Implementation of a National Reference Laboratory for Buruli Ulcer Disease in Togo by Marcus Beissner (139059)

“…Compared to a previous study, the rate of BUD patients with non-ulcerative lesions increased from 37% to 50%, the mean duration of disease before clinical diagnosis decreased significantly from 182.6 to 82.1 days among patients with ulcerative lesions, and the percentage of category III lesions decreased from 30.3% to 19.2%.…”

Redefining Molecular Amphipathicity in Reversing the “Coffee-Ring Effect”: Implications for Single Base Mutation Detection by Chi Huang (4566721)

“…The “coffee ring effect” is a natural phenomenon wherein sessile drops leave ring-shaped structures on the solid surfaces upon drying. …”

Redefining Molecular Amphipathicity in Reversing the “Coffee-Ring Effect”: Implications for Single Base Mutation Detection by Chi Huang (4566721)

“…The “coffee ring effect” is a natural phenomenon wherein sessile drops leave ring-shaped structures on the solid surfaces upon drying. …”

Model parameters. by Martijn C. Sierksma (11608174)

“…During the following weeks, both these latencies and their interaural difference decreased. A computational model indicated that spike timing-dependent plasticity can underlie this fine-tuning. …”

Supplementary Material for: Hyperfunctioning Papillary Thyroid Carcinoma with a <b><i>BRAF</i></b> Mutation: The First Case Report and a Literature Review by Shinkai S. (10260734)

“…<b><i>Discussion and Conclusions:</i></b> We report a case of hyperfunctioning PTC with a <i>BRAF</i> V600E mutation for the first time. …”

D-TRP(8)-γMSH Prevents the Effects of Endotoxin in Rat Skeletal Muscle Cells through TNFα/NF-KB Signalling Pathway - Fig 9 by Ana Belén Gómez-SanMiguel (3170115)

“…<p>Effect of D-Trp(8)-γMSH (0, 50 or 200 nM) on; phospho-NF-κB(p65)Ser276 (A), NF-κB(p65) (B), phospho-Akt (C) Akt (D), IGF-I mRNA (E) and MHC I mRNA (F) in L6 myotubes cell cultures incubated with TNFα (10 μg/ml) or DMEM. …”

A Prevalent Variant in <em>PPP1R3A</em> Impairs Glycogen Synthesis and Reduces Muscle Glycogen Content in Humans and Mice by David B Savage (61670)

“…Human genetic disorders primarily affecting skeletal muscle glycogen turnover are well-recognised, but rare. We previously reported that a frameshift/premature stop mutation in <em>PPP1R3A</em>, the gene encoding R_GL, a key regulator of muscle glycogen metabolism, was present in 1.36% of participants from a population of white individuals in the UK. …”

(A) CD45 cells express Sema4D by Jose Rafael Sierra (50652)

“…(right) As shown, ∼85% of the leukocytes express Sema4D. Error bars indicate mean ± SD. *, P < 0.0001. Bar, 50 μm. (B) WT-derived bone marrow cells rescue tumor burden. …”

The B-Raf^V600E-Twist axis regulates miR-10b expression in melanoma. by Ila Datar (433874)

Dendritic Hydrogels Induce Immune Modulation in Human Keratinocytes and Effectively Eradicate Bacterial Pathogens by Yanmiao Fan (11552099)

“…Biomaterials that have inherent antibacterial properties and do not require the use of antibiotics present an attractive and feasible avenue to achieve this goal. Herein, we demonstrate the effect of a new class of cationic hydrogels based on amino-functional hyperbranched dendritic–linear–dendritic copolymers (HBDLDs) exhibiting excellent antimicrobial activity toward a wide range of clinical Gram-positive and Gram-negative bacteria, including drug-resistant strains isolated from wounds. …”

Demographic data. by Narisa Rattanalert (21445983)

“…Deliberate practice is an instructional model designed to improve performance by engaging trainees in structured, repetitive practice with immediate feedback provided by supervisors. We developed a multifaceted simulation informed by deliberate practice and tested the hypothesis that trainee skills and reported confidence would increase after training. …”

Dynamical models of all Intrinsic currents. by Muhammad Mushtaq (788834)

“…To examine the effects of CLAS on spindles, we propose a biophysical thalamocortical model for slow oscillations (SOs) and sleep spindles. …”

Model parameters, their values, and descriptions. by Muhammad Mushtaq (788834)

“…To examine the effects of CLAS on spindles, we propose a biophysical thalamocortical model for slow oscillations (SOs) and sleep spindles. …”

Table_1_Visuomotor Adaptation Brain Changes During a Spaceflight Analog With Elevated Carbon Dioxide (CO2): A Pilot Study.docx by Ana Paula Salazar (9745565)

“…Additionally, we compare brain activity between this NASA campaign (30-day HDBR+CO₂) and a different campaign with a separate set of participants (60-day HDBR with normal atmospheric CO₂ levels, n = 8; 34.25 ± 7.9 years) to characterize the specific effects of CO₂. …”

Data_Sheet_1_Climate and Human-Driven Variability of Summer Hypoxia on a Large River-Dominated Shelf as Revealed by a Hypoxia Index.docx by Kui Wang (137551)

Data Sheet 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.xlsx by Susan Carroll (17468)

“…We hypothesise that a chaotic home environment will negatively impact flourishing, particularly for those who are highly sensitive, while being connected with nature will have a more positive effect on them. …”

Metabolic Responses of a Phototrophic Co-Culture Enriched from a Freshwater Sediment on Changing Substrate Availability and its Relevance for Biogeochemical Iron Cycling by Caroline Schmidt (723144)

“…Here, we exposed a phototrophic co-culture (<i>Rhodopseudomonas</i> sp. and <i>Chlorobium</i> sp.) that was isolated from a littoral freshwater sediment to a variety of substrates (acetate, Fe(II), or H₂) and followed the abundance of individual microbial partners based on their characteristic light absorption pattern. …”

Supplementary file 1_Flourishing as a highly sensitive person: a mixed method study on the role of nature connectedness and chaotic home environment.docx by Susan Carroll (17468)

“…We hypothesise that a chaotic home environment will negatively impact flourishing, particularly for those who are highly sensitive, while being connected with nature will have a more positive effect on them. …”

Microscopic Temperature Control Reveals Cooperative Regulation of Actin–Myosin Interaction by Drebrin E by Hiroaki Kubota (5798264)

“…Here, by applying the microscopic heat pulse method to actomyosin motility assay, the regulatory mechanism is examined from the room temperature up to 37 °C without a thermal denaturing of proteins. We show that the inhibition of actomyosin motility by drebrin E is eliminated immediately and reversibly during heating and depends on drebrin E concentration. …”

Microscopic Temperature Control Reveals Cooperative Regulation of Actin–Myosin Interaction by Drebrin E by Hiroaki Kubota (5798264)

“…Here, by applying the microscopic heat pulse method to actomyosin motility assay, the regulatory mechanism is examined from the room temperature up to 37 °C without a thermal denaturing of proteins. We show that the inhibition of actomyosin motility by drebrin E is eliminated immediately and reversibly during heating and depends on drebrin E concentration. …”