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point decrease » point increase (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search)
web decrease » we decrease (Expand Search), mean decrease (Expand Search), teer decrease (Expand Search)
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Frictional Effects on RNA Folding: Speed Limit and Kramers Turnover
Published 2018“…In the high-friction regime (η ≳ 10<sup>–5</sup> Pa·s), for both HP and PK, <i>k</i><sub>F</sub> values decrease as 1/η, whereas in the low friction regime, <i>k</i><sub>F</sub> values increase as η increases, leading to a maximum folding rate at a moderate viscosity (∼10<sup>–6</sup> Pa·s), which is the Kramers turnover. …”
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TRIM5 restriction of HIV-1 has decreased during evolution leading to humans.
Published 2013“…Original data is found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1000301#pbio.1000301-Goldschmidt1" target="_blank">[30]</a> and shows that the antiviral gene TRIM5 restricted HIV-1 better at points in evolution earlier than the chimp–human common ancestor than it does after that. …”
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FTY720 decreased viability, proliferation, and motility and induced apoptosis in human hepatoblastoma cells.
Published 2019“…(B) Following 24 hours of treatment with FTY720, the proliferation of HuH6 cells measured using the CellTiter 96 cell proliferation assay was significantly decreased (IC<sub>50</sub> = 6.4 μM, p ≤ 0.05). (C) HuH6 cells were plated and allowed to reach 80% confluence, at which time the media was changed for fresh media (0, 5, or 8 μM FTY720) and a standard scratch wound was made. …”
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Netrin-1 overexpression increases HCV RNA and specific infectivity of HCV virions in vitro whereas Netrin-1 depletion decreases HCV RNA and specific infectivity in vitro.
Published 2016“…Netrin-1 depletion impedes HCV. Huh7.5 cells were transfected with siRNAs, infected at a MOI of 0.1 24 h after seeding, and trypsinized at day five post-infection before a second siRNA transfection. …”
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