Decreased surfactant lipids correlate with lung function in chronic obstructive pulmonary disease (COPD) by Christina W. Agudelo (8415171)

“…Wild-type C57BL/6 mice were exposed to 6 months of second-hand smoke in a full-body chamber. Surfactant lipids were decreased by 60% in subjects with COPD. …”

The gut microbiome and metabolome in kidney transplant recipients with normal and moderately decreased kidney function by Yang Lan (1750390)

Prb1 overexpression decreased APCs in ESCRT-mutant cells after nitrogen starvation. by Zulin Wu (4451572)

“…<p><b>A.</b> The accumulation of GFP-Atg8-labeled APCs in ESCRT- mutant (<i>snf7Δ</i>, <i>vps4Δ</i>) cells decreased with Prb1 overexpression. …”

DHA combined with the glycolysis inhibitor decreases cell viability and induces apoptosis in NSCLC cells. by Yan-jun Mi (264759)

Atmospheric Chlorine Wet Deposition in China: National Decreases but Localized Increases in Urban Agglomerations by Yue Xi (22336201)

Decreased cell growth of PGRN knock-out cell line as determined by the MTT assay. by Weifeng Zhang (134361)

UNC-62 RNAi decreases expression of collagen genes and increases expression of intestinal genes. by Eric L. Van Nostrand (30730)

“…For 1699 genes with intestine-enriched expression <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-McGhee1" target="_blank">[23]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Pauli1" target="_blank">[33]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Spencer1" target="_blank">[34]</a> as well as the subset of 291 genes that also decrease expression with age <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Budovskaya1" target="_blank">[10]</a>, we determined the average mean-centered fold-change from triplicate RNA-seq experiments of <i>unc-62</i> RNAi as compared to controls. …”

miR-132 Knockdown Decreases Dendritic Spine Density <i>In Vivo</i>. by Bryan W. Luikart (351588)

“…<p><b>a,</b> We assessed the effects of miR-132 knockdown on the dendrites of newborn neurons using a retroviral miR-132 sponge (miR-132sp) with four perfect miR-132 targets downstream of the U6 promoter and with EGFP downstream of the ubiquitin promoter. …”

Decreased Response to Acetylcholine during Aging of <i>Aplysia</i> Neuron R15 by Komolitdin Akhmedov (502827)

Heart failure decreases adipocyte progenitors with impaired differentiation capacity toward mature adipocytes by Oto Inoue (21373982)

“…With respect to the mechanism of impaired APC function in HF, we identified that augmented sympathetic nerve activity partially mediated the decrease in APC counts via unilateral adipose tissue denervation (ATD). …”

Novel agent DMAMCL suppresses osteosarcoma growth and decreases the stemness of osteosarcoma stem cell by Gen Ba (6440999)

Introduction of the D409V point mutation to the <i>GBA1</i> gene does not affect <i>GBA1</i> mRNA transcription or GCase protein translation. by Nicole K. Polinski (10947787)

Data Extraction Sheet: A sheet that contains the data that we extracted from the included studies. by Mohamed R. Abdelraouf (21501468)

Fig 5 - by Ke Lu (124270)

Subjects:

Profound loss of neprilysin accompanied by decreased levels of neuropeptides and increased CRP in ulcerative colitis by Zeynep Gök Sargın (4678663)

“…GEBOES grading system was also used. We demonstrated a profound loss (69.4%) of NEP expression in UC, whereas all healthy controls had NEP expression. …”

Lipolytic treatment decreased cellular neutral lipids and increased extracellular fatty acids and glycerol. by Caroline Louis (332423)

“…Cellular neutral lipids (corresponding to µmol of fatty acids in cellular neutral lipids) were expressed per mg of total cell protein (A). A significant decrease of cellular lipid contents was noted throughout the lipolytic process for the conditions with PCB-28 (<i>p</i> = 0.005) and the cocktail of PCBs (<i>p</i> = 0.029). …”

Muscle quality, but not muscle thickness, is decreased in different age groups of active older women by Pedro Lopez (4530202)

A Point Mutation in a lincRNA Upstream of <i>GDNF</i> Is Associated to a Canine Insensitivity to Pain: A Spontaneous Model for Human Sensory Neuropathies by Jocelyn Plassais (564630)

“…Clinical signs appear in young puppies and consist of acral analgesia, with or without sudden intense licking, biting and severe self-mutilation of the feet, whereas proprioception, motor abilities and spinal reflexes remain intact. Through a Genome Wide Association Study (GWAS) with 24 affected and 30 unaffected sporting dogs using the Canine HD 170K SNP array (Illumina), we identified a 1.8 Mb homozygous locus on canine chromosome 4 (adj. p-val = 2.5x10^-6). …”

Nepmucin/CD300LG expression is decreased in tumors and tumor-draining lymph nodes. by Eiji Umemoto (1637)

Desmosomal Cadherins Are Decreased in Explanted Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Patient Hearts by Alexia Vite (462320)

“…</p> <p>Methods and Results</p><p>We examined plakophilin-2, desmoglein-2, desmocollin-2, plakoglobin and β-catenin protein expression levels from seven independent ARVD/C heart samples compared to two ischemic, five dilated cardiomyopathy and one healthy heart sample as controls. …”