High glucose-containing media attenuates the degradation of internalized oAβ in mixed glia cultures. by Yung-Cheng Huang (3443450)

Subjects:

Lysosomal hydrolase activities of astrocytes and microglia in mixed glia are quantified in a cell type-specific manner. by Yung-Cheng Huang (3443450)

Subjects:

Downregulation of <i>wnt5b</i> during gastrulation by <i>lbx1b</i> overexpression. by Long Guo (548453)

“…<p>(A) <i>In situ</i> hybridization for non-canonical Wnt/PCP ligands (<i>wnt5b</i> and <i>wnt11</i>) in control and <i>lbx1b</i>-overexpressing embryos at 90% epiboly. …”

miR-10b confers anchorage-independence and increases invasive capacity of melanoma cell lines. by Ila Datar (433874)

Data_Sheet_5_Probiotic Supplementation Prevents the Development of Ventilator-Associated Pneumonia for Mechanically Ventilated ICU Patients: A Systematic Review and Network Meta-an... by Cong Li (115171)

“…The registration number of Prospero is CRD42020195773.</p>Results<p>A total of 8339 patients from 31 RCTs were finally included in network meta-analysis. …”

Table_1_Direct medical costs of ischemic heart disease in urban Southern China: a 5-year retrospective analysis of an all-payer health claims database in Guangzhou City.docx by Peixuan Xie (15428675)

Graphical example of how mean squared error (MSE) can decrease while skill gets worse for two region example. by Graham Casey Gibson (7962281)

“…Since a decrease in MSE means an improvement and a decrease in forecast skill means a lack of improvement, we see that coherence can have opposite effects on the two scores.…”

B-Raf^V600E melanoma cells acquire cancer phenotypes partly by increasing the expression levels of miR-10b. by Ila Datar (433874)

“…<p>(a) Upper panel: B-Raf^V600E knockdown decreases number of colonies in soft agar in sk-mel-28 cell line. …”

Analgesic prescriptions received by patients before commencing the BOA model of care for osteoarthritis: a Swedish national registry study with matched reference and clinical guide... by Allan Abbott (6032138)

“…Since guideline publication, the proportion of the OA cohort having no dispensed prescription analgesics prior to non-pharmacological primary care intervention concordantly increased by 5.0% (95% CI 4.2–5.9). Furthermore, dispensed prescriptions concordantly decreased for non-selective NSAIDs –8.6% (CI –9.6 to –7.6), weak opioids –6.8% (CI –7.7 to –5.9), glucosamine –9.5% (CI –9.8 to –8.8). and hyaluronic acid –1.6% (CI –1.8 to –1.5) but discordantly increased for strong opioids 2.8% (CI 2.1–3.4) and glucocorticoid intra-articular injection for hip OA 2.1% (CI 1.0–3.1).…”

Relative <i>CHRNA5</i> promoter activity in BE(2)-C cells. by Glenn A. Doyle (209929)

“…The deletion (“d” in construct name) or normal (“i” in construct name) allele at rs3841324 is indicated by a red triangle or blue square, respectively. The deletion (“d”) constructs exhibited decreased activity (1.6–2.0-fold) relative to the normal (“i”) constructs. …”

DataSheet1_Physiologically Based Pharmacokinetic Modeling in Pregnant Women Suggests Minor Decrease in Maternal Exposure to Olanzapine.docx by Liang Zheng (206933)

Plant and Animal Species Activity in a Forest Setting by Patricia Agustin (3115977)

“…All of these categories will increase/decrease in number in a particular setting. In the case of the Saywell Forest, there will be a decrease of ground cover will occur in the forest setting.…”

Even a Chronic Mild Hyperglycemia Affects Membrane Fluidity and Lipoperoxidation in Placental Mitochondria in Wistar Rats by María del Consuelo Figueroa-García (832711)

“…<div><p>It is known the deleterious effects of diabetes on embryos, but the effects of diabetes on placenta and its mitochondria are still not well known. In this work we generated a mild hyperglycemia model in female wistar rats by intraperitoneal injection of streptozotocin in 48 hours-old rats. …”

Backbone RMSD of mutant D314N throughout a 100ns MD simulation. by Bruna Baumgarten Krebs (3153162)

“…<p>To confirm that mutant D314N stayed stable with an RMSD of 0.6nm, we carried a 100ns MD simulation. The mutant seemed to stabilize at 12ns with an RMSD of 0.5nm, but an increase is noticeable at 40ns, when the backbone RMSD achieves 0.6nm. …”

Long-noncoding RNA HOXA transcript at the distal tip ameliorates the insulin resistance and hepatic gluconeogenesis in mice with gestational diabetes mellitus via the microRNA-423-... by Qianqian Cao (7309022)

“…The relations among HOTTIP, miR-423-5p and WNT7A were validated. HOTTIP and WNT7A levels were decreased while miR-423-5p was elevated in GDM mice. …”

Exendin–4 and metformin decrease the number of Ki67 and P504S-positive cells, and increase GLP-1R expression. by Yoko Tsutsumi (803696)

Reconstruction of the Evolutionary Dynamics of A(H3N2) Influenza Viruses Circulating in Italy from 2004 to 2012 by Erika Ebranati (120461)

“…<div><p>Background</p><p>Influenza A viruses are characterised by their rapid evolution, and the appearance of point mutations in the viral hemagglutinin (HA) domain causes seasonal epidemics. …”

Bone Morphogenetic Protein Type I Receptor Antagonists Decrease Growth and Induce Cell Death of Lung Cancer Cell Lines by Elaine Langenfeld (402034)

“…Lung cancer cell lines express alk2, alk3, and alk6 and inhibition of a single BMP receptor was not sufficient to decrease signaling. …”

Anti-influenza A virus activity of rhein through regulating oxidative stress, TLR4, Akt, MAPK, and NF-κB signal pathways - Fig 4 by Qian-Wen Wang (3467420)

Comparing A) ROS and B) GSH levels in COCs versus DOs recovered from PMSG-stimulated NMRI mice cultured in absence or presence of 0.5 µM PA during IVM. Data are presented as means... by Shahrzad Ronasi (20933556)