Data Sheet 1_The global, regional, and national patterns of change in the burden of edentulism, 1990–2021: an analysis of the global burden of disease study 2021 and forecast to 20... by Xiaolan Zhong (701647)

“…However, joinpoint regression revealed a recent upward trend from 2015 to 2021. The age group with the highest incidence increased by 5 years; the 75–79 group had the highest rate in 2021. …”

Epigenetic Inactivation of EFEMP1 Is Associated with Tumor Suppressive Function in Endometrial Carcinoma by Tingting Yang (166111)

“…EFEMP1 promoter was hypermethylated in endometrial carcinoma tissues (67%) as compared to normal tissue (10%) and down-regulation of EFEMP1 was associated with promoter hypermethylation. Treatment with 5-aza-2′-deoxycytidine (5-aza-dC) and/or trichostatin A (TSA) altered EFEMP1 methylation status, and restored EFEMP1 expression. …”

DataSheet1_The Relationship Between Low-Density Lipoprotein Cholesterol and Progression of Mild Cognitive Impairment: The Influence of rs6859 in PVRL2.docx by Qianyi Xiao (3987308)

“…This study aims to investigate the effects of cholesterol and genetic risk factors on progression of mild cognitive impairment (MCI) to AD.</p><p>Methods: We prospectively followed 316 MCI participants aged ≥50 years with a baseline cholesterol profile and SNP genotyping data for 4.5 years on average in a sub-cohort of the Shanghai Aging Study. …”

Kinetics of Microbial Translocation Markers in Patients on Efavirenz or Lopinavir/r Based Antiretroviral Therapy by Jan Vesterbacka (277457)

“…<div><h3>Objectives</h3><p>We investigated whether there are differences in the effects on microbial translocation (MT) and enterocyte damage by different antiretroviral therapy (ART) regimens after 1.5 years and whether antibiotic use has impact on MT. …”

Recurrence between the AIs and tamoxifen groups. by Chuan-Hsun Chang (20348083)

“…</p><p>Results</p><p>The average age was 65.1 years, with a median follow-up time of 5.7 years and a median duration of endocrine therapy of 4.5 years. …”

Data_Sheet_1_In-hospital major bleeding in patients with acute coronary syndrome medically treated with dual anti-platelet therapy: Associated factors and impact on mortality.docx by Yihong Sun (442494)

“…Multivariable analysis showed advancing age (RR = 1.52 for every 10 years increase, 95% CI: 1.13, 2.05), impaired renal function (RR = 1.79, 95% CI: 1.10, 2.92), use of fibrinolytic drugs (RR = 2.93, 95% CI: 1.55, 5.56), and severe diseases other than cardiovascular and renal diseases (RR = 5.56, 95% CI: 1.10, 28.07) were associated with increased risk of major bleeding, whereas using renin–angiotensin system inhibitors (RR = 0.54, 95% CI: 0.36, 0.81) was associated with decreased risk of major bleeding. …”

Demographic data of the study cohort. by Chuan-Hsun Chang (20348083)

“…</p><p>Results</p><p>The average age was 65.1 years, with a median follow-up time of 5.7 years and a median duration of endocrine therapy of 4.5 years. …”

Muscle fiber hypertrophy in response to 6 weeks of high-volume resistance training in trained young men is largely attributed to sarcoplasmic hypertrophy by Cody T. Haun (4183900)

“…Phalloidin-actin staining similarly revealed actin concentrations per fiber decreased from PRE to W6. Proteomic analysis of the sarcoplasmic fraction from PRE to W6 indicated 40 proteins were up-regulated (p<0.05), KEGG analysis indicated that the glycolysis/gluconeogenesis pathway was upregulated (FDR sig. <0.001), and DAVID indicated that the following functionally-annotated pathways were upregulated (FDR value <0.05): a) glycolysis (8 proteins), b) acetylation (23 proteins), c) gluconeogenesis (5 proteins) and d) cytoplasm (20 proteins). …”

Electromechanical Properties and Spontaneous Response of the Current in InAsP Nanowires by Jong Hoon Lee (245610)

“…Upon increasing the tensile strain, the electrical current in the NWs increases linearly, and the piezoresistance gradually decreases nonlinearly. By analyzing the space-charge-limited <i>I–V</i> curves, we show that the electromechanical response is due to a mobility that increases with strain. …”

Gene expression levels of the intracellular localized TLRs <i>Tlr3</i>, <i>Tlr7</i>, <i>Tlr8</i>, and <i>Tlr9</i> in different HF models of diverse etiology. by Peter Moritz Becher (192666)

“…In the heart failure model caused by chronic AngII-infusion for 21 days (shown in yellow) only the intracellular localized <i>Tlr3</i> displayed a significant decrease when compared to their controls. …”

Image_2_Trehalose alleviates salt tolerance by improving photosynthetic performance and maintaining mineral ion homeostasis in tomato plants.TIF by Yan Yang (33204)

“…<p>Trehalose (Tre), which was an osmoprotective or stabilizing molecule, played a protective role against different abiotic stresses in plants and showed remarkable perspectives in salt stress. …”

Raw data. by Guohui Zhao (4668682)

“…Control scores were 4.90±0.61,5.46±0.84, and 4.64±0.69 for the respective tensions. …”

Serum IL-1Ra from intra-colonic inhibits IL-1-induced thymocyte proliferation by Stefano Porzio (5085)

“…</p> Co-stimulation of murine thymocyte proliferation by IL-1β was assessed in cultures of C3H/HeJ thymocytes stimulated with a suboptimal concentration of PHA (1.5 μg/ml) in the absence (zero control; empty column) or in the presence of IL-1β (solid column). …”

Image_3_Impact of heat and high-moisture pH treatments on starch digestibility, phenolic composition, and cell bioactivity in sorghum (Sorghum bicolor L. Moench) flour.JPEG by Jaymi Peterson (19350685)

“…The measured 3-deoxyanthocyanidins experienced a significant decrease (p < 0.0001), while certain flavonoids increased significantly (p < 0.05) after heating for 30 min or longer. …”

Image_3_Effects of combined ciprofloxacin and Neulasta therapy on intestinal pathology and gut microbiota after high-dose irradiation in mice.tif by Timothy S. Horseman (11105298)

“…Combined therapy of Neulasta and ciprofloxacin induced a decrease in Shannon diversity and resulted in unique taxonomic profiles early post-irradiation, returning closer to vehicle-treated levels over time, but persistent increases in Akkermansia and Bacteroides compared to Neulasta alone.…”

Histone acetylation and E2F1 binding at the <i>BRCA1</i> and <i>RAD51</i> promoter regions. by Hideaki Ogiwara (18358)

“…<p>(<b>A, B</b>) CBP and p300 recruitment to the <i>BRCA1</i> and <i>RAD51</i> promoter regions. …”

Table_1_Gastrointestinal digestibility insights of different levels of coated complex trace minerals supplementation on growth performance of yellow-feathered broilers.DOCX by Chuanbin Chen (11385608)

“…<p>This study was designed to evaluate the optimum additional level of coated complex trace minerals (TMs) and its impacts on the growth performance of broilers through measurement of digestibility of nutrients and intestinal development. In a 56-day trial, a total of 360 one-day-old male yellow-feathered broilers were randomly divided into six dietary treatment groups. …”

DataSheet_1_CCN3 Signaling Is Differently Regulated in Placental Diseases Preeclampsia and Abnormally Invasive Placenta.docx by Liyan Duan (8736837)

“…The decrease of CCN3 level is associated with an increase in p53, Cyclin E1 and pRb protein expression, whereas the level of cleaved Notch-1, p21, Cyclin D1, pFAK, pAKT, and pmTOR protein decreased. …”

Table_1_Effects of combined ciprofloxacin and Neulasta therapy on intestinal pathology and gut microbiota after high-dose irradiation in mice.DOCX by Timothy S. Horseman (11105298)

“…Combined therapy of Neulasta and ciprofloxacin induced a decrease in Shannon diversity and resulted in unique taxonomic profiles early post-irradiation, returning closer to vehicle-treated levels over time, but persistent increases in Akkermansia and Bacteroides compared to Neulasta alone.…”

Isostructural <i>neo</i>-Pentoxide Derivatives of Group 3 and the Lanthanide Series Metals for the Production of Ln₂O₃ Nanoparticles by Timothy J. Boyle (1455829)

“…The synthesis and characterization of a series of <i>neo-</i>pentoxide (OCH₂C(CH₃)₃ or ONep) derivatives of group 3 and the lanthanide (Ln) series' metals were undertaken via an amide/alcohol exchange route. …”