Investigating specificity of the anti-hypertensive inhibitor WNK463 against With-No-Lysine kinase family isoforms via multiscale simulations by Nisha A. Jonniya (6629630)

“…<p>The With-No-Lysine (WNK) kinase family plays a significant role in regulating cation-chloride cotransporters, blood pressure and body fluid homeostasis. …”

Data_Sheet_1_Staphylococcus aureus Cell Wall Biosynthesis Modulates Bone Invasion and Osteomyelitis Pathogenesis.PDF by Elysia A. Masters (9553742)

“…Here, we investigated select S. aureus cell wall synthesis mutants (Δpbp3, Δatl, and ΔmreC) and surface adhesin mutants (ΔclfA and ΔsasC) for nanopore propagation in vitro and osteomyelitis pathogenesis in vivo. …”

Table1.DOCX by Jonathan A. Botha (4864381)

“…During December the diet was comprised almost exclusively of anchovy (Engraulis encrasicolus), the proportion of which had decreased significantly in the diet by January. This was mirrored by a substantial increase in the proportion of saury (Scomberesox saurus). …”

Influence of in Vitro Hydrolytic Degradation on the Morphology and Crystallization Behavior of Poly(<i>p</i>-dioxanone) by Marcos A. Sabino (2723167)

“…Through the use of the Thomson−Gibbs equation, we obtained a value of 166 erg/cm² for the fold surface free energy of PPDX. …”

<em>Foxa1</em> and <em>Foxa2</em> Are Required for Formation of the Intervertebral Discs by Jennifer A. Maier (278698)

“…However, embryonic lethality and the absence of the notochord in <em>Foxa2</em> null mice have precluded the study of potential roles these genes may play during IVD formation. Using a conditional <em>Foxa2</em> allele in conjunction with a tamoxifen-inducible <em>Cre</em> allele (<em>ShhcreER^T2</em>), we removed <em>Foxa2</em> from the notochord of E7.5 mice null for <em>Foxa1</em>. …”

Reproducing on Time When Temperature Varies: Shifts in the Timing of Courtship by Fiddler Crabs by Kecia A. Kerr (564973)

“…The mechanisms that allow such precision in the timing of the production of young are poorly known. A preliminary study suggested that when temperature decreases, <i>U. terpsichores</i> mate earlier in the tidal amplitude cycle such that larvae are released at the appropriate time. …”

Neurodevelopmental Disruption of Cortico-Striatal Function Caused by Degeneration of Habenula Neurons by Young-A Lee (223034)

“…</p> <h3>Methodology/Principal Findings</h3><p>Using a battery of behavioral, anatomical, and biochemical assays, we examined the impacts of neonatal damage in the habenula on neurodevelopmental sequelae of the prefrontal cortex (PFC) and nucleus accumbens (NAcc) and associated behavioral deficits in rodents. …”

Table_5_Native Herbivores Improve Sexual Propagation of Threatened Staghorn Coral Acropora cervicornis.XLSX by Joseph A. Henry (7902233)

“…Growing coral with native herbivores may represent a strategy for increased efficiency. We tested A. cervicornis recruits raised in replicate aquaria with identical densities of juvenile Lithopoma americanum or juvenile Batillaria minima snails plus a no-snail control. …”

An Sp1/Sp3 Binding Polymorphism Confers Methylation Protection by Yanis A. Boumber (195910)

“…In search for factors that influence RIL hypermethylation, we found a 12-bp polymorphic sequence around its transcription start site that creates a long allele. …”

Data_Sheet_1_Pan-cerebral sodium elevations in vascular dementia: Evidence for disturbed brain-sodium homeostasis.docx by Sasha A. Philbert (12012338)

“…We found novel evidence for elevated wet-weight cerebral sodium levels in VaD brain tissue in six out of the seven regions analyzed. …”

ZIP4H (TEX11) Deficiency in the Mouse Impairs Meiotic Double Strand Break Repair and the Regulation of Crossing Over by Carrie A. Adelman (43553)

“…Analysis of spermatocytes revealed a delay in meiotic double strand break repair and decreased crossover formation as inferred from DMC1 and MLH1 staining patterns, respectively. …”

Table_1_Native Herbivores Improve Sexual Propagation of Threatened Staghorn Coral Acropora cervicornis.XLSX by Joseph A. Henry (7902233)

“…Growing coral with native herbivores may represent a strategy for increased efficiency. We tested A. cervicornis recruits raised in replicate aquaria with identical densities of juvenile Lithopoma americanum or juvenile Batillaria minima snails plus a no-snail control. …”

Manipulation of Behavioral Decline in <em>Caenorhabditis elegans</em> with the Rag GTPase <em>raga-1</em> by Matthew A. Schreiber (248264)

“…Using <em>Caenorhabditis elegans</em>, we have developed a model of declining neuromuscular function and conducted a screen for increased behavioral activity in aged animals. …”

XPRESSyourself: Enhancing, standardizing, and automating ribosome profiling computational analyses yields improved insight into data by Jordan A. Berg (2838251)

“…This technique has been available for a decade, yet the current state and standardization of publicly available computational tools for these data is bleak. …”

Go-6976 Reverses Hyperglycemia-Induced Insulin Resistance Independently of cPKC Inhibition in Adipocytes by Katherine A. Robinson (645068)

“…Here, we demonstrate that treatment with Go-6976, a widely used “specific” inhibitor of cPKCs, alleviates hyperglycemia-induced insulin resistance. …”

Process and Workflow for Preparation of Disparate Mouse Tissues for Proteomic Analysis by Sarah A. Michaud (4062115)

“…Concentrations of nonblood proteins were largely unchanged, although significantly higher variances were observed for proteins from the perfused lung, indicating that perfusion may not be suitable for this organ. We present a simple yet effective tissue processing workflow consisting of harvest of fresh nonperfused tissue, novel lyophilization and homogenization by bead-beating, and protein precipitation. …”

Table_2_Native Herbivores Improve Sexual Propagation of Threatened Staghorn Coral Acropora cervicornis.XLSX by Joseph A. Henry (7902233)

“…Growing coral with native herbivores may represent a strategy for increased efficiency. We tested A. cervicornis recruits raised in replicate aquaria with identical densities of juvenile Lithopoma americanum or juvenile Batillaria minima snails plus a no-snail control. …”

Data_Sheet_2_Pan-cerebral sodium elevations in vascular dementia: Evidence for disturbed brain-sodium homeostasis.xlsx by Sasha A. Philbert (12012338)

“…We found novel evidence for elevated wet-weight cerebral sodium levels in VaD brain tissue in six out of the seven regions analyzed. …”

State dependence of stimulus-induced variability tuning in macaque MT by Joseph A. Lombardo (5851199)

“…<div><p>Behavioral states marked by varying levels of arousal and attention modulate some properties of cortical responses (e.g. average firing rates or pairwise correlations), yet it is not fully understood what drives these response changes and how they might affect downstream stimulus decoding. Here we show that changes in state modulate the tuning of response variance-to-mean ratios (Fano factors) in a fashion that is neither predicted by a Poisson spiking model nor changes in the mean firing rate, with a substantial effect on stimulus discriminability. …”

Supplementary Material for: The role of transbronchial cryobiopsy in the detection of pulmonary GvHD. by Sadowska-Klasa A. (20361480)

“…Purpose of the study We investigated the incidence of chronic pulmonary complications in allogeneic hematopoietic cell transplantation (allo-HCT) recipients and analyzed the role of transbronchial cryobiopsy (cryoTBB) as a tool to determine the nature of pulmonary changes and to guide clinical decisions. …”