Long non-coding RNA PMS2L2 is down-regulated in osteoarthritis and inhibits chondrocyte proliferation by up-regulating miR-34a by Fei Yang (46361)

Table_2_Causal Relationship Between Lung Function and Atrial Fibrillation: A Two Sample Univariable and Multivariable, Bidirectional Mendelian Randomization Study.XLSX by Qiaoyun Zhang (11677849)

“…The forward MR-Egger showed that each standard deviation (SD) increase in FEV1/FVC was related to a higher AF risk (OR = 1.502, 95% CI = 1.178–1.915, P = 0.006) without heterogeneity (Q_pval = 0.064), but pleiotropy effect exist (intercept = −0.017, P = 0.012). …”

Table_1_Causal Relationship Between Lung Function and Atrial Fibrillation: A Two Sample Univariable and Multivariable, Bidirectional Mendelian Randomization Study.DOCX by Qiaoyun Zhang (11677849)

“…The forward MR-Egger showed that each standard deviation (SD) increase in FEV1/FVC was related to a higher AF risk (OR = 1.502, 95% CI = 1.178–1.915, P = 0.006) without heterogeneity (Q_pval = 0.064), but pleiotropy effect exist (intercept = −0.017, P = 0.012). …”

A comparison of beta-amyloid turnover parameters in subjects with normal cognition (NC), patients with either early-onset and late-onset mild cognitive impairment (EMCI and LMCI),... by Dmitry V. Zaretsky (14034897)

Direct comparison of bacterial taxonomic abundance between BD patients and normal individuals. by Jun Shimizu (548113)

“…We found that there were significant differences in 11 bacterial taxa (also shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0153746#pone.0153746.g002" target="_blank">Fig 2</a> with asterisks). …”

Data_Sheet_1_Short-Term Changes in Mental, Physical, and Social Factors After Metabolic Bariatric Surgery in Adolescents: A Nationwide Prospective Cohort Study.DOCX by Ariela Goldenshluger (12533617)

“…Energy level increased by 24%, mood level by 14%, and mental health by 9.5% (p ≤ 0.002). Social parameters were also improved, with a significant decrease in social rejection (p = 0.02), and an increase in participation in after-school social activities (p = 0.008). …”

Vital signs of the systemic inflammatory response syndrome in adult patients with acute infections presenting in out-of-hours primary care: A cross-sectional study by Feike J. Loots (10788421)

“…</p> <p>To determine how frequently abnormalities in the vital signs of SIRS are present in adult out-of-hours (OOH) primary care patients with suspected infections and assess the association with acute hospital referral.</p> <p>We conducted a cross-sectional study at the OOH GP cooperative in Nijmegen, the Netherlands, between August and October 2015. …”

Image_5_The devil is in the details: Variable impacts of season, BMI, sampling site temperature, and presence of insects on the post-mortem microbiome.JPEG by Aaron M. Tarone (8138154)

“…</p>Results<p>We found that season, temperature at the sampling site, BMI, and sex had a significant effect on the post-mortem microbiome, the presence of insects has a homogenizing influence on the total bacterial community, and that community consistency from repeat sampling decreases as the decomposition process progresses. …”

Phospholipid Mediated Activation of Calcium Dependent Protein Kinase 1 (<em>Ca</em>CDPK1) from Chickpea: A New Paradigm of Regulation by Ajay Kumar Dixit (113592)

“…Diacylgylerol, the neutral lipid known to activate mammalian PKC, stimulated <em>Ca</em>CDPK1 but at higher concentrations. Increase in V_max of the enzyme activity by these phospholipids significantly decreased the K_m indicating that phospholipids enhance the affinity towards its substrate. …”

Image5_Transcriptomic Analysis of the Mechanisms for Alleviating Psoriatic Dermatitis Using Taodan Granules in an Imiquimod-Induced Psoriasis-like Mouse Model.tiff by Le Kuai (7825949)

“…Finally, the sequencing results were verified using a multitude of methods, and the mechanism of action of TDGs against psoriasis was found to be via the upregulation of metabolic signaling pathways such as the Gly-Ser-Thr axis, the downregulation of immune and inflammatory pathways, and the decrease in Rac2 and Arhgdib concentrations. …”

Data_Sheet_1_The combined impact of redcedar encroachment and climate change on water resources in the Nebraska Sand Hills.docx by Yaser Kishawi (12959564)

“…We, therefore, built: i) the historical scenario (2000–2019) with the current climate and redcedar cover leading to baseline results; ii) the most-likely future scenario (2020–2099) with projected climate (50^th percentile of aridity index distribution) and redcedar encroachment that was estimated by using a combination of neural network and Markov-chain cellular automata model; iii) 16 future scenarios (2020–2099) with different combinations of extreme climate (5^th and 95^th percentiles of aridity index distribution) and four hypothetical encroachment scenarios (0.5, 2.4, 4.6, and 11.9%). …”

Transient and Prolonged Response of Chicken Cecum Mucosa to Colonization with Different Gut Microbiota by Jiri Volf (126447)

“…To characterise the proteins that may directly interact with the microbiota we characterised chicken proteins that co-purified with the microbiota and identified a range of host proteins including CDD, ANGPTL6, DMBT1-L, MEP1A and Ig lambda. …”

Image1_YRDC Mediates the Resistance of Lenvatinib in Hepatocarcinoma Cells via Modulating the Translation of KRAS.TIF by Jun Guo (85069)

“…Furthermore, we found that lenvatinib inhibited the expression of YRDC in a time-dependent manner. …”

Barramundi growth data from Fish face a trade-off between ‘eating big’ for growth efficiency and ‘eating small’ to retain aerobic capacity by Tommy Norin (4425967)

“…Large meals required a greater absolute investment of energy to process (a larger so-called specific dynamic action, SDA), but the percentage of digestible meal energy required in the SDA response (SDA coefficient) decreased with increasing meal size. …”

Image_5_Adipose Tissue Myeloid-Lineage Neuroimmune Cells Express Genes Important for Neural Plasticity and Regulate Adipose Innervation.tiff by Magdalena Blaszkiewicz (7372892)

“…However, in scWAT, their functions beyond degrading norepinephrine in an obese state remain largely unexplored. We previously reported that a myeloid-lineage knockout (KO) of brain-derived neurotrophic factor (BDNF) resulted in decreased innervation of scWAT, accompanied by an inability to brown scWAT after cold stimulation, and increased adiposity after a high-fat diet. …”

Table_5_Adipose Tissue Myeloid-Lineage Neuroimmune Cells Express Genes Important for Neural Plasticity and Regulate Adipose Innervation.docx by Magdalena Blaszkiewicz (7372892)

“…However, in scWAT, their functions beyond degrading norepinephrine in an obese state remain largely unexplored. We previously reported that a myeloid-lineage knockout (KO) of brain-derived neurotrophic factor (BDNF) resulted in decreased innervation of scWAT, accompanied by an inability to brown scWAT after cold stimulation, and increased adiposity after a high-fat diet. …”

Image_2_The Gene Encoding Subunit A of the Vacuolar H+-ATPase From Cotton Plays an Important Role in Conferring Tolerance to Water Deficit.TIF by Na Liu (102929)

“…However, there are no reports on the role of V-ATPase subunit A (VHA-A) in dehydration tolerance of cotton. …”

Image_3_The Gene Encoding Subunit A of the Vacuolar H+-ATPase From Cotton Plays an Important Role in Conferring Tolerance to Water Deficit.TIF by Na Liu (102929)

“…However, there are no reports on the role of V-ATPase subunit A (VHA-A) in dehydration tolerance of cotton. …”

Image_1_The Gene Encoding Subunit A of the Vacuolar H+-ATPase From Cotton Plays an Important Role in Conferring Tolerance to Water Deficit.TIF by Na Liu (102929)

“…However, there are no reports on the role of V-ATPase subunit A (VHA-A) in dehydration tolerance of cotton. …”

Data_Sheet_1_Circulating vitamin levels mediate the causal relationship between gut microbiota and cholecystitis: a two-step bidirectional Mendelian randomization study.docx by Changhong Miao (422474)

“…Subsequently, we conducted a two-step analysis to investigate the causal effects between gut microbiota and cholecystitis. …”