MBIC50 and MBEC50 values (µg/mL) of synthesized 1,2,3,5-tetrazine derivatives against bacteria pathogen strains. by Jean Paul Dzoyem (6424445)

Subjects:

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

Anticancer Activity Expressed by a Library of 2,9-Diazaperopyrenium Dications by Karel J. Hartlieb (1367880)

“…Although many promising chemotherapeutics have been developed upon the basis of polyaromatic DNA intercalating systems, these candidates did not proceed past clinical trials on account of their dose-limiting toxicity. Herein, we discuss an alternative, water-soluble class of polyaromatic compounds, the 2,9-diazaperopyrenium dications, and report <i>in vitro</i> cell studies for a library of these dications. …”

LS-PGC-1β^−/− mice exhibit decreased expression of TCA and ETC enzymes and mtDNA content. by Kari T. Chambers (106919)

Pairwise correlations of excitatory neurons in APP/PS1 mice are decreased in dCA1, but increased in vCA1. by Udaysankar Chockanathan (18510288)

Decreased dendritic spine density and mEPSC amplitude in the DG of Arf4^+/− mice compared to WT mice. by Sachi Jain (108277)

Increased body weight and decreased expansion of pro-inflammatory CD4+ T-cells from blood in Tg-HD5 rats. by Osiris Marroquin Belaunzaran (224031)

S1 File - by Chantelle M. de Vet (16535257)

“…The student’s RV-GLS consistency was poor during the first 25 measurements, moderate-to good during the second 25 measurements and again poor-to-moderate during the final 50 measurements. Repeated measurements analysis showed a significant decrease in variability of the LV- and RV-GLS score differences between the expert and trainees over time (<i>p</i>_adj<0.001), which was not significantly different between trainees. …”

Inhibition of PI3K activity decreases uptake of Opa_CEA-expressing gonococci via CEACAM1. by Maike Voges (154488)

GLS analysis with 2D-STE software. by Chantelle M. de Vet (16535257)

“…The student’s RV-GLS consistency was poor during the first 25 measurements, moderate-to good during the second 25 measurements and again poor-to-moderate during the final 50 measurements. Repeated measurements analysis showed a significant decrease in variability of the LV- and RV-GLS score differences between the expert and trainees over time (<i>p</i>_adj<0.001), which was not significantly different between trainees. …”

Loss of SLC9A3 decreases CFTR protein and causes obstructed azoospermia in mice by Ya-Yun Wang (175049)

“…In the present study, we found that CFTR expression was dramatically decreased in the epididymis and vas deferens of <i>Slc9a3</i> knockout mice. …”

Relative abundance for nine resident species that were detected significantly decreased from natural reference to e-waste polluted zone. by Qiang Zhang (45005)

“…Relative abundance is expressed as mean number of birds detected within 50 m per point at each site. …”

Quercetin decreases H₂O₂-induced intracellular ROS level in mouse zygotes. by Sha Yu (525972)

Necdin deficiency decreases <i>p16</i> expression and increases <i>Cdk1</i> expression in the embryonic neocortex. by Ryohei Minamide (505053)

Blockade of kinin B₁R in the chronic disease phase decreased the clinical symptoms and neuroinflammation in the EAE model. by Rafael C. Dutra (205755)

Silencing of SphK1, but not SphK2, decreases HPAEC migration by S1P in wound healing ECIS assay. by Evgeny V. Berdyshev (307465)

Image_1_Decreased Compressional Sound Velocity Is an Indicator for Compromised Bone Stiffness in X-Linked Hypophosphatemic Rickets (XLH).TIFF by Adalbert Raimann (469799)