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102561
Data Sheet 1_Cepharanthine may inhibit the proliferation of prostate cells by blocking the EGFR/PI3K/AKT signaling pathway: comprehensive network analysis, molecular docking, and e...
Published 2025“…Celigo counting revealed a significant decrease in both cell lines after 24–96 h of CEP treatment. …”
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102562
Loss of the α2β1 integrin enhanced HPV-induced papillomatosis but limited dysplasia and preneoplastic mast cell infiltration.
Published 2011“…Over time, dermal mast cell infiltration decreased. The number of mast cells in the ear skin of HPV/WT and HPV/KO animals was similar at 9 months and at sacrifice (9 months p = 0.32 , n = 5 for both groups; time of sacrifice p = 0.23, n = 5 for both groups). …”
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102563
Deletion of CDKAL1 Affects High-Fat Diet–Induced Fat Accumulation and Glucose-Stimulated Insulin Secretion in Mice, Indicating Relevance to Diabetes
Published 2012“…In accordance with the findings in mice, a nominally significant (<em>P</em><0.05) association between <em>CDKAL1</em> rs4712523 and BMI was replicated in 2 Japanese general populations comprising 5,695 and 12,569 samples; the risk allele for type 2 diabetes was also associated with decreased BMI.…”
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102564
Data_Sheet_1_Methacholine-Induced Cough in the Absence of Asthma: Insights From Impulse Oscillometry.pdf
Published 2020“…Increased peripheral airway resistance and decreased resonant frequency are associated with a decreased DI Index. …”
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102565
Data Sheet 2_Biomarker discovery for non-invasive diagnosis of inflammatory bowel disease using blood transcriptomics.xlsx
Published 2025“…LASSO and SVM identified a three-mRNA panel—IL4R, EIF5A, and SLC9A8—which achieved 84% diagnostic accuracy in the discovery cohort and 99% accuracy in the real-life cohort. …”
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102566
Data Sheet 1_Biomarker discovery for non-invasive diagnosis of inflammatory bowel disease using blood transcriptomics.docx
Published 2025“…LASSO and SVM identified a three-mRNA panel—IL4R, EIF5A, and SLC9A8—which achieved 84% diagnostic accuracy in the discovery cohort and 99% accuracy in the real-life cohort. …”
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102567
Anesthetic Sevoflurane Causes Rho-Dependent Filopodial Shortening in Mouse Neurons
Published 2016“…Yet cluster-type filopodia (a precursor to synaptic filopodia) were persistently significantly decreased in number on day-in-vitro 9, in part owing to preferential localization of drebrin immunoreactivity to dendritic shafts versus filopodial stalks. …”
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102568
Impact of Anti-Retroviral Treatment and Cotrimoxazole Prophylaxis on Helminth Infections in HIV-Infected Patients in Lambaréné, Gabon
Published 2015“…</p><p>Conclusions/Significance</p><p>CTX-P use was associated with a decreased risk of <i>Loa loa</i> infection, suggesting an anthelminthic effect of antifolate drugs. …”
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102569
Plasma miR-601 and miR-760 Are Novel Biomarkers for the Early Detection of Colorectal Cancer
Published 2012“…</p> <h3>Methodology/Principal Findings</h3><p>According to the results of miRNA profiling performed on pooling plasma samples form 10 CRC patients or 10 healthy controls, a panel of miRNAs (hsa-miR-10a, -19a, -22*, -24, -92a, 125a-5p, -141, -150, -188-3p, -192, -210, -221, -224*, -376a, -425*, -495, -572, -601, -720, -760 and hsa-let-7a, -7e) were deregulated in CRC plasma with fold changes >5. …”
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102570
Probability of microbe-free hosts in the stationary distribution.
Published 2020“…Other parameters: <i>N</i> = 10<sup>4</sup>. We use <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008392#pcbi.1008392.e017" target="_blank">Eq (5a)</a> where no definition of <i>p</i><sub><i>i</i></sub> and <i>α</i><sub><i>i</i></sub> is required.…”
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102571
Nutrition Report Cards: An Opportunity to Improve School Lunch Selection
Published 2013“…Despite the small sample, the NRC was associated with reduced selection of some items, such as the percentage of those selecting cookies which decreased from 14.3 to 6.5 percent. Additionally, despite requiring new keys on the check-out registers to generate the NRC, checkout times increased by only 0.16 seconds per transaction, and compiling and sending the NRCs required a total weekly investment of 30 minutes of staff time.…”
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102572
Supplementary Material for: An Analysis of the Association between Epilepsy-Related Genes and Vertigo in the Polish Population
Published 2018“…In contrast, the haplotype rs1939012:T-rs1783901:A showed a significant association with a decreased risk of the disease (OR = 0.0597, 95% CI = 0.0136–0.2620, <i>p</i> = 0.0002). …”
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102573
Gadolinium-free Magnetic Resonance Imaging of the Liver via an Oatp1-Targeted Manganese(III) Porphyrin
Published 2022“…Controversy surrounding gadolinium-based contrast agents (GBCAs) has rendered their continued utility highly contentious, but the liver-specific GBCA Gd(III) ethoxybenzyl-diethylene triamine pentaacetic acid (Gd(III)-EOB-DTPA) remains in use because it provides unique diagnostic information that could not be obtained by any other means. To address the need for an alternate liver-specific MRI probe, we synthesized Mn(III) 20-(4-ethoxyphenyl) porphyrin-5,10,15-tricarboxylate (Mn(III)TriCP-PhOEt), which exhibited significantly higher <i>r</i><sub>1</sub> relaxivity than Gd(III)-EOB-DTPA in vitro, while also targeting hepatocyte-specific organic anion-transporting polypeptide 1 (Oatp1) channels as a marker of viability. …”
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102574
Image_1_Prognostic Value of Right Ventricular Ejection Fraction Assessed by 3D Echocardiography in COVID-19 Patients.TIF
Published 2021“…</p><p>Results: Compared with controls, 2D-RVFWLS and 3D-RVEF were both significantly decreased in COVID-19 patients (−27.2 ± 4.4% vs. −22.9 ± 4.8%, P < 0.001; 53.7 ± 4.5% vs. 48.5 ± 5.8%, P < 0.001). …”
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102575
Presentation_1_Prognostic Value of Right Ventricular Ejection Fraction Assessed by 3D Echocardiography in COVID-19 Patients.pdf
Published 2021“…</p><p>Results: Compared with controls, 2D-RVFWLS and 3D-RVEF were both significantly decreased in COVID-19 patients (−27.2 ± 4.4% vs. −22.9 ± 4.8%, P < 0.001; 53.7 ± 4.5% vs. 48.5 ± 5.8%, P < 0.001). …”
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102576
Table1_UK midwives delivering physical activity advice; what are the challenges and possible solutions?.docx
Published 2024“…Background<p>Despite physical activity (PA) providing specific health benefits during pregnancy and the postpartum period, many women report decreased PA during this time. Provision of PA advice has been found to be lacking amongst midwives due to a range of barriers. …”
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102577
DataSheet_1_The immunosuppressive effects and mechanisms of loureirin B on collagen-induced arthritis in rats.pdf
Published 2023“…The results of qPCR showed that Kv1.3 mRNA in the PBMCs of CIA rats was significantly higher than that of the control and significantly decreased in the LrB treatment groups. In addition, we confirmed in cell models that LrB significantly decreased Kv1.3 protein on the cell membrane and inhibited the activation of Nuclear Factor of Activated T Cells 1 (NFAT1) with immune stimulus.…”
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102578
Table_2_Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection.xlsx
Published 2019“…These data may implicate IRF-8 as a novel transcription factor in the neuropathophysiology of brain abnormalities in treated HIV and serve as a potential therapeutic target to decrease the burden of cognitive dysfunction in this population.…”
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102579
Table_3_Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection.xlsx
Published 2019“…These data may implicate IRF-8 as a novel transcription factor in the neuropathophysiology of brain abnormalities in treated HIV and serve as a potential therapeutic target to decrease the burden of cognitive dysfunction in this population.…”
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102580
Table_1_Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection.xlsx
Published 2019“…These data may implicate IRF-8 as a novel transcription factor in the neuropathophysiology of brain abnormalities in treated HIV and serve as a potential therapeutic target to decrease the burden of cognitive dysfunction in this population.…”