An Epoxyisoprostane Is a Major Regulator of Endothelial Cell Function by Wei Zhong (284774)

“…To determine the effect of EI on HAEC, we synthesized several stereoisomers of EI using a convergent approach from the individual optically pure building blocks, the epoxyaldehydes <b>5</b> and <b>6</b> and the bromoenones <b>14</b> and <b>16</b>. …”

Transient Pinning and Pulling: A Mechanism for Bending Microtubules by Ian A. Kent (3179607)

“…<div><p>Microtubules have a persistence length of the order of millimeters <i>in vitro</i>, but inside cells they bend over length scales of microns. …”

Competition between Influenza A Virus Genome Segments by Ivy Widjaja (128545)

“…How IAV balances the replication and transcription of its multiple genome segments is not understood. We developed a dual competition assay based on the co-transfection of firefly or <em>Gaussia</em> luciferase-encoding genome segments together with plasmids encoding IAV polymerase subunits and nucleoprotein. …”

Hepatitis C Virus Induced a Novel Apoptosis-Like Death of Pancreatic Beta Cells through a Caspase 3-Dependent Pathway by Qian Wang (32718)

“…However, the fact that HCV-infected cells exhibit a dilated, low-density nucleus with intact plasma and nuclear membrane indicates that a novel apoptosis-like death occurs. …”

Impact of Microbiota on Resistance to Ocular <i>Pseudomonas aeruginosa</i>-Induced Keratitis by Abirami Kugadas (3131940)

“…We find that in health, the presence of microbiota strengthened the ocular innate immune barrier by significantly increasing the concentrations of immune effectors in the tear film, including secretory IgA and complement proteins. …”

DNA Methylation as a Biomarker for Cardiovascular Disease Risk by Myungjin Kim (60778)

“…<div><h3>Background</h3><p>Elevated serum homocysteine is associated with an increased risk of cardiovascular disease (CVD). This may reflect a reduced systemic remethylation capacity, which would be expected to cause decreased genomic DNA methylation in peripheral blood leukocytes (PBL).…”

A Locally Linear Dynamic Strategy for Manifold Learning. by Weifan Wang (4669081)

“…For 10-30% noise, where the Hebbian network employs a local linear transform, learning selectively increases signal direction alignment (blue) while simultaneously decreasing noise direction alignment (orange). …”

Data_Sheet_1_A Pilot Study of a Parent Emotion Socialization Intervention: Impact on Parent Behavior, Child Self-Regulation, and Adjustment.PDF by Evalill Bølstad (11568514)

“…We conducted a controlled trial of the 6-week evidence-based TIK parenting program with 20 parents of preschool children aged 5–6 years and 19 wait-list controls. …”

Data Sheet 1_Acupuncture might enhance word recognition scores in a patient with hearing loss: a case report and literature review.pdf by Ke Fang (700094)

“…Upon admission, pure tone audiometry showed severe hearing loss across all frequencies in the left ear, with a word recognition score of 64. Based on the comprehensive examination results, we diagnosed him with sensorineural hearing loss (SNHL). …”

A Flp-SUMO hybrid recombinase reveals multi-layered copy number control of a selfish DNA element through post-translational modification by Chien-Hui Ma (259009)

“…In addition, the Flp protein is regulated by the host’s post-translational modification machinery. Utilizing a Flp-SUMO fusion protein, which functionally mimics naturally sumoylated Flp, we demonstrate that the modification signals ubiquitination of Flp, followed by its proteasome-mediated degradation. …”

Table_1_Effect of climate warming on the grain quality of early rice in a double-cropped rice field: A 3-year measurement.docx by Yong Wang (12837)

“…</p>Results<p>Compared with the control, FATI increased diurnal canopy temperature by 1.5°, and thus, rice growth duration was shortened by 4.0 d under warming. We found that warming significantly reduced both the milled rice and head rice rates relative to the control, thereby leading to a decrease in the milled rice and head rice yield by 3.9 and 8.3%, respectively. …”

Data_Sheet_1_A Monte Carlo Simulation Approach to Optimizing Capacity in a High-Volume Congenital Heart Pediatric Surgical Center.docx by Eleni G. Elia (12071126)

“…</p>Main Outcomes<p>Annual number of patient surgical cancellations and change in average daily census.</p>Results<p>We demonstrate that the models of strategic scheduling would result in up to 57% reduction in patient surgical cancellations, increase the historically low Monday census and decrease the historically higher late-mid-week (Wednesday and Thursday) censuses in our center.…”

Image_2_A Mutation in VWA1, Encoding von Willebrand Factor A Domain-Containing Protein 1, Is Associated With Hemifacial Microsomia.TIF by Yibei Wang (5321825)

“…</p>Results<p>Through WES and a set of filtration, we identified a c.G905A:p.R302Q point mutation in a novel candidate pathogenic gene, VWA1. …”

Image_1_A Mutation in VWA1, Encoding von Willebrand Factor A Domain-Containing Protein 1, Is Associated With Hemifacial Microsomia.TIF by Yibei Wang (5321825)

“…</p>Results<p>Through WES and a set of filtration, we identified a c.G905A:p.R302Q point mutation in a novel candidate pathogenic gene, VWA1. …”

DataSheet1_Bottom Drag Variations Under Waves and Currents: A Case Study on a Muddy Deposit off the Shandong Peninsula.DOCX by Fukang Qi (12985130)

“…In comparison, dramatically fewer such rule-of-thumb values are available for muddy beds. Here, we present results of variations in bottom drag as calculated from in situ measurements by bottom-mounted tripods that were placed across the top of a muddy deposit during two different deployments, one in summer and another in winter. …”

Supplementary Material for: Efficacy and Safety of a Persian Medicine Formula on Functional Dyspepsia Symptoms: A Randomized Double-blind Active-control Clinical Trial by Azimi M. (14520728)

“…The intra-group analysis showed a significant decrease in the symptoms severity and frequency at the end of week 4 in both groups (P<0.001). …”

Table_1_A Mutation in VWA1, Encoding von Willebrand Factor A Domain-Containing Protein 1, Is Associated With Hemifacial Microsomia.DOCX by Yibei Wang (5321825)

“…</p>Results<p>Through WES and a set of filtration, we identified a c.G905A:p.R302Q point mutation in a novel candidate pathogenic gene, VWA1. …”

Gene expression and metabolite profiling of gibberellin biosynthesis during induction of somatic embryogenesis in <i>Medicago truncatula</i> Gaertn by Rafał Igielski (4281487)

“…<div><p>Gibberellins (GAs) are involved in the regulation of numerous developmental processes in plants including zygotic embryogenesis, but their biosynthesis and role during somatic embryogenesis (SE) is mostly unknown. In this study we show that during three week- long induction phase, when cells of leaf explants from non-embryogenic genotype (M9) and embryogenic variant (M9-10a) were forming the callus, all the bioactive gibberellins from non-13-hydroxylation (GA₄, GA₇) and 13-hydroxylation (GA₁, GA₅, GA₃, GA₆) pathways were present, but the contents of only a few of them differed between the tested lines. …”

MicroRNA-32 promotes calcification in vascular smooth muscle cells: Implications as a novel marker for coronary artery calcification by Jianghua Liu (170107)

“…According to microarray analysis, we observed increased expression of miR-125b, miR-30a, and miR-32 and decreased expression of miR-29a, miR-210, and miR-320 during the progression of vascularcalcification. …”

Modelling the cost of interleaving with a “sluggish” task signal. by Timo Flesch (14475111)

“…We hypothesised that interleaved training would promote a solution as predicted by the linear model. …”