Image_4_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Image_3_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Image_8_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Image_6_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Image_9_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Image_7_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Image_2_In Vitro Characterization of 177Lu-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer.ti... by Tabassom Mohajershojai (9441050)

“…Moreover, the heat shock protein 90 inhibitor onalespib has previously demonstrated radiotherapy potentiation effects in vivo. In the present study, a ¹⁷⁷Lu-radiolabeled anti-CEA hT84.66-M5A mAb (M5A) conjugate was developed and the potential therapeutic effects of ¹⁷⁷Lu-DOTA-M5A and/or onalespib were investigated. …”

Source data for Fig 5. by Peiqi Yin (6533747)

Potential miRNAs targeting PDE8A. by Thijs Booiman (185008)

“…#<p>Fold change in expression in which day 5 is compared to day 0; >1 is an increase and <1 is a decrease in expression.…”

H₂O₂-induced mitochondrial size decrease is prevented by WY pre-treatment in hippocampal neurons. by Juan M. Zolezzi (586604)

The pro-inflammatory cytokines were mainly inhibited but anti-inflammatory genes were significantly activated in zebrafish embryos under PGRP5-KD conditions. by Xi Li (19208)

The mole fraction of arsenic acid (H₃As(V)O₄) species at pH 3.90 and pH 7.96, the minimum and maximum pH values observed in this study (Fig 8; Table 1) [23]. by Seth H. Frisbie (7821866)

The expression of Cregs is diminished in the allograft model with the progression of ATCMR. by Kazuaki Yamanaka (2541484)

“…Statistical significance was assessed by the t-test and Tukey’s HSD test. (A) qRT-PCR showed significantly diminished expression levels of Crry and CD59 mRNA in the allografts, compared to syngeneic grafts, at day 5 after transplantation. …”

Spatiotemporal Trends Spanning Three Decades Show Toxic Levels of Chemical Contaminants in Marine Mammals by Rosie S. Williams (17343531)

“…We find that although levels of pollutants have decreased overall, there is significant spatial and taxonomic heterogeneity such that pollutants remain a threat to biodiversity in several species and regions. …”

Exposure to Contemporary and Emerging Chemicals in Commerce among Pregnant Women in the United States: The Environmental influences on Child Health Outcome (ECHO) Program by Jessie P. Buckley (12525195)

“…Concentrations of certain chemicals decreased with the calendar year, whereas concentrations of their replacements increased. …”

A therapeutic epitopes-based vaccine engineering against <i>Salmonella enterica</i> XDR strains for typhoid fever: a Pan-vaccinomics approach by Kanwal Khan (12069482)

Electron micrographs (magnification of × 30,000) and polyP levels (AU, arbitrary units) of <i>L</i>. <i>rhamnosus</i> CRL 1505. by María A. Correa Deza (4097602)

A Wearable, Humidity-Resistant Triboelectric Nanogenerator Based on Hydrophobic Leather for Human Motion Monitoring and Sign Language Recognition by Rui Sun (177521)

“…The WPL-TENG maintained a stable output voltage of ∼57 V across −10 to 98 °C, with only a 2% decrease in output voltage when humidity increased from 28% to 86%. …”

A Wearable, Humidity-Resistant Triboelectric Nanogenerator Based on Hydrophobic Leather for Human Motion Monitoring and Sign Language Recognition by Rui Sun (177521)

“…The WPL-TENG maintained a stable output voltage of ∼57 V across −10 to 98 °C, with only a 2% decrease in output voltage when humidity increased from 28% to 86%. …”

Comparison between fitted model (solid lines) and data (markers) at the whole lung scale (a) and in the same three example grids as Fig 2b. by Monica E. Shapiro (22622240)