain III Associated with Congenital Ataxia Increases Channel Activity and Promotes Ca²⁺ In... by Maria Isabel Bahamonde (840859)

“…ΔF1502 strongly decreases the voltage threshold for channel activation (by ~ 21 mV), allowing significantly higher Ca²⁺ current densities in a range of depolarized voltages with physiological relevance in neurons, even though maximal Ca²⁺ current density through ΔF1502 Ca_V2.1 channels is 60% lower than through wild-type channels. …”

A randomized trial of a behavioral intervention to decrease hospital length of stay by decreasing bedrest by Juliana Tolles (8282265)

“…Previous studies of early mobilization have demonstrated improvement in outcomes, but the interventions studied have been resource-intensive. We aimed to decrease the time hospital inpatients spend in bed through a pragmatic mobilization protocol.…”