Design and Synthesis of Novel PET Radiotracers for Imaging Sphingosine-1-Phosphate Receptor 5 (S1PR5) in the Brain by Jiawen Lang (4288540)

Subjects:

Glucagon resistance and decreased susceptibility to diabetes in a model of chronic hyperglucagonemia by Nadejda Bozadjieva Kramer (9657179)

Optogenetic Recruitment of Dorsal Raphe Serotonergic Neurons Acutely Decreases Mechanosensory Responsivity in Behaving Mice by Guillaume P. Dugué (620333)

“…In behaving mice, the photostimulation of dorsal raphe serotonergic neurons produced a rapid and reversible decrease in the animals' responses to plantar stimulation, providing a new level of evidence that serotonin gates sensory-driven responses.…”

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

“…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC₅₀ = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”

Cortisone (500 nM, 24 h, black) and cortisol (500 nM, 24 h, dark grey) decrease lipogenesis in differentiated Chub-S7 cells. by Laura L. Gathercole (341979)

Estradiol decreased vanillin-induced responses in the ORNs of p5 mice. by Ninthujah Kanageswaran (683924)

“…<p>(A) Representative responses to 100 μM vanillin from Olfr73 positive ORNs in tissue slices were obtained from patch-clamp recordings set to a voltage-clamp configuration (V_h = -56 mV). …”

No significant sex differences in Iso-induced decrease of CaD₈₀. by Gregory S. Hoeker (650231)

“…B) Summary data for the decrease in CaD₈₀ (versus baseline values) as a function of the dose of Iso (1, 10, 31.6, 100, 316.2 nM) in the LV base <i>(left)</i> and apex <i>(right)</i> with pacing at 3 (<i>top</i>) and 5.5 Hz (<i>bottom</i>) for female (n = 5) and male (n = 5) hearts. …”

LPS dose-dependently decreases T cell proliferative response to OKT3. by Fanny Poujol (834338)

HC-070 decreases anxiety after CCK-4 treatment in an EPM. by Stefan Just (4811358)

S5 Data - by Ayuta Kishimoto (16814662)

“…On the other hand, the IC analysis showed a gradual decrease in chlorite ions in the acidic sodium chlorite solution. …”

At E9.5 Actb^−/− neural crest cells show a significant decrease of cadherin-11 expression. by Davina Tondeleir (426905)

“…We only observed a significant reduction of cadherin-11 intensities in Actb^−/− neural crest cells at E9.5. …”

HEWL interacts with dissipated oleic acid micelles, and decreases oleic acid cytotoxicity - Fig 1 by Qin Huang (49441)

Subjects:

Video5_Aging, not Parkinson’s disease, decreases a recalibration of body ownership caused by vision-respiratory interaction.MP4 by Daiki Shoji (18283906)

“…</p>Methods<p>By applying the rubber hand illusion (RHI), which temporarily alters ownership perception, and using a device that synchronizes the respiratory rhythm with the movement of a mannequin hand, we measured a change in ownership perception in RHI training by vision-respiratory interaction. …”

Table_1_FMT intervention decreases urine 5-HIAA levels: a randomized double-blind controlled study.DOCX by Lihong Wang (14991)

“…However, in the placebo group, GSRS, CARS, and SRS scores showed no significant changes, while ABC scores decreased from 72 to 58.75 (p = 0.034). The FMT group also showed a significant reduction in urinary 5-hydroxyindoleacetic acid (5-HIAA) levels from 8.6 to 7.32 mg/L (p = 0.022), while other metabolites showed no significant changes.…”

Image_5_Age-Dependent Decrease in the Induction of Regulatory T Cells Is Associated With Decreased Expression of RALDH2 in Mesenteric Lymph Node Dendritic Cells.TIF by Tomohiro Takano (9227690)

“…We examined Treg induction in young and aged mice using a Treg induction model by administering a food antigen, and we found that antigen-specific Treg induction was decreased in aged mice. …”

Overexpressions of the AB domain of RPA70 and the β-barrel domain of Ku70 significantly decrease HBoV1 replication in HAE-ALI. by Kang Ning (59789)

“…Duplex HBoV1 genome was loaded as a size marker (M) of 5.5 kb. …”

Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio by Jani Luukkonen (4339744)

“…The TRAcP 5B/5A ratio was decreased in RA and correlated negatively with the amount of phospho-OPN (p<0.05). …”

Bioavailable Soil Phosphorus Decreases with Increasing Elevation in a Subarctic Tundra Landscape by Andrea G. Vincent (543626)

“…We hypothesized that the concentration of labile P fractions would decrease with increasing elevation (and thus declining temperature), but would be lower in meadow than in heath, given that N to P ratios in meadow foliage are higher. …”

Pendrin gene ablation increases force/cross-sectional area and decreases thickness of the aorta. by Roy L. Sutliff (485240)