Image5_PKA inhibition is a central step in D,L-methadone-induced ER Ca2+ release and subsequent apoptosis in acute lymphoblastic leukemia.JPEG by Hamza Kamran (18433152)

“…Previously, we demonstrated that D,L-methadone causes ALL cell apoptosis via μ-opioid receptor 1 (OPRM1)-triggered ER Ca²⁺ release and decrease in Ca²⁺ efflux, elevating [Ca²⁺]_i. …”

Eliminations of dorsal projections in DOM and DOM-A downregulation were due to reduced number of sLNvs and decrease of PDF. by Zhenxing Liu (399809)

Fig 5 - by Charlotte Hennah (11868929)

Fig 3 - by Min Sub Sim (8193564)

Decreased clearance of IgAN patient IgA by CD89-expressing Kupffer cells. by Lijun Xu (195394)

“…(B) sCD89-IgA complexes in cell supernatant of (A) were detected by ELISA using A3 and anti-mouse IgA mAb, using 1 μg/mL human IgA binding to 5 μg/mL recCD89 as an internal control. …”

vFLIP and vCyclin decrease SMAD2 protein expression and desensitize TGF-β signaling. by Hong Seok Choi (121525)

“…<p>(A) SMAD2 expression was drastically decreased upon the expression of vFLIP or vCyclin in SLK cells. …”

DDX3 levels are not decreased in MCMV-infected cells. by Olha Puhach (9500132)

Table_5_Transcriptional Response of Streptomyces coelicolor to Rapid Chromosome Relaxation or Long-Term Supercoiling Imbalance.pdf by Marcin Jan Szafran (6944060)

“…Using a S. coelicolor strain in which topA transcription is under the control of an inducible promoter, we identified genes involved in the transcriptional response to long-term supercoiling imbalance. …”

Dramatic Lockdown Fossil Fuel CO₂ Decrease Detected by Citizen Science-Supported Atmospheric Radiocarbon Observations by Jocelyn C. Turnbull (6083705)

“…This is consistent with sparse local traffic count information and a much larger decrease in traffic emissions than reported in global aggregate estimates of emission changes. …”

Different effects of intervention: We simulate an intervention that decreases the nosocomial transmission rate by a factor of 70% (<i>β</i>→0.3<i>β</i>) starting from January 2011. by Tal T. Robin (17847380)

Image_5_LaeA Controls Virulence and Secondary Metabolism in Apple Canker Pathogen Valsa mali.TIF by Yaqiong Feng (9604034)

“…In this study, we focus on LaeA, a known regulator of secondary metabolism, for its role in SMBGC regulation, toxin production, and virulence of V. mali. …”

Decrease of Population Divergence in Eurasian Perch (<i>Perca fluviatilis</i>) in Browning Waters: Role of Fatty Acids and Foraging Efficiency by Kristin Scharnweber (2742514)

“…We expected a decrease in the prevalence of PUFAs, which are important for perch growth and divergence with increasing DOC concentrations, due to the restructuring effects of DOC on aquatic food webs. …”

GluN2A(D731N) decreases channel open probability. by Kai Gao (120150)

“…The receptors were activated by EC₅₀ concentrations of glutamate with saturating concentration (100 μM) of glycine at holding potential of -40 mV. The di-heteromeric mutant (2A-D731N) and tri-heteromeric receptors with two-copies of the mutant subunit (D731N/D731N) showed a prolonged inhibition rate, reflecting a decreased channel open probability. …”

APB5, but not APA5, decreases apoptosis in alveolar epithelial cells in lungs of BLM-treated mice. by Masami Kishi (6167105)

“…The administration of APA5 did not change the number of TUNEL-positive cells from that in BLM-treated mice, whereas that of APB5 significantly decreased them. …”

HC-070 decreases anxiety after CCK-4 treatment in an EPM. by Stefan Just (4811358)

Multicenter Phase 2 Trial of Sirolimus for Tuberous Sclerosis: Kidney Angiomyolipomas and Other Tumors Regress and VEGF- D Levels Decrease by Sandra L. Dabora (206838)

“…Kidney angiomyolipomas regrew when sirolimus was discontinued but responses tended to persist if treatment was continued after week 52. We observed regression of brain tumors (SEGAs) in 7/11 cases (26% mean decrease in diameter), regression of liver angiomyolipomas in 4/5 cases (32.1% mean decrease in longest diameter), subjective improvement in facial angiofibromas in 57%, and stable lung function in women with TSC/LAM (n = 15). …”

Comparison among conventional high voltage step-up ratio converters with the suggested converter. by M. Zakir Hossain (6033752)

Subjects:

Proposed Full-bridge resonant cascaded (FBRC) step-up dc-dc converter. by M. Zakir Hossain (6033752)

Subjects:

<i>Cdkl5</i> -/Y mice show an increased freezing time and a decreased distance traveled during the pretone period in the altered context. by Kosuke Okuda (5150393)

“…<i>Cdkl5</i> -/Y mice show a significantly decreased distance traveled in response to the first footshock (p = 0.0158) compared with control mice. …”

a-c: Proximal tibia (PT) EPO receptor (EPO-R) decreases in uremic rats, as shown by Western blot (Fig. 5a) and immunohistochemistry (Fig. 5b). by Daniel Landau (440830)

“…Animals received a single bolus of IV rhEPO (25 U/kg) or saline, 5 minutes prior to sacrifice. …”