Data_Sheet_1_rdHSV-CA8 non-opioid analgesic gene therapy decreases somatosensory neuronal excitability by activating Kv7 voltage-gated potassium channels.docx by Munal B. Kandel (18526539)

“…This study tested the hypothesis that novel JDNI8 replication-defective herpes simplex-1 viral vectors (rdHSV) carrying a CA8 transgene (vHCA8) reduce primary afferent neuronal excitability. …”

Table_1_Decreased circulating dipeptidyl peptidase-4 activity after short-term intensive insulin therapy predicts clinical outcomes in patients with newly diagnosed type 2 diabetes... by Jie Chen (5892)

“…After three months post-SIIT, DPP-4 activity remained stable in the remission group (39.63 ± 8.53 nmol/L) but increased in the non-remission group (42.34 ± 6.64 nmol/L). This resulted in a more pronounced decrease in DPP-4 activity from baseline in the remission group (-3.39 ± 8.90 vs. -1.10 ± 8.95, P = 0.035). …”

Transitioning of people with T1D from Multiple Daily Injections (MDI) and Self-Monitoring of Blood Glucose (BGM) directly to MiniMed™ 780G Advanced Hybrid Closed Loop (AHCL) system... by Bartłomiej Matejko (13180606)

“…</p> <p>Results: 41 participants were recruited and randomized to either the AHCL (20) or the MDI+BGM (21) group. 37 participants (age 40.3±8.0 years; duration of diabetes 17.3 ± 12.1 years; BMI 25.1±3.1 kg/m2; HbA1c 7.2% ± 1.0) completed the study. Time spent in target (TIR) increased from 69.3±12.3% at baseline to 85.0±6.3% at 3 months in the AHCL group, while remaining unchanged in the control group: treatment effect 21.5% [95% CI 15.7, 27.3%]; p < 0.001. …”

Data_Sheet_1_Mental Health in German Paralympic Athletes During the 1st Year of the COVID-19 Pandemic Compared to a General Population Sample.docx by Aglaja Busch (9922233)

“…In para-athletes, no significant and a weak positive correlation was found between decreased training load and PHQ-4 values and a stress level, respectively. …”

Point cell model behavior. by Evan Cudone (5768813)

After the injection of PAM, the level of PPARγ increases, and the expression of TGFβ1/SMAD3 decreases, thereby inhibiting EMT and improving intestinal fibrosis. (A) Changes in the mRNA expression level of E-cadherin. (B) Changes in the mRNA expression level of N-cadherin. (C) Changes in the mRNA expression level of V-cadherin. (D) Changes in the mRNA expression level of COL1A1.... by Yi You (2567890)

“…(C) Changes in the mRNA expression level of V-cadherin. (D) Changes in the mRNA expression level of COL1A1. …”

IL-1Ra ASO treatment in HFD-fed obese mice results in decreased body weight (A) despite similar food intake (B) (food intake measured weekly and presented as average food intake ov... by Niclas Franck (632562)

The association between observed mobility and quality of life in the near elderly by Jason Shafrin (4379500)

“…Diseases that decrease mobility, such as arthritis, are likely to have a significant impact on quality of life.…”

Supplementary Material for: Downregulation of N-Acetylglucosaminyltransferase GCNT3 by miR-302b-3p Decreases Non-Small Cell Lung Cancer (NSCLC) Cell Proliferation, Migration and In... by Li Q. (2850350)

Mean left and right hemisphere <i>µ</i> time-frequency ERSPs (event-related spectral perturbations). by Andrew Bowers (449266)

“…Non-significant values are colored green, with significant values shown in orange and red. Event-related decreases in spectral power are indicated in blue (−4.5) and increases are indicated in red (4.5).…”

Immunofluorescence staining patterns for 5-mC and 5-hmC in CIN3 lesions with overlying columnar epithelium, showing extensive heterogeneity for methylation and hydroxymethylation. by Jobran M. Moshi (18405149)

“…In <b>C</b> and <b>E</b> +: indicates areas with an increased 5-hmC immunostaining as compared to * indicating areas with a decrease of 5-hmC immunostaining.…”

Flow diagram of participant selection. by Prajwal Paudel (7359209)

“…Lack of exposure to ACS was associated with higher odds of prolonged hospital stay (aOR: 3.321, 95% CI: 1.957–5.638) and mortality (aOR: 5.731, 95% CI: 3.199–10.266).…”

Supplementary file ACS. by Prajwal Paudel (7359209)

“…Lack of exposure to ACS was associated with higher odds of prolonged hospital stay (aOR: 3.321, 95% CI: 1.957–5.638) and mortality (aOR: 5.731, 95% CI: 3.199–10.266).…”

Muscle differentiation genes are regulated by laminin α5 chain. by Léa Ritié (161318)

“…<p>(A) Semi-quantitative RT-PCR experiments were performed on E15.5 control and knockout intestines for genes belonging to the muscle compartment. …”

Decreasing <i>VCP</i> function increases the activation of the Ire1/Xbp1 UPR pathway in <i>Rh1^P37H</i>-expressing flies. by Ana Griciuc (243073)

Personality traits in people with multiple sclerosis: A systematic review and meta-analysis by Omid Mirmosayyeb (12431770)

“…<p><b>Objective:</b> Although numerous studies have investigated personality traits in people with multiple sclerosis (PwMS), a thorough systematic review and meta-analysis of this evidence has not been conducted. …”

Dataset_Plos_weighting_def - by Jesús Martín-Fernández (406234)

“…The probability of reporting a “very good” health condition decreased with a diagnosis of hypertension (6.2%; CI 95%: 3.1–9.3%) and hypertensive medication (4.5%; CI 95%: 1.8–7.3%). …”

The effects of ox-LDL and propionate on HCMECs apoptosis. by Dan Hong (731836)

Targeting of Alpha-V Integrins Reduces Malignancy of Bladder Carcinoma by Geertje van der Horst (458926)

“…<div><p>Low survival rates of metastatic cancers emphasize the need for a drug that can prevent and/or treat metastatic cancer. αv integrins are involved in essential processes for tumor growth and metastasis and targeting of αv integrins has been shown to decrease angiogenesis, tumor growth and metastasis. …”

Supplemental Figure S2 from Evolutionary Action Score of <i>TP53</i> Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and... by David M. Neskey (14920268)