Image_4_Elucidating the changes in the heterogeneity and function of radiation-induced cardiac macrophages using single-cell RNA sequencing.tif by Chunxiang Cao (451327)

“…Then, we identified 7 clusters of macrophages by single-cell RNA sequencing and found two kinds of stage specific macrophages: senescence-associated macrophage (Cdkn1a^highC5ar1^high) on Day 7 and interferon-associated macrophage (Ccr2^highIsg15^high) on Day 35. …”

Image_7_Elucidating the changes in the heterogeneity and function of radiation-induced cardiac macrophages using single-cell RNA sequencing.jpeg by Chunxiang Cao (451327)

“…Then, we identified 7 clusters of macrophages by single-cell RNA sequencing and found two kinds of stage specific macrophages: senescence-associated macrophage (Cdkn1a^highC5ar1^high) on Day 7 and interferon-associated macrophage (Ccr2^highIsg15^high) on Day 35. …”

Image_1_Inositol hexakisphosphate kinases differentially regulate trafficking of vesicular glutamate transporters 1 and 2.JPEG by Haiyan Li (168109)

“…VGLUT1-pH recycles by classical AP-2 dependent endocytosis under moderate stimulation conditions, while VGLUT2-pH recycles using AP-1 and AP-3 adaptor proteins as well. Using a short stimulus to release the readily releasable pool (RRP), we show that IP6K1 KO increases exocytosis of both VGLUT1-and VGLUT2-pH, while IP6K3 KO decreases the amount of both transporters in the RRP. …”

Image_6_Elucidating the changes in the heterogeneity and function of radiation-induced cardiac macrophages using single-cell RNA sequencing.jpeg by Chunxiang Cao (451327)

“…Then, we identified 7 clusters of macrophages by single-cell RNA sequencing and found two kinds of stage specific macrophages: senescence-associated macrophage (Cdkn1a^highC5ar1^high) on Day 7 and interferon-associated macrophage (Ccr2^highIsg15^high) on Day 35. …”

Table_2_Elucidating the changes in the heterogeneity and function of radiation-induced cardiac macrophages using single-cell RNA sequencing.xlsx by Chunxiang Cao (451327)

“…Then, we identified 7 clusters of macrophages by single-cell RNA sequencing and found two kinds of stage specific macrophages: senescence-associated macrophage (Cdkn1a^highC5ar1^high) on Day 7 and interferon-associated macrophage (Ccr2^highIsg15^high) on Day 35. …”

Image_2_Inositol hexakisphosphate kinases differentially regulate trafficking of vesicular glutamate transporters 1 and 2.JPEG by Haiyan Li (168109)

“…VGLUT1-pH recycles by classical AP-2 dependent endocytosis under moderate stimulation conditions, while VGLUT2-pH recycles using AP-1 and AP-3 adaptor proteins as well. Using a short stimulus to release the readily releasable pool (RRP), we show that IP6K1 KO increases exocytosis of both VGLUT1-and VGLUT2-pH, while IP6K3 KO decreases the amount of both transporters in the RRP. …”

Expression of Kruppel-Like Factor KLF4 in Mouse Hair Follicle Stem Cells Contributes to Cutaneous Wound Healing by Juan Li (146180)

“…Consistently, KLF4 knockdown by KLF4-specific small hairpin RNA in human A431 epidermoid carcinoma cells decreased the stem cell population and was accompanied by compromised cell migration.…”

Image_3_Elucidating the changes in the heterogeneity and function of radiation-induced cardiac macrophages using single-cell RNA sequencing.tif by Chunxiang Cao (451327)

“…Then, we identified 7 clusters of macrophages by single-cell RNA sequencing and found two kinds of stage specific macrophages: senescence-associated macrophage (Cdkn1a^highC5ar1^high) on Day 7 and interferon-associated macrophage (Ccr2^highIsg15^high) on Day 35. …”

Amphetamine-Induced Displacement of [¹¹C]FLB 457 Binding Potential. by Rajesh Narendran (304516)

“…<p>The bar graph shows [¹¹C]FLB 457 BP_ND under baseline (white bars) and post-amphetamine (black bars) conditions in n = 31 healthy subjects. Amphetamine led to a significant decrease in five of the eight cortical regions of interest (* denotes p < 0.05, paired t-tests) consistent with previous reports [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0157867#pone.0157867.ref009" target="_blank">9</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0157867#pone.0157867.ref011" target="_blank">11</a>].…”

Table1_Origins of sediments and fluids in submarine mud volcanoes off Tanegashima Island, northern Ryukyu Trench, Japan.xlsx by Akira Ijiri (5118521)

“…We estimated the ages of the source sequences of the mud volcano sediments to be middle to late Miocene based on nannofossils and ¹⁰Be ages. …”

Possible Involvement of Locus-Specific Methylation on Expression Regulation of <i>LEAFY</i> Homologous Gene (<i>CiLFY</i>) during Precocious Trifoliate Orange Phase Change Process by Jin-Zhi Zhang (139230)

“…Raf) was treated with 5-azacytidine and displayed a number of phenotypic and developmental abnormalities. …”

Identification of Pax6-Dependent Gene Regulatory Networks in the Mouse Lens by Louise V. Wolf (268629)

“…Of these, 178 (31.8%) were similarly increased and decreased in Pax6 homozygous embryonic telencephalon [Holm PC, Mader MT, Haubst N, Wizenmann A, Sigvardsson M, Götz M (2007) Loss- and gain-of-function analyses reveals targets of Pax6 in the developing mouse telencephalon. …”

Table_1_Influence of Combined Transcranial Direct Current Stimulation and Motor Training on Corticospinal Excitability in Children With Unilateral Cerebral Palsy.DOCX by Samuel T. Nemanich (6630293)

“…Contralesional MEP amplitude decreased as hypothesized in five of five participants receiving active tDCS immediately after and 6 months after the intervention, however no statistically significant differences between intervention groups were noted for MEP amplitude [mean difference = −323.9 μV, 95% CI = (−989, 341), p = 0.34] or CSP duration [mean difference = 3.9 ms, 95% CI = (−7.7, 15.5), p = 0.51]. …”

Data_Sheet_1_Pulmonary Valve Replacement in Repaired Tetralogy of Fallot: Midterm Impact on Biventricular Response and Adverse Clinical Outcomes.doc by Fengpu He (12509299)

“…RV end-diastolic volume index (RVEDVI) and end-systolic volume index (RVESVI) significantly reduced early after PVR and further decreased by midterm follow-up (pre-PVR vs. early post-PVR vs. midterm post-PVR: RVEDVI, 155.2 ± 34.7 vs. 103.8 ± 31.2 vs. 95.1 ± 28.6 ml/m², p < 0.001; RVESVI, 102.9 ± 28.5 vs. 65.4 ± 28.2 vs. 57.7 ± 23.4 ml/m², p < 0.001). …”

Table_2_Influence of Combined Transcranial Direct Current Stimulation and Motor Training on Corticospinal Excitability in Children With Unilateral Cerebral Palsy.DOCX by Samuel T. Nemanich (6630293)

“…Contralesional MEP amplitude decreased as hypothesized in five of five participants receiving active tDCS immediately after and 6 months after the intervention, however no statistically significant differences between intervention groups were noted for MEP amplitude [mean difference = −323.9 μV, 95% CI = (−989, 341), p = 0.34] or CSP duration [mean difference = 3.9 ms, 95% CI = (−7.7, 15.5), p = 0.51]. …”

Data_Sheet_1_Fungal Microbiota Dysbiosis and Ecological Alterations in Gastric Cancer.docx by Ping Yang (56755)

“…The presence of GC was associated with a distinct gastric fungal mycobiome signature, characterized by a decreased biodiversity and richness and significant differences in fungal composition. …”

Insulin Signaling, Lifespan and Stress Resistance Are Modulated by Metabotropic GABA Receptors on Insulin Producing Cells in the Brain of <em>Drosophila</em> by Lina E. Enell (233911)

“…<div><p>Insulin-like peptides (ILPs) regulate growth, reproduction, metabolic homeostasis, life span and stress resistance in worms, flies and mammals. A set of insulin producing cells (IPCs) in the <em>Drosophila</em> brain that express three ILPs (DILP2, 3 and 5) have been the main focus of interest in hormonal DILP signaling. …”

Reference and current Trophic Level Index of New Zealand lakes: benchmarks to inform lake management and assessment by Jonathan M. Abell (7110209)

“…Mean chl <i>a</i> increased 3.5-fold (2.42 mg m⁻³ vs. 8.32 mg m⁻³) and mean Secchi depth decreased (indicating lower clarity) by approximately one-third (9.62 m vs. 6.48 m) between reference and current states. …”

Oscillation frequency depends on stimulus contrast. by Laurence Aitchison (3594596)

“…<p><b>A.</b> The membrane potential response of one neuron to stimulus onset across 4 trials (coloured curves) shows that the variability decreases and the frequency increases as stimulus contrast increases. …”

The effect of stimulus luminance on pupil dilation. by Elena Geangu (339260)

“…<p>We explored whether variations in stimulus luminance across video frames have a significant effect on the recorded changes in pupil size. …”