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100281
ESI–MS/MS and MALDI-IMS Localization Reveal Alterations in Phosphatidic Acid, Diacylglycerol, and DHA in Glioma Stem Cell Xenografts
Published 2015“…However, recent evidence has demonstrated the promise of bone marrow-derived mesenchymal stem cells (BM-hMSCs) as a therapeutic delivery vehicle for anti-glioma agents due to their ability to migrate or home to human gliomas. …”
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100282
Dataset for: The impact of exercise intensity on whole body and adipose tissue metabolism during energy restriction in sedentary overweight men and postmenopausal women
Published 2017“…Insulinaemic responses to a standard glucose load decreased similarly at follow-up relative to baseline in VIG (∆ 8.6 ± 15.4 nmol.120min.l-1) and MOD (∆ 5.4 ± 8.5 nmol.120min.l-1; P<0.05). …”
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100283
CPEB3-KO mice with normal mechanical sensation were more sensitive to noxious heat than WT littermate mice.
Published 2016“…For each paw, a von Frey fiber was applied 5 times at 5-s intervals. …”
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100284
Data_Sheet_1_Downregulation of let-7 by Electrical Acupuncture Increases Protein Synthesis in Mice.pdf
Published 2021“…MicroRNA-deep sequencing demonstrated that four members of the Let-7 miRNA family were significantly decreased in serum exosomes. Real time qPCR further verified Acu/LFES-mediated decreases of let-7c-5p in serum exosomes and skeletal muscles. …”
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100285
Reduced CFTR and CREB expression in human azoospermia testes.
Published 2011“…<p>(<b>A</b>) Representative immunoinfluoresence staining of CFTR (red) and Protamine-2 (green) in normal human (n = 5) and azoospermia patients (n = 6) testes, counterstained with Hoechst (blue). …”
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100286
Kinase activity in xenografts following androgen-deprivation therapy (ADT).
Published 2013“…<p>(A) Decreased (blue; negative log<sub>2</sub> ratio) and increased (red; positive log<sub>2</sub> ratio) phosphorylation levels of kinase peptide substrates by androgen-deprived (AD), long-term AD (ADL), and castration-resistant (CR) prostate carcinoma xenografts compared to ADT-naïve tumors (mean ratio and s.e.m. per substrate). …”
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100287
Pre-treatment with leptin partially retrieves the depressive action of hypoxia.
Published 2013“…Regarding 18 DIV neurons, firing frequency decreased from to 1.5±0.2 Hz to 1.0±0.2 Hz (n = 6, p<0.01) after hypoxia. …”
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100288
Ezh2 SET domain depletion caused blockade of the cellular differentiation in embryonic liver.
Published 2014“…<p>A: Western blot analysis for Albumin (hepatocyte marker) in the CD45<sup>−</sup> TER119<sup>−</sup> non-hematopoietic liver cells from control (Rosa26::CreER(T2)<sup>−/−</sup>;Ezh2<sup>F/F</sup> mouse) and Ezh2 KO (Ezh2 SET domain depleted mouse; Rosa26::CreER(T2)<sup>+/−</sup>;Ezh2<sup>F/F</sup> mouse) at ED 18.5 after 3 days TAM injection (TAM; ED 10.5–12.5). …”
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100289
Salinomycin inhibits HepG2 and Huh7 autophagic flux.
Published 2014“…<p>HepG2 and Huh7 cells were exposed to different concentrations of Salinomycin (0.5, 2 and 8 µM) for different time points and analyzed for activity of autophagy. …”
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100290
High levels of glucose alter H3K27me3 and RNA polymerase 2 association at the miR-200b promoter region.
Published 2015“…Association of Pol2 at the miR-200b promoter region was significantly decreased in HG compared to 5mM NG. <b>C:</b> ChIP-qPCR analysis of H3K27me3 at the human alpha-satelite region. …”
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100291
Cation-Poor Complex Metallic Alloys in Ba(Eu)–Au–Al(Ga) Systems: Identifying the Keys that Control Structural Arrangements and Atom Distributions at the Atomic Level
Published 2015“…Whereas <b>I</b> and <b>II</b> originate from the NaZn<sub>13</sub>-type structure (<i>cF</i>104–112, <i>Fm</i>3̅<i>c</i>), <b>III</b> (<i>tP</i>52, <i>P</i>4/<i>nbm</i>) is derived from the tetragonal Ce<sub>2</sub>Ni<sub>17</sub>Si<sub>9</sub>-type, and <b>IV</b> (<i>oP</i>104, <i>Pbcm</i>) crystallizes in a new orthorhombic structure type. Both <b>I</b> and <b>II</b> feature formally anionic networks with completely mixed site occupation by Au and triel (<i>Tr = </i> Al, Ga) atoms, while a successive decrease of local symmetry from the parental structures of <b>I</b> and <b>II</b> to <b>III</b> and, ultimately, to <b>IV</b> correlates with increasing separation of Au and Tr on individual crystallographic sites. …”
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100292
COWPEA LEAF AREA, BIOMASS PRODUCTION AND PRODUCTIVITY UNDER DIFFERENT WATER REGIMES IN CASTANHAL, PARÁ, BRAZIL
Published 2018“…Mean stomatal conductance was reduced by 73% in the grain-filling stage as a result of the lower water availability during this period. …”
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100293
Effects of ASM inhibitors on lifespan regulation and enzyme activity in <i>C. elegans</i>.
Published 2012“…<p>Lifespan assays were carried out at 20°C. (A) and (B) Wild-type (N2) animals were plated on plates containing 30 µM desipramine (A), 5 µM clomipramine (B) or vehicle control (0 µM in panel A or B). …”
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100294
Workers of the hospital maintenance sector: protection, hearing symptoms and noise exposure
Published 2018“…Noise perception in the maintenance service was medium (53%) and high (44%), evidenced noise levels of 62.0 to 101dB (A). Conclusion: the hearing protector was worn by 59.7% of the workers, the plug model was the most used (47.4%) and 75.8% reported that occupational noise decreased with the use of hearing protectors. …”
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100295
Counting of cell nuclei in SD and PKD rats after EPO-treatment.
Published 2014“…<p>Four week old heterozygous male PKD rats (n = 4) were treated three times a week with 0.5 ml/kg body weight DynEpo intraperitoneally for four weeks. …”
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100296
Table_2_PDIA2 Bridges Endoplasmic Reticulum Stress and Metabolic Reprogramming During Malignant Transformation of Chronic Colitis.docx
Published 2022“…</p>Results<p>AOM/DSS treatment induced 38 tumors in 10 mice at the 14th week with the mean tumor size 9.35 ± 3.87 mm<sup>2</sup>, which was significantly decreased to 5.85 ± 0.95 mm<sup>2</sup> by the ER stress inhibitor 4-phenylbutyric acid (4PBA). …”
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100297
Image_3_PDIA2 Bridges Endoplasmic Reticulum Stress and Metabolic Reprogramming During Malignant Transformation of Chronic Colitis.tif
Published 2022“…</p>Results<p>AOM/DSS treatment induced 38 tumors in 10 mice at the 14th week with the mean tumor size 9.35 ± 3.87 mm<sup>2</sup>, which was significantly decreased to 5.85 ± 0.95 mm<sup>2</sup> by the ER stress inhibitor 4-phenylbutyric acid (4PBA). …”
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100298
Image_4_PDIA2 Bridges Endoplasmic Reticulum Stress and Metabolic Reprogramming During Malignant Transformation of Chronic Colitis.tif
Published 2022“…</p>Results<p>AOM/DSS treatment induced 38 tumors in 10 mice at the 14th week with the mean tumor size 9.35 ± 3.87 mm<sup>2</sup>, which was significantly decreased to 5.85 ± 0.95 mm<sup>2</sup> by the ER stress inhibitor 4-phenylbutyric acid (4PBA). …”
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100299
Image_7_PDIA2 Bridges Endoplasmic Reticulum Stress and Metabolic Reprogramming During Malignant Transformation of Chronic Colitis.tif
Published 2022“…</p>Results<p>AOM/DSS treatment induced 38 tumors in 10 mice at the 14th week with the mean tumor size 9.35 ± 3.87 mm<sup>2</sup>, which was significantly decreased to 5.85 ± 0.95 mm<sup>2</sup> by the ER stress inhibitor 4-phenylbutyric acid (4PBA). …”
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100300
Table_3_PDIA2 Bridges Endoplasmic Reticulum Stress and Metabolic Reprogramming During Malignant Transformation of Chronic Colitis.docx
Published 2022“…</p>Results<p>AOM/DSS treatment induced 38 tumors in 10 mice at the 14th week with the mean tumor size 9.35 ± 3.87 mm<sup>2</sup>, which was significantly decreased to 5.85 ± 0.95 mm<sup>2</sup> by the ER stress inhibitor 4-phenylbutyric acid (4PBA). …”