A Case Study and Methodology for OpenSWATH Parameter Optimization Using the ProCan90 Data Set and 45 810 Computational Analysis Runs by Sean Peters (1490623)

“…For the compute poor parameter set, we find a 55% improvement in the run time from the default parameter set, at the expense of a 3.4% decrease in the number of quality protein identifications, and an intensity CV decrease from 14.0% to 13.7%.…”

Losartan does not decrease macrophage and MDSC infiltration. by Shanna A. Arnold (183991)

<i>S</i>. <i>aureus</i> binding activity to Seraph^® 100 during a prolonged treatment period. by Malin-Theres Seffer (14808772)

The oxygen level (kPa) for 50 and 100% habitat loss for each species and season under a doubling of atmospheric CO₂. by Emily Slesinger (6837740)

<i>WNT10A</i>^–/–KO skin wound showing reduced fibrosis/fibrogenesis associated with the decreased expression of stromagenesis-related genes. by Ke-Yong Wang (234594)

Decreased numbers of motor neurons in Tc1 and Dp(16)1Yey mice. by Sheona Watson-Scales (586942)

Delphinidin alters VEGF-A splicing to increase VEGF-A₁₆₅b and decrease total VEGF-A expression. by Megan Stevens (3964886)

“…<p><b>A)</b> Treatment of podocytes with delphinidin chloride (10 μg/ml) under normal glucose (NG; 5 mM glucose + 25 mM mannitol) and high glucose (HG; 30 mM glucose, 1 ng/ml TNFα, 1 ng/ml IL-6, and 100 nM insulin) for 48 hrs increased the protein expression of VEGF-A₁₆₅b relative to total VEGF-A₁₆₅ (quantified in <b>B</b>; *p<0.05 vs NG, †p<0.05 vs HG; n = 3 biological repeats; One-way ANOVA with Bonferroni post-hoc test for comparison between pairs; <b>A</b>—the same blot was first probed with VEGF-A₁₆₅b before stripping and reprobing with panVEGF-A). …”

Incubation of V79-CYP3A94/DD-POR cells with Shield-1 leads to a decrease of POR protein. by Ramona Dettwiler (664360)

Table 1_Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.xlsx by Chen Chen (6544)

“…Mechanistically, recombinant human S100A9 protein was found to induce a decrease in intracellular Ca²⁺ concentration, while AT-1 regulated the expression of tight junction proteins via modulation of the AMPK/mTOR signaling pathway. …”

Image 2_Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.tif by Chen Chen (6544)

“…Mechanistically, recombinant human S100A9 protein was found to induce a decrease in intracellular Ca²⁺ concentration, while AT-1 regulated the expression of tight junction proteins via modulation of the AMPK/mTOR signaling pathway. …”

Image 1_Atractylenolide-I restore intestinal barrier function by targeting the S100A9/AMPK/mTOR signaling pathway.tif by Chen Chen (6544)

“…Mechanistically, recombinant human S100A9 protein was found to induce a decrease in intracellular Ca²⁺ concentration, while AT-1 regulated the expression of tight junction proteins via modulation of the AMPK/mTOR signaling pathway. …”

Decreased production of IL-12p70 and IL-23 in response to LPS+R848 stimulation in frail old individuals. by Nathalie Compté (418458)

Posterior mean year-stage detection probabilities (red circles) and 95% Bayesian Credible Intervals (BCI; vertical black lines) of the (A) ≤100 m radius, and (B) infinite radius da... by Taza D. Schaming (8911517)

Diabetic wounds show increased amounts of vessel leakage and decreased pericyte coverage. by Uzoagu A. Okonkwo (8754933)

Model food web mean path length and dominant eigenvalue as a function of nominal size and connectance. by Jane Shevtsov (803549)

“…<p>Each boxplot shows the median, 75th and 25th percentiles for each data set, with whiskers extending up to 1.5 times the interquartile range and any points falling outside that area being plotted individually. In (a) and (c), mean path length generally decreases with connectance, while the dominant eigenvalue shows a curvilinear pattern. …”

S100A9: A Potential Biomarker for the Progression of Non-Alcoholic Fatty Liver Disease and the Diagnosis of Non-Alcoholic Steatohepatitis by Xiaolin Liu (403100)

“…We find that gene expression of s100a9 was higher in NAFL group compared with control, and was increased in NASH groups and decreased in NAFL + T2DM group compared with NAFL. …”

Microarray analysis of genes modulated by siRNA treatments. by Giorgia Urbinati (554921)

Effects of siRNA TMPRSS2-ERG on ERG protein expression and cell viability. by Giorgia Urbinati (554921)

“…The number of viable cells was measured and 100% cell viability corresponds to the number of living cells incubated only with transfecting agent. *** = <i>p</i><0.001, significant decrease compared to untreated cells or to siRNA Control (Kruskal & Wallis followed by Tukey and Dunnet test).…”

Susceptibility to COPD: Differential Proteomic Profiling after Acute Smoking by Lorenza Franciosi (600602)

“…SerpinB3 and Uteroglobin decreased after acute smoke exposure in young non-susceptible individuals exclusively, whereas Peroxiredoxin I, S100A9, S100A8, ALDH3A1 (Aldehyde dehydrogenase 3A1) decreased both in young susceptible and non-susceptible individuals, changes being significantly different between groups for Uteroglobin with iTRAQ and for Serpin B3 with iTRAQ and ELISA measures. …”

D452A, E464A, E470A, and E475A mutations decreased the calcium sensitivity. by Qinghuan Xiao (573411)