Reproductive Toxicity and Teratogenicity of Fluorene-9-bisphenol on Chinese Medaka (Oryzias sinensis): A Study from Laboratory to Field by Xiaolin Fan (1605136)

“…Toxico-transcriptome analyses showed that estrogen-responsive genes were significantly suppressed by BHPF, indicating that antagonist properties of BHPF on estrogen receptors might be causes for the decreased fecundity. Field investigations (Beijing) demonstrated that BHPF was detectable in 60% surface waters, with a mean concentration of 10.49 ± 6.33 ng/L, by gas chromatography–mass spectrometry, and similar effects in wild Chinese medaka were also observed, some of which the parameters were found to be obviously correlated with the BHPF levels in corresponding waters.…”

Reproductive Toxicity and Teratogenicity of Fluorene-9-bisphenol on Chinese Medaka (Oryzias sinensis): A Study from Laboratory to Field by Xiaolin Fan (1605136)

“…Toxico-transcriptome analyses showed that estrogen-responsive genes were significantly suppressed by BHPF, indicating that antagonist properties of BHPF on estrogen receptors might be causes for the decreased fecundity. Field investigations (Beijing) demonstrated that BHPF was detectable in 60% surface waters, with a mean concentration of 10.49 ± 6.33 ng/L, by gas chromatography–mass spectrometry, and similar effects in wild Chinese medaka were also observed, some of which the parameters were found to be obviously correlated with the BHPF levels in corresponding waters.…”

Magnitude of the different types of change for the seven considered MEMs forced with GFDL-SSP5-8.5. by Vianney Guibourd de Luzinais (16871842)

Spatial distribution of total consumer biomass response types, for the seven considered MEMs forced with GFDL-SSP5-8.5. by Vianney Guibourd de Luzinais (16871842)

Functioning summary of the 9 MEMs used in the study. by Vianney Guibourd de Luzinais (16871842)

Absence of RstA leads to a decrease in the number of origins per cell. by Yuan Yao (31223)

Spatial patterns of projected total consumer biomass relative changes in percent. by Vianney Guibourd de Luzinais (16871842)

S4 Fig - by Vianney Guibourd de Luzinais (16871842)

Fig 7 - by Vianney Guibourd de Luzinais (16871842)

Inhibition of HDAC6 activity decreased the phosphorylation of ERK1/2 and normalized the localization of EGFR from apical to basolateral. by Wei Liu (20030)

“…<p>(A) Knockdown HDAC6 with shRNA increases the degradation of EGFR and decreases the phosphorylation of ERK1/2. …”

NO donor dose dependently decreases cell number induced by PDGF-BB and blocks survivin expression and <i>in vitro</i>. by Jun Yu (5904)

“…<p>(A), Rat SMC were treated or not with PDGF (10 ng/ml), in the absence or presence of the NO donor, DETA/NO (10, 30, and 100 µM) and cell number quantified after 48 h. …”

Main outputs of the earth system models considered in the current study. by Vianney Guibourd de Luzinais (16871842)

Fig 1 - by Vianney Guibourd de Luzinais (16871842)

Evolution of R ratio (total consumer biomass change divided by NPP change) in regards to SST increase relative to reference period. by Vianney Guibourd de Luzinais (16871842)

S9 Fig - by Vianney Guibourd de Luzinais (16871842)

Ensemble projections of NPP and total consumer biomass changes, relative to 1995–2014, under SSP5-8.5 and for all the considered MEMs. by Vianney Guibourd de Luzinais (16871842)

The motor torque curves of load increase/decrease (A) the load of 10 N • m (B) the load of 20 N • m. by Taochang Li (20642935)

“…<p>The motor torque curves of load increase/decrease (A) the load of 10 N • m (B) the load of 20 N • m.…”

The motor speed curves of load increase/decrease (A) the load of 10 N • m (B) the load of 20 N • m. by Taochang Li (20642935)

“…<p>The motor speed curves of load increase/decrease (A) the load of 10 N • m (B) the load of 20 N • m.…”

Treatment with low doses of GI254023X causes a mild decrease in ADAM10 surface expression that correlates with a marked impairment of HCV infectivity. by Belén Carriquí-Madroñal (17396512)

siRNA knockdown of HDAC1 in virus producer cells results in decreased infectivity of HIV-1 in target cells. by Masha Sorin (263194)