Malaria infection enhances IL-27 expression through IFN-γ production to promote the expansion, differentiation, and mobilization of LSK cells. by Jun-ichi Furusawa (554613)

“…<i>IFN-γ</i>-deficient mice were hydrodynamically injected with IL-27-expression vector or control vector at days 0 and 4 after infection; at day 7, parasitemia was measured (E), LSK population was analyzed by flow cytometry (F), and cell numbers of LSK cells and neutrophils were counted (G). Data are shown as mean ± SEM (n = 3–5) and are representative of at least two independent experiments. …”

Table1.DOCX by Holly Stolterfoht (4862653)

“…Supported by molecular modeling, we interpreted that five of these residues are essential for catalytic activity, or substrate and co-substrate binding. …”

Substantial increase in antibody expression yields following AbLIFT design. by Shira Warszawski (7305761)

“…The inhibitory activity was measured for each antibody in a sulfhydryl oxidase assay using a physiological concentration of QSOX1 (25 nM). h492.1^des18 showed comparable inhibitory activity relative to the parental antibody, with only a slight decrease when provided at sub-stoichiometric amounts (10 nM). …”

SOCIALIZATION PROCESS IN THE IDENTITY DEVELOPMENT OF THE MEDICINE STUDENT by Clarisse Daminelli Borges Machado (6676949)

“…Through content analysis, the data analysis evidenced a growing presence, throughout the course, of what we call 'financial return,' and, inversely, a decreasing interest in 'helping others.' …”

Electrophysiological characterisation of α-MHCcells by Michael Xavier Doss (30403)

“…Statistical analysis of the effects of carbachol (1 μmol/l) and isoproterenol (1 μmol/l) on the spontaneous AP frequency. Carbachol caused a decrease whereas isoproterenol increased the spontaneous AP frequency.…”

Quantitative proteomics analysis. by Laura Piel (12251419)

“…<p>(A) Box plots representing the median ratio and the upper and lower quartiles of the LFQ intensity values for all LP biological replicates (LP.2, LP.3, LP.4 and LP.5) compared to the median of all EP replicates (EP.2, EP.3, EP.4 and EP.5). …”

Table_1_Mental Health Status of Late-Middle-Aged Adults in China During the Coronavirus Disease 2019 Pandemic.DOCX by Yong-Bo Zheng (9532996)

“…The prevalence of depression, anxiety, insomnia, and acute stress symptoms among late-middle-aged adults in China during the COVID-19 pandemic was 20.4, 27.1, 27.5, and 21.2%, respectively. Multivariable logistic regression analyses showed that participants who were quarantined had increased odds ratios for the four mental health symptoms, and those with a good understanding of the COVID-19 pandemic displayed a decreased risk for all mental health symptoms among late-middle-aged adults. …”

Data_Sheet_1_Case Report: Event-Related Desynchronization Observed During Volitional Swallow by Electroencephalography Recordings in ALS Patients With Dysphagia.pdf by Akari Ogawa (12093176)

“…It is caused by degeneration of both the bulbar motor neurons and cortical motoneurons projecting to the oropharyngeal areas. A previous report showed decreased event-related desynchronization (ERD) in the medial sensorimotor areas in ALS dysphagic patients. …”

Image_2_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.JPEG by Bradley S. Hollidge (14113539)

“…<p>Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases. Here, we characterize and compare the temporal profile of transgene expression after bilateral injections into the mouse striatum of rAAV9 encoding GFP under the control of either a ubiquitous promoter (CAG), or the neuron-specific human synapsin (hSyn) and CamKII promoters. …”

Image_4_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.JPEG by Bradley S. Hollidge (14113539)

“…<p>Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases. Here, we characterize and compare the temporal profile of transgene expression after bilateral injections into the mouse striatum of rAAV9 encoding GFP under the control of either a ubiquitous promoter (CAG), or the neuron-specific human synapsin (hSyn) and CamKII promoters. …”

Differing Causes of Lactic Acidosis and Deep Breathing in Cerebral Malaria and Severe Malarial Anemia May Explain Differences in Acidosis-Related Mortality by Nathan R. Brand (3185376)

“…In contrast, in SMA, LA was associated with a decreased hemoglobin level, but was not associated with PfHRP2 concentration or platelet count. …”

Table_1_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.pdf by Bradley S. Hollidge (14113539)

“…<p>Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases. Here, we characterize and compare the temporal profile of transgene expression after bilateral injections into the mouse striatum of rAAV9 encoding GFP under the control of either a ubiquitous promoter (CAG), or the neuron-specific human synapsin (hSyn) and CamKII promoters. …”

Image_3_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.JPEG by Bradley S. Hollidge (14113539)

“…<p>Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases. Here, we characterize and compare the temporal profile of transgene expression after bilateral injections into the mouse striatum of rAAV9 encoding GFP under the control of either a ubiquitous promoter (CAG), or the neuron-specific human synapsin (hSyn) and CamKII promoters. …”

Image_1_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.JPEG by Bradley S. Hollidge (14113539)

“…<p>Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases. Here, we characterize and compare the temporal profile of transgene expression after bilateral injections into the mouse striatum of rAAV9 encoding GFP under the control of either a ubiquitous promoter (CAG), or the neuron-specific human synapsin (hSyn) and CamKII promoters. …”

Canuel et al. - An empirical financial analysis of integrating biomass procurement in sawtimber and pulpwood harvesting in eastern Canada by Claudie-Maude Canuel (10262372)

“…We studied forest harvest operations for biomass in the form of trees and tree sections, along with sawtimber and pulpwood by evaluating the cost effectiveness of the supply chain with a particular focus on harvest costs, and potential silvicultural savings from decreasing needs in site preparation and reforestation. …”

Divergence in root functional trait variation for yield improvement by Du (17111761)

“…However, there are few studies integrating the effects of physiological and anatomical traits relevant to carbon allocation and water transport in roots on yield.We performed a global scale data analysis to quantify the ecological effects of root functional traits on yield under abiotic stress. …”

The Roles of Parathyroid Hormone-Like Hormone during Mouse Preimplantation Embryonic Development by Lei Guo (36221)

“…<div><p>Parathyroid hormone-like hormone (PTHLH) was first identified as a parathyroid hormone (PTH)-like factor responsible for humoral hypercalcemia in malignancies in the 1980s. …”

Effects of isometric handgrip training in patients with cardiovascular disease: rationale and design of the ISOPRESS network by Breno Q. Farah (840797)

“…However, several gaps in the literature still need to be addressed. Thus, we designed the ISOPRESS network group, which consists of a task force of different research groups aimed at analyzing the effects of isometric handgrip training on different contexts, parameters, and populations. …”

MicroRNA-9 restrains the sharp increase and boost apoptosis of human acute myeloid leukemia cells by adjusting the Hippo/YAP signaling pathway by Guoqing Wang (128352)

“…This study focuses on the effects of miR-9 on the regulation of AML cells and their related signaling pathways. We found that the expression of miR-9 was significantly decreased in four AML cell lines (THP-1, HL-60, TF-1 and KG-1) compared with the human normal bone marrow cells (HS-5). …”

Supplementary Material for: Clinicopathological Characteristics, Surgery and Survival Outcomes of Patients with Duodenal Gastrointestinal Stromal Tumors by Sugase T. (2871863)

“…<i>Background:</i> Duodenal gastrointestinal stromal tumors (GISTs) are a rare subset of GISTs (3-5%), and their clinicopathological features have not been fully described. …”