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20021
Pirt plays a role in mast cell-dependent itch.
Published 2013“…<p>(<b>A</b>, <b>B</b>) In an allergy model, ovalbumin (50 µg) induces less scratching in <i>Pirt<sup>−/−</sup></i> (n = 11) and SASH (n = 7) mice compared to WT controls (n = 8). …”
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20022
Image_1_MiR224-5p Inhibitor Restrains Neuronal Apoptosis by Targeting NR4A1 in the Oxygen-Glucose Deprivation (OGD) Model.TIF
Published 2020“…<p>This study was designed to investigate the molecular mechanism of stroke and to explore the effect of miR-224-5p in hypoxic cortical neurons. Firstly, we established a middle cerebral artery occlusion (MCAO) model with Sprague–Dawley rats. …”
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20023
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20024
Image_2_RANKL-Induced Btn2a2 – A T Cell Immunomodulatory Molecule – During Osteoclast Differentiation Fine-Tunes Bone Resorption.jpeg
Published 2021“…Moreover, in rheumatoid arthritis patients and experimental arthritis, we detected significantly decreased serum levels of the secreted soluble Btn2a2 protein. …”
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20025
Image_1_RANKL-Induced Btn2a2 – A T Cell Immunomodulatory Molecule – During Osteoclast Differentiation Fine-Tunes Bone Resorption.jpeg
Published 2021“…Moreover, in rheumatoid arthritis patients and experimental arthritis, we detected significantly decreased serum levels of the secreted soluble Btn2a2 protein. …”
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20026
Data_Sheet_1_iProm-phage: A two-layer model to identify phage promoters and their types using a convolutional neural network.docx
Published 2022“…In this study we proposed a two layer model called “iProm-phage” for the prediction and classification of phage promoters. …”
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20027
Transport Distance of Invertebrate Environmental DNA in a Natural River
Published 2014“…We detected <i>D. longispina</i> at all locations and across two time points (July and October); whereas with <i>U. tumidus,</i> we observed a decreased detection rate and did not detect its eDNA after 9.1 km. …”
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20028
The GAP Activity of Type III Effector YopE Triggers Killing of <i>Yersinia</i> in Macrophages
Published 2014“…In addition to conserved microbial patterns, the mammalian immune system may recognize distinct pathogen-induced processes through a mechanism which is poorly understood. Previous studies have shown that a type III secretion system (T3SS) in <i>Yersinia pseudotuberculosis</i> leads to decreased survival of this bacterium in primary murine macrophages by unknown mechanisms. …”
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20029
Patterns and Variation in Benthic Biodiversity in a Large Marine Ecosystem
Published 2015“…We specifically asked whether marine biodiversity followed a strict latitudinal gradient, and if these latitudinal patterns varied across depth, in different benthic substrates, and over ecological time scales. …”
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20030
Agent movement, interaction rules, and resulting trajectories in a box.
Published 2021“…<b>G</b> Cross-sectional distribution of agents (<i>N</i> = 1000), simulated in a channel with a width and height of 50 μm. Agent density increases towards boundaries and corners. …”
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20031
Table2_The Impact of a National Stewardship Policy on the Usage Patterns of Key Monitoring Drugs in a Tertiary Teaching Hospital: An Interrupted Time Series Analysis.docx
Published 2022“…A similar decrease in spending was seen in the post-implementation period, with a trend of $4,682 less total spending on medications in those months compared to the pre-implementation trend (p = 0.003). …”
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20032
Table1_The Impact of a National Stewardship Policy on the Usage Patterns of Key Monitoring Drugs in a Tertiary Teaching Hospital: An Interrupted Time Series Analysis.docx
Published 2022“…A similar decrease in spending was seen in the post-implementation period, with a trend of $4,682 less total spending on medications in those months compared to the pre-implementation trend (p = 0.003). …”
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20033
Two Fagan nomograms for the (genetic) evidence in a judicial context
Published 2014“…Without proper instructions to a court, Bayes’ rule is either applied subconsciously by the judge, or prior probability is, by default, assigned a flat 50% probability by a forensic expert. …”
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20034
Evidence of saturation of protein fold space as a function of time.
Published 2009“…All cases in which FATCAT algorithm found at least 50 equivalent residues superimposed with C<sub>α</sub> RMSD <3 Å were regarded as putative cases of “significant partial similarity” and were subject to visual verification. …”
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20035
Additive Effects of Millimeter Waves and 2-Deoxyglucose Co-Exposure on the Human Keratinocyte Transcriptome
Published 2016“…We found that the 2dG treatment decreased the cellular ATP content and induced a high modification in the transcriptome (632 coding genes). …”
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20036
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20037
Learning to use past evidence in a sophisticated world model
Published 2019“…We accounted for their behaviour using a Hidden Markov Model, in which recent observations are integrated with evidence from the past. …”
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20038
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20039
Emergence as a functions of increasing HIV/AIDS prevalence and adherence.
Published 2019“…<p>3a. In Using Swaziland’s low TB condition as an example, and assuming 95% antibiotic adherence [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0212969#pone.0212969.ref025" target="_blank">25</a>], we found that, as HIV/AIDS prevalence increases from zero to 30%, we observe a corresponding increase in expected population-wide emergence of antibiotic resistance. …”
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20040