Image_4_Ketamine-Treatment During Late Adolescence Impairs Inhibitory Synaptic Transmission in the Prefrontal Cortex and Working Memory in Adult Rats.TIF by Miguel Ángel Pérez (7280720)

“…Here, we examined the effect of ketamine (Ket) administration during late adolescence in rats on inhibition in the mPFC-, ventral HPC (vHPC), and A1. …”

Electrophysiological characterisation of α-MHCcells by Michael Xavier Doss (30403)

“…Statistical analysis of the effects of carbachol (1 μmol/l) and isoproterenol (1 μmol/l) on the spontaneous AP frequency. Carbachol caused a decrease whereas isoproterenol increased the spontaneous AP frequency.…”

Data_Sheet_1_Case Report: Event-Related Desynchronization Observed During Volitional Swallow by Electroencephalography Recordings in ALS Patients With Dysphagia.pdf by Akari Ogawa (12093176)

“…It is caused by degeneration of both the bulbar motor neurons and cortical motoneurons projecting to the oropharyngeal areas. A previous report showed decreased event-related desynchronization (ERD) in the medial sensorimotor areas in ALS dysphagic patients. …”

Ketamine to enhance methadone treatment retention in patients with opioid use disorder and co-morbid depression by Peter Manza (8493354)

“…</p> <p><i>Methods:</i> Participants underwent a 2-week ketamine regimen (0.5 mg/kg infusion over 40 min, three times per week for 2 weeks).…”

Model: Mph1 promotes HR by enhancing resection and thereby inhibits NHEJ. by Sarah Luke-Glaser (147362)

“…We propose that Mph1 leads to increased telomeric resection at a dysfunctional telomere and thereby promotes recombination, <i>i.e.…”

Image_2_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.JPEG by Bradley S. Hollidge (14113539)

“…<p>Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases. Here, we characterize and compare the temporal profile of transgene expression after bilateral injections into the mouse striatum of rAAV9 encoding GFP under the control of either a ubiquitous promoter (CAG), or the neuron-specific human synapsin (hSyn) and CamKII promoters. …”

Image_4_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.JPEG by Bradley S. Hollidge (14113539)

“…<p>Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases. Here, we characterize and compare the temporal profile of transgene expression after bilateral injections into the mouse striatum of rAAV9 encoding GFP under the control of either a ubiquitous promoter (CAG), or the neuron-specific human synapsin (hSyn) and CamKII promoters. …”

Differing Causes of Lactic Acidosis and Deep Breathing in Cerebral Malaria and Severe Malarial Anemia May Explain Differences in Acidosis-Related Mortality by Nathan R. Brand (3185376)

“…In contrast, in SMA, LA was associated with a decreased hemoglobin level, but was not associated with PfHRP2 concentration or platelet count. …”

Table_1_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.pdf by Bradley S. Hollidge (14113539)

“…<p>Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases. Here, we characterize and compare the temporal profile of transgene expression after bilateral injections into the mouse striatum of rAAV9 encoding GFP under the control of either a ubiquitous promoter (CAG), or the neuron-specific human synapsin (hSyn) and CamKII promoters. …”

Image_3_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.JPEG by Bradley S. Hollidge (14113539)

“…<p>Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases. Here, we characterize and compare the temporal profile of transgene expression after bilateral injections into the mouse striatum of rAAV9 encoding GFP under the control of either a ubiquitous promoter (CAG), or the neuron-specific human synapsin (hSyn) and CamKII promoters. …”

Image_1_Kinetics and durability of transgene expression after intrastriatal injection of AAV9 vectors.JPEG by Bradley S. Hollidge (14113539)

“…<p>Understanding the kinetics and durability of AAV-mediated transgene expression in the brain is essential for conducting basic neuroscience studies as well as for developing gene therapy approaches for CNS diseases. Here, we characterize and compare the temporal profile of transgene expression after bilateral injections into the mouse striatum of rAAV9 encoding GFP under the control of either a ubiquitous promoter (CAG), or the neuron-specific human synapsin (hSyn) and CamKII promoters. …”

Divergence in root functional trait variation for yield improvement by Du (17111761)

“…However, there are few studies integrating the effects of physiological and anatomical traits relevant to carbon allocation and water transport in roots on yield.We performed a global scale data analysis to quantify the ecological effects of root functional traits on yield under abiotic stress. …”

The Roles of Parathyroid Hormone-Like Hormone during Mouse Preimplantation Embryonic Development by Lei Guo (36221)

“…<div><p>Parathyroid hormone-like hormone (PTHLH) was first identified as a parathyroid hormone (PTH)-like factor responsible for humoral hypercalcemia in malignancies in the 1980s. …”

Effects of isometric handgrip training in patients with cardiovascular disease: rationale and design of the ISOPRESS network by Breno Q. Farah (840797)

“…However, several gaps in the literature still need to be addressed. Thus, we designed the ISOPRESS network group, which consists of a task force of different research groups aimed at analyzing the effects of isometric handgrip training on different contexts, parameters, and populations. …”

MicroRNA-9 restrains the sharp increase and boost apoptosis of human acute myeloid leukemia cells by adjusting the Hippo/YAP signaling pathway by Guoqing Wang (128352)

“…This study focuses on the effects of miR-9 on the regulation of AML cells and their related signaling pathways. We found that the expression of miR-9 was significantly decreased in four AML cell lines (THP-1, HL-60, TF-1 and KG-1) compared with the human normal bone marrow cells (HS-5). …”

Supplementary Material for: Clinicopathological Characteristics, Surgery and Survival Outcomes of Patients with Duodenal Gastrointestinal Stromal Tumors by Sugase T. (2871863)

“…<i>Background:</i> Duodenal gastrointestinal stromal tumors (GISTs) are a rare subset of GISTs (3-5%), and their clinicopathological features have not been fully described. …”

Video 1_Experimental feasibility of personalized functional neuromuscular stimulation stepping patterns developed in silico.mp4 by Holly Warner (21811256)

“…Relative to the manually tuned pattern, the model-optimized stimulation decreased upper extremity effort by 10.5% during left swing. …”

PATHOLOGICAL FRACTURES DUE TO BONE METASTASES FROM LUNG CANCER: RISK FACTORS AND SURVIVAL by Marcelo Bragança dos Reis Oliveira (5938733)

“…Objectives: To identify risk factors associated with the occurrence of pathological fractures in patients with lung cancer and to determine survival. Methods: We conducted a retrospective cohort study with 407 lung carcinoma patients diagnosed between 2006 and 2015. …”

S=0.mp4 from Sodium chloride inhibits effective bubbly drag reduction in turbulent bubbly Taylor–Couette flows by Luuk J. Blaauw (14275430)

“…Salts present in the working fluid inhibit coalescence events, resulting in smaller bubbles in the flow and with that, decreasing the drag reduction. Above a critical salinity, increasing the salinity has no further effect on the bubble sizes in the flow and thus the drag experienced by the flow. …”

Data for figure 4 from Sodium chloride inhibits effective bubbly drag reduction in turbulent bubbly Taylor–Couette flows by Luuk J. Blaauw (14275430)

“…Salts present in the working fluid inhibit coalescence events, resulting in smaller bubbles in the flow and with that, decreasing the drag reduction. Above a critical salinity, increasing the salinity has no further effect on the bubble sizes in the flow and thus the drag experienced by the flow. …”