Association of azithromycin with outcomes. by Martin Modrák (5101439)

“…The “Suspicious” section shows models that were found to not fit the data well or have computational issues—see supplementary statistical analysis for details. Each row represents a model—Categorical All/7/28 = Bayesian categorical regression for state at last observed day/day 7/day 28, Binary All/7/28 = Bayesian logistic regression for state at last observed day/day 7/day 28, Bayes Cox = Bayesian version of the Cox proportional hazards model with a binary outcome, Cox (single) = frequentist Cox model with a binary outcome, Cox (competing) = frequentist Cox model using competing risks (as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0245103#pone.0245103.g001" target="_blank">Fig 1a</a>), HMM A = Bayesian hidden-Markov model as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0245103#pone.0245103.g001" target="_blank">Fig 1b</a> with predictors for rate groups, HMM B = Bayesian hidden-markov model as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0245103#pone.0245103.g001" target="_blank">Fig 1b</a> with predictors for individual rates, HMM C = Bayesian hidden-Markov model as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0245103#pone.0245103.g001" target="_blank">Fig 1c</a>. …”

Association of HCQ with outcomes. by Martin Modrák (5101439)

“…The “Suspicious” section shows models that were found to not fit the data well or have computational issues—see supplementary statistical analysis for details. Each row represents a model—Categorical All/7/28 = Bayesian categorical regression for state at last observed day/day 7/day 28, Binary All/7/28 = Bayesian logistic regression for state at last observed day/day 7/day 28, Bayes Cox = Bayesian version of the Cox proportional hazards model with a binary outcome, Cox (single) = frequentist Cox model with a binary outcome, Cox (competing) = frequentist Cox model using competing risks (as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0245103#pone.0245103.g001" target="_blank">Fig 1a</a>), HMM A = Bayesian hidden-Markov model as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0245103#pone.0245103.g001" target="_blank">Fig 1b</a> with predictors for rate groups, HMM B = Bayesian hidden-markov model as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0245103#pone.0245103.g001" target="_blank">Fig 1b</a> with predictors for individual rates, HMM C = Bayesian hidden-Markov model as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0245103#pone.0245103.g001" target="_blank">Fig 1c</a>. …”

Reactivity of Iron Oxide Nanoparticle Surfaces: Understanding the Role of Crystallite Size and Morphology on Contaminant Behavior by Frances Elisa Zengotita (18981665)

“…The results of the first area of research show that carbon-mediated iron reduction increases with decreasing crystallite size after vacuum annealing, whereas an oxygen annealing + vacuum annealing step changes the extent of iron reduction caused by carbon. …”

Sensitivity analysis. by Stefano Merler (42326)

“…Spatial transmission is proportional to a power law kernel 1/(1 + d^b) where <i>d</i> is the geographical distance and <i>b</i> regulates the decrease of transmission with distance. …”

Fig 9 - by Tasneem Anwar (17636327)

“…Its production reached 400000/ml in 5 days and the decrease in its production can be seen after 20 days (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0294663#pone.0294663.g009" target="_blank">Fig 9B</a>). …”

Hypothalamic Sirt1 regulates food intake through melanocortin receptors by Işin Çakir (256194)

“…<p>. <i>(A)</i> Pharmacological inhibition of Sirt1 decreases food intake (left) and body weight gain (middle) in fasted rats, whereas activation of Sirt1 increases food intake (right) in re-fed rats. n = 8–9, per treatment, and per group. …”

Exogenous expression of variants of the small G protein, N-Ras, inhibits HIV-1 gene expression. by Raymond W. Wong (8463498)

“…(<b>B</b>) Representative gel of Gag-GFP expression detected by GFP fluorescence from reducing SDS-PAGE and representative immunoblots of ERK1/2 (phospho and total), HA-tagged N-Ras, and α-tubulin/GAPDH assayed from 30 μg of cell lysates (representative of n ≥ 3–5). (<b>C-D</b>) Graphs quantifying the level of expression of (<b>C</b>) HIV-1 Gag described in (<b>B</b>, n ≥ 3–5, mean, s.e.m.) and (<b>D</b>) HIV-1 RNAs detected by qRT-PCR as described in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1008307#ppat.1008307.g002" target="_blank">Fig 2A and 2B</a> (n ≥ 3, mean, s.e.m.). …”

Hexokinase 2 (Hxk2) is the main 2DG-phosphorylating enzyme <i>in vivo</i>. by Clotilde Laussel (13237429)

“…Values are normalized to the value of the WT / 15 min (n = 3 independent experiments ± SEM, <i>p</i>value indicated, paired <i>t</i>-test) (<b>B</b>) 2DG causes a decrease in ATP content as visualized using a FRET ATP biosensor. …”

AT101 causes caspase-independent, non-apoptotic cell death in MPNST cells. by Niroop Kaza (563598)

“…<p>AT101 treated cells demonstrate a concentration- and time-dependent decrease in viability (A, B). …”

Gene expression profiling of FP^hi, FP^lo and adenoma cells. by Yoshihisa Okuchi (3098121)

“…FP^hi cells, left 4 columns; FP^lo cells, middle 6 columns; adenoma cells, right 3 columns. We focused on a total of 13,609 genes against which probes were designed in both mouse and human microarrays. …”

Image_1_ALKBH1-8 and FTO: Potential Therapeutic Targets and Prognostic Biomarkers in Lung Adenocarcinoma Pathogenesis.TIF by Geting Wu (10915236)

“…The expression levels of ALKBH1/2/4/5/7/8 were significantly increased in LUAD tissues, while the expression levels of ALKBH3/6 and FTO were decreased. …”

Table_1_ALKBH1-8 and FTO: Potential Therapeutic Targets and Prognostic Biomarkers in Lung Adenocarcinoma Pathogenesis.docx by Geting Wu (10915236)

“…The expression levels of ALKBH1/2/4/5/7/8 were significantly increased in LUAD tissues, while the expression levels of ALKBH3/6 and FTO were decreased. …”

DataSheet_1_Changes in plant nutrient status following combined elevated [CO2] and canopy warming in winter wheat.docx by Jianqing Wang (152765)

“…In contrast, elevated [CO₂] decreased K concentrations by 11.0% and 11.5% in plant shoot and root, respectively, but had no impact on N or P concentration. …”

Table_2_ALKBH1-8 and FTO: Potential Therapeutic Targets and Prognostic Biomarkers in Lung Adenocarcinoma Pathogenesis.docx by Geting Wu (10915236)

“…The expression levels of ALKBH1/2/4/5/7/8 were significantly increased in LUAD tissues, while the expression levels of ALKBH3/6 and FTO were decreased. …”

Metabolic and neuronal origins of the intrinsic flavoprotein signal response. by Cedric R. Uytingco (3371243)

“…<p><b>(A)</b> Mean flavoprotein signal amplitude of the light phase (black) and dark phase (gray) from the GL (solid) and EPL (dash) upon treatment with 10 μM DPI. …”

Hypoxia-Inducible Factor-1α Regulates Chemotactic Migration of Pancreatic Ductal Adenocarcinoma Cells through Directly Transactivating the CX3CR1 Gene by Tiansuo Zhao (139460)

“…When hypoxia-inducible factor (HIF)-1α expression was knocked down in vitro and in vivo, the expression of CX3CR1 was significantly decreased. Chromatin immunoprecipitation assay demonstrated that HIF-1α bound to the hypoxia-response element (HRE; 5′-A/GCGTG-3′) of CX3CR1 promoter under normoxia, and this binding was significantly enhanced under hypoxia. …”

Concordant Association of Insulin Degrading Enzyme Gene (<em>IDE</em>) Variants with <em>IDE</em> mRNA, Aß, and Alzheimer's Disease by Minerva M. Carrasquillo (160022)

“…Furthermore, using data from a recent genome-wide association study of two Croatian isolated populations (n = 1,879), we identified a proxy for rs6583817 that associated significantly with decreased plasma Aβ40 levels (ß = −0.124, p = 0.011) and total measured plasma Aβ levels (b = −0.130, p = 0.009). …”

DataSheet1_Dynamic changes in soil moisture in three typical landscapes of the Heihe River Basin.docx by Qianqian Gou (9693824)

“…Accordingly, we selected three typical landscape gradients—a mountain water conservation forest belt, an artificial sand-fixing forest belt at the edge of a desert oasis, and a desert riparian forest belt in the upper, middle, and lower reaches of the Heihe River Basin, respectively. …”

<b>Predation on live and artificial insect prey shows different global latitudinal patterns</b> by Elena L. Zvereva (3343679)

“…Our goals were to explore global latitudinal patterns of predator attack rates on standardised live insect prey and to compare the patterns in predation on live insects with those on plasticine prey models. We measured predation rates in 43 forested locations distributed across five continents from 34.1°S to 69.5°N latitude. …”

Apoptosis through Bcl-2/Bax and Cleaved Caspase Up-Regulation in Melanoma Treated by Boron Neutron Capture Therapy by Fernanda Faião-Flores (392392)

“…The neutron capture reaction with a boron-10 nucleus yields high linear energy transfer (LET) particles, alpha and ⁷Li, with a range of 5 to 9 µm. …”