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we decrease » _ decrease (Expand Search), teer decrease (Expand Search), use decreased (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a we » a web (Expand Search), a e (Expand Search), a de (Expand Search)
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Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant
Published 2019“…Several drugs targeting the protease have been developed, but drug-resistant mutant strains emerged. Here, we screened a library and synthesized a novel class of small molecules based on a tryptophan derivative scaffold identified as HCV NS3/4A protease inhibitors that are active against both wild type and mutant form of the protease. …”
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11715
S1 Data -
Published 2024“…We analyzed SSTR in cardiac samples from patients with end-stage ischemic cardiomyopathy (ICM, n = 8) and control hearts (n = 5). …”
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11716
Differences in abundance of non-lipid molecules in liver of <i>Fmo5</i><sup><i>-/-</i></sup> and WT mice.
Published 2023“…Red dots are non-lipids that are significantly increased or decreased in <i>Fmo5</i><sup><i>-/-</i></sup> mice with a -log<sub>10</sub> <i>q</i> above 1.301 (<i>q</i> <0.05) (grey line). …”
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11717
RORγt-expressing cells attenuate cardiac remodeling after myocardial infarction
Published 2017“…Finally, the mRNA expression of RORγt, IL-17A, IL-17F and IL-23 receptor (IL-23R) mRNA and protein expression of IL-10 were decreased in RORγt<sup>+/-</sup> hearts.…”
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11718
Mouse models for hereditary spastic paraplegia uncover a role of PI4K2A in autophagic lysosome reformation
Published 2021“…We further show that PI4K2A (phosphatidylinositol 4-kinase type 2 alpha), which phosphorylates phosphatidylinositol to phosphatidylinositol-4-phosphate (PtdIns4P), accumulated in autofluorescent deposits isolated from KO but not WT brains. …”
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11720