DataSheet1_The Role of Genetic Polymorphisms in High-Dose Methotrexate Toxicity and Response in Hematological Malignancies: A Systematic Review and Meta-Analysis.pdf by Zaiwei Song (11590222)

“…Two SNPs were statistically associated with the increased risk of HDMTX toxicity: MTHFR 677C>T and hepatotoxicity (dominant, OR=1.52, 95% CI=1.03-2.23; recessive, OR=1.68, 95% CI=1.10–2.55; allelic, OR=1.41, 95% CI=1.01–1.97), mucositis (dominant, OR=2.11, 95% CI=1.31–3.41; allelic, OR=1.91, 95% CI=1.28–2.85), and renal toxicity (recessive, OR=3.54, 95% CI=1.81–6.90; allelic, OR=1.89, 95% CI=1.18–3.02); ABCB1 3435C>T and hepatotoxicity (dominant, OR=3.80, 95% CI=1.68-8.61), whereas a tendency toward the decreased risk of HDMTX toxicity was present in three SNPs: TYMS 2R>3R and mucositis (dominant, OR=0.66, 95% CI=0.47–0.94); RFC1 80A>G and hepatotoxicity (recessive, OR=0.35, 95% CI=0.16–0.76); and MTHFR 1298A>C and renal toxicity (allelic, OR=0.41, 95% CI=0.18–0.97). …”

DataSheet1_The Role of Genetic Polymorphisms in High-Dose Methotrexate Toxicity and Response in Hematological Malignancies: A Systematic Review and Meta-Analysis.pdf by Zaiwei Song (11590222)

“…Two SNPs were statistically associated with the increased risk of HDMTX toxicity: MTHFR 677C>T and hepatotoxicity (dominant, OR=1.52, 95% CI=1.03-2.23; recessive, OR=1.68, 95% CI=1.10–2.55; allelic, OR=1.41, 95% CI=1.01–1.97), mucositis (dominant, OR=2.11, 95% CI=1.31–3.41; allelic, OR=1.91, 95% CI=1.28–2.85), and renal toxicity (recessive, OR=3.54, 95% CI=1.81–6.90; allelic, OR=1.89, 95% CI=1.18–3.02); ABCB1 3435C>T and hepatotoxicity (dominant, OR=3.80, 95% CI=1.68-8.61), whereas a tendency toward the decreased risk of HDMTX toxicity was present in three SNPs: TYMS 2R>3R and mucositis (dominant, OR=0.66, 95% CI=0.47–0.94); RFC1 80A>G and hepatotoxicity (recessive, OR=0.35, 95% CI=0.16–0.76); and MTHFR 1298A>C and renal toxicity (allelic, OR=0.41, 95% CI=0.18–0.97). …”

Incidence rate per 100 person-years of the first occurrence of OIs and death in the first two years of ART, overall and by calendar time period of ART start. by Johanna Beulah Sornillo (16985550)

Shikonin promotes ferroptosis though NSUN2-mediated m⁵C methylation modification of TFRC in acute myelocytic leukemia by Shuyu Chen (4579207)

“…<p>Shikonin (SHK), extracted from the traditional Chinese herb <i>Lithospermum erythrorhizon</i>, demonstrates a wide range of pharmacological activities. This study aimed to explore the role and underlying mechanisms of the 5-methylcytosine (m⁵C) RNA methyltransferase NOL1/NOP2/SUN domain (NSUN)2 in acute myelocytic leukemia (AML). …”

Proportion of children and adolescents on ART who used specific drug or drug combination by calendar period of initiation and drug class (n = 2019). by Johanna Beulah Sornillo (16985550)

Mycelial structures (m) of fungi are mutually surrounding root hairs (rh) of tomato showing development of „interface”for the mutual flow of water and nutrients through the fungal... by Robert Pokluda (8871407)

Variation of the number of secondary infections per 10,000 students according to the size of bubble groups. by Sergio Alonso (270169)

Physiological regions considering ventricular depth variations. by Inmaculada Villanueva-Baxarias (21454246)

Image_5_Antisense Oligonucleotide-Mediated Reduction of HDAC6 Does Not Reduce Tau Pathology in P301S Tau Transgenic Mice.jpg by Antonio Valencia (11034303)

“…Despite a robust decrease in levels of HDAC6, no increase in tau acetylation was observed. …”

Table_1_Health insurance provider and endovascular treatment availability are associated with different hemodialysis vascular access profiles: A Brazilian national survey.docx by Ricardo Portiolli Franco (5716727)

“…We conducted a cross-sectional electronic survey across 834 centers. …”

¹⁴CO₂ from L-[1-¹⁴C]Met and L-[1-¹⁴C]Cys in piglets receiving total enteral nutrition with graded levels of dietary Cys and 0.25 g kg<su... by Anna K. Shoveller (6208457)

Table_1_Feeding Pre-weaned Calves With Waste Milk Containing Antibiotic Residues Is Related to a Higher Incidence of Diarrhea and Alterations in the Fecal Microbiota.XLSX by Martina Penati (11098665)

“…Notably, WM calves showed a decrease in beneficial taxa such as Faecalibacterium, with a concomitant increase in potential pathogens such as Campylobacter, Pseudomonas, and Chlamydophila spp. …”

Image_1_Feeding Pre-weaned Calves With Waste Milk Containing Antibiotic Residues Is Related to a Higher Incidence of Diarrhea and Alterations in the Fecal Microbiota.PDF by Martina Penati (11098665)

“…Notably, WM calves showed a decrease in beneficial taxa such as Faecalibacterium, with a concomitant increase in potential pathogens such as Campylobacter, Pseudomonas, and Chlamydophila spp. …”

Image_2_Feeding Pre-weaned Calves With Waste Milk Containing Antibiotic Residues Is Related to a Higher Incidence of Diarrhea and Alterations in the Fecal Microbiota.TIFF by Martina Penati (11098665)

“…Notably, WM calves showed a decrease in beneficial taxa such as Faecalibacterium, with a concomitant increase in potential pathogens such as Campylobacter, Pseudomonas, and Chlamydophila spp. …”

Image_3_Feeding Pre-weaned Calves With Waste Milk Containing Antibiotic Residues Is Related to a Higher Incidence of Diarrhea and Alterations in the Fecal Microbiota.TIFF by Martina Penati (11098665)

“…Notably, WM calves showed a decrease in beneficial taxa such as Faecalibacterium, with a concomitant increase in potential pathogens such as Campylobacter, Pseudomonas, and Chlamydophila spp. …”

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study by Bram. P. Prins (3165489)

“…Further, we found that a standardized CRP polygenic risk score (CRP_<i>PRS</i>) at <i>p-</i>value thresholds of 1 × 10⁻⁴, 0.001, 0.01, 0.05, and 0.1 using individual-level data also showed a protective effect (OR < 1.00) against schizophrenia; the first CRP_<i>PRS</i> (built of SNPs with <i>p</i> < 1 × 10⁻⁴) showed a statistically significant (<i>p <</i> 2.45 × 10⁻⁴) protective effect with an OR of 0.97 (95% CI 0.95–0.99). …”

Supplementary file 1_Differential susceptibility to prenatal stress exposure in serotonin transporter-deficient female mice—an epigenetic exploration.docx by Magdalena T. Weidner (6689105)

“…</p>Results<p>Dependent on the 5-Htt genotype, PS offspring showed decreased social behaviour in the 3-chamber sociability test. …”

Data Sheet 2_Differential susceptibility to prenatal stress exposure in serotonin transporter-deficient female mice—an epigenetic exploration.pdf by Magdalena T. Weidner (6689105)

“…</p>Results<p>Dependent on the 5-Htt genotype, PS offspring showed decreased social behaviour in the 3-chamber sociability test. …”

Data Sheet 1_Differential susceptibility to prenatal stress exposure in serotonin transporter-deficient female mice—an epigenetic exploration.pdf by Magdalena T. Weidner (6689105)

“…</p>Results<p>Dependent on the 5-Htt genotype, PS offspring showed decreased social behaviour in the 3-chamber sociability test. …”

Table 1_Differential susceptibility to prenatal stress exposure in serotonin transporter-deficient female mice—an epigenetic exploration.xlsx by Magdalena T. Weidner (6689105)

“…</p>Results<p>Dependent on the 5-Htt genotype, PS offspring showed decreased social behaviour in the 3-chamber sociability test. …”