The Tissue-Specific RNA Binding Protein T-STAR Controls Regional Splicing Patterns of <i>Neurexin</i> Pre-mRNAs in the Brain by Ingrid Ehrmann (191911)

“…Mice null for T-STAR developed normally and were fertile, surprisingly, given the high expression of T-STAR in the testis and the brain, and the known infertility and pleiotropic defects of Sam68 null mice. Using a transcriptome-wide search for splicing targets in the adult brain, we identified T-STAR protein as a potent splicing repressor of the alternatively spliced segment 4 (AS4) exons from each of the <i>Neurexin1-3</i> genes, and exon 23 of the <i>Stxbp5l</i> gene. …”

Image3_Small Molecule RPI-194 Stabilizes Activated Troponin to Increase the Calcium Sensitivity of Striated Muscle Contraction.pdf by Zabed Mahmud (12827819)

“…<p>Small molecule cardiac troponin activators could potentially enhance cardiac muscle contraction in the treatment of systolic heart failure. We designed a small molecule, RPI-194, to bind cardiac/slow skeletal muscle troponin (Cardiac muscle and slow skeletal muscle share a common isoform of the troponin C subunit.) …”

DataSheet1_Small Molecule RPI-194 Stabilizes Activated Troponin to Increase the Calcium Sensitivity of Striated Muscle Contraction.docx by Zabed Mahmud (12827819)

“…<p>Small molecule cardiac troponin activators could potentially enhance cardiac muscle contraction in the treatment of systolic heart failure. We designed a small molecule, RPI-194, to bind cardiac/slow skeletal muscle troponin (Cardiac muscle and slow skeletal muscle share a common isoform of the troponin C subunit.) …”

Image2_Small Molecule RPI-194 Stabilizes Activated Troponin to Increase the Calcium Sensitivity of Striated Muscle Contraction.pdf by Zabed Mahmud (12827819)

“…<p>Small molecule cardiac troponin activators could potentially enhance cardiac muscle contraction in the treatment of systolic heart failure. We designed a small molecule, RPI-194, to bind cardiac/slow skeletal muscle troponin (Cardiac muscle and slow skeletal muscle share a common isoform of the troponin C subunit.) …”

Intrastromal corneal ring segment implantation for ectasia after refractive surgery by Larissa Rossana Souza Stival (5763188)

Targeting the IL-6 Dependent Phenotype Can Identify Novel Therapies for Cholangiocarcinoma by Chiara Braconi (235041)

“…Co-administration of felodipine and gemcitabine decreased the growth of Mz-ChA-1 cell xenografts in nude athymic mice.…”

Table_3_Use of Synthetic Salmon GnRH and Domperidone (Ovaprim®) in Sharks: Preparation for ex situ Conservation.docx by Sang Wha Kim (5600183)

“…The experiment was conducted on two shark species—Triakis scyllium and Triaenodon obesus. We found that intramuscular injections of 0.2 mL/kg of Ovaprim^® for male T. scyllium and T. obesus, 0.2 mL/kg + 0.5 mL/kg at a 24 h interval for female T. scyllium, and 0.2 mL/kg + 0.2 mL/kg or 0.2 mL/kg + 0.3 mL/kg at a 24 h interval for female T. obesus were optimal dose protocols. …”

Characterization of <em>Amoeboaphelidium protococcarum</em>, an Algal Parasite New to the Cryptomycota Isolated from an Outdoor Algal Pond Used for the Production of Biofuel by Peter M. Letcher (379858)

“…We demonstrated that as the genomic DNA of parasite FD01 increases, the concentration of <i>S. dimorphus</i> cells decreases; consequently, this is a highly destructive pathogen. …”

Table_2_Use of Synthetic Salmon GnRH and Domperidone (Ovaprim®) in Sharks: Preparation for ex situ Conservation.docx by Sang Wha Kim (5600183)

“…The experiment was conducted on two shark species—Triakis scyllium and Triaenodon obesus. We found that intramuscular injections of 0.2 mL/kg of Ovaprim^® for male T. scyllium and T. obesus, 0.2 mL/kg + 0.5 mL/kg at a 24 h interval for female T. scyllium, and 0.2 mL/kg + 0.2 mL/kg or 0.2 mL/kg + 0.3 mL/kg at a 24 h interval for female T. obesus were optimal dose protocols. …”

Data_Sheet_1_Use of Synthetic Salmon GnRH and Domperidone (Ovaprim®) in Sharks: Preparation for ex situ Conservation.docx by Sang Wha Kim (5600183)

“…The experiment was conducted on two shark species—Triakis scyllium and Carcharhinus longimanus. We found that intramuscular injections of 0.2 mL/kg of Ovaprim^® for male T. scyllium and C. longimanus, 0.2 mL/kg + 0.5 mL/kg at a 24 h interval for female T. scyllium, and 0.2 mL/kg + 0.2 mL/kg or 0.2 mL/kg + 0.3 mL/kg at a 24 h interval for female C. longimanus were optimal dose protocols. …”

Table_1_Use of Synthetic Salmon GnRH and Domperidone (Ovaprim®) in Sharks: Preparation for ex situ Conservation.docx by Sang Wha Kim (5600183)

“…The experiment was conducted on two shark species—Triakis scyllium and Triaenodon obesus. We found that intramuscular injections of 0.2 mL/kg of Ovaprim^® for male T. scyllium and T. obesus, 0.2 mL/kg + 0.5 mL/kg at a 24 h interval for female T. scyllium, and 0.2 mL/kg + 0.2 mL/kg or 0.2 mL/kg + 0.3 mL/kg at a 24 h interval for female T. obesus were optimal dose protocols. …”

Effects of IMD on the LPS-induced changes in body weight, plasma testosterone levels in vivo and H₂O₂-induced change in testosterone production in vitro. by Lei Li (29537)

“…All data were expressed as mean ± SEM; * P<0.05 by one-way ANOVA followed by Student–Newmann–Keuls test for (A) and (B); * P<0.05 by Student t-test for (C); n = 5–7.…”

MnSOD protein expression in CTS and DD fibroblasts. by Carina Jaekel (11146382)

“…<p>The expression of MnSOD in blue light irradiated DD fibroblasts was significantly inhibited in comparison to irradiated CTS fibroblasts on day 3 (A). Furthermore, MnSOD expression was significantly decreased in irradiated and as well as in irradiated and TGF-β1activated DD fibroblasts on day 3 (A). …”

Water contact angle of uncoated and collagen IV coated PDMS formulations. by Rachelle N. Palchesko (113461)

“…<p>The water contact angles of all uncoated PDMS formulations (black) are approximately 110°, indicating a similar surface energy and hydrophobicity. The water contact angles of all PDMS formulations decreases to approximately 100° when coated with collagen type IV (gray), indicating similar protein adsorption behavior and surface energy. …”

Data_Sheet_1_High-Resolution Reanalysis of the Mediterranean Sea Biogeochemistry (1999–2019).pdf by Gianpiero Cossarini (108522)

“…The vertical dynamics of phytoplankton and nitrate are positively evaluated with specific metrics using BGC-Argo data. As a consequence of the continuous increases in temperature and salinity documented in the Mediterranean Sea over the last 20 years and atmospheric CO₂ invasion, we observe basin-wide biogeochemical signals indicating surface deoxygenation, increases in alkalinity, and dissolved inorganic carbon concentrations, and decreases in pH at the surface. …”

Ictogenic changes in input correlation and adaptation gains are associated with increased dynamical variability during baseline activity. by Scott Rich (9873638)

“…Normalization is relative to the value of these parameters in the “default” model (bright green, <i>U</i>_<i>e</i> Variance; bright red, <i>U</i>_<i>i</i> Variance and SLE rate). Plots are mean one SD over 25 independent 200 s simulations with <i>c</i> = .5. …”

Image_1_Relationship between thermohaline and biochemical patterns in the levantine upper and intermediate water masses, Southeastern Mediterranean Sea (2013–2021).tif by T. Ozer (13161888)

“…We suggest that a higher level of nutrients became available, supporting the observed long-term rise of the intergraded chlorophyll a (Chl.a) (0.89 mg m⁻² year⁻¹), with a maximum recorded during 2018–2019. …”

Modeling Splicing Protein Kinetics in the Cell Nucleus by José Rino (81063)

“…To model splicing inhibition, we assumed a decrease in available nucleoplasmic binding sites; accordingly, the pseudo on-rate in the nucleoplasm was decreased by a factor of approximately 30,000, = 10⁻⁴<i>s</i>⁻¹. …”

Localization of Mps3 during meiosis. by Ping Li (31981)

“…Mps3 was tagged with the HA epitope at its C-terminus and detected by an anti-HA antibody (12CA5). The level of Pgk1 serves as a loading control. …”

DataSheet_1_Therapeutic Potential of Pharmacological Targeting NLRP3 Inflammasome Complex in Cancer.pdf by Gulcin Tezcan (3337398)

“…Nigericin and a combination of LPS/Nigericin decreased the cell viability and proliferation. …”