Image1_Circ-CDK8 regulates SLC7A11-mediated ferroptosis by inhibiting miR-615-5p to promote progression in oral squamous cell carcinomas.TIF by Kai Sun (140584)

“…Bioinformatics analyses and luciferase reporter assays were performed and revealed targeted relationships between circ-CDK8 and miR-615-5p, miR-615-5p and SLC7A11. Interference with circ-CDK8 expression reduced SLC7A11 expression by sponging miR-615-5p, suppressed OSCC cell migration and invasion, and promoted ferroptosis by increasing ROS, MDA, and iron levels and decreasing GSH and GPX4 levels in OSCC cells. …”

Table1_Circ-CDK8 regulates SLC7A11-mediated ferroptosis by inhibiting miR-615-5p to promote progression in oral squamous cell carcinomas.DOCX by Kai Sun (140584)

“…Bioinformatics analyses and luciferase reporter assays were performed and revealed targeted relationships between circ-CDK8 and miR-615-5p, miR-615-5p and SLC7A11. Interference with circ-CDK8 expression reduced SLC7A11 expression by sponging miR-615-5p, suppressed OSCC cell migration and invasion, and promoted ferroptosis by increasing ROS, MDA, and iron levels and decreasing GSH and GPX4 levels in OSCC cells. …”

Image2_Circ-CDK8 regulates SLC7A11-mediated ferroptosis by inhibiting miR-615-5p to promote progression in oral squamous cell carcinomas.TIF by Kai Sun (140584)

“…Bioinformatics analyses and luciferase reporter assays were performed and revealed targeted relationships between circ-CDK8 and miR-615-5p, miR-615-5p and SLC7A11. Interference with circ-CDK8 expression reduced SLC7A11 expression by sponging miR-615-5p, suppressed OSCC cell migration and invasion, and promoted ferroptosis by increasing ROS, MDA, and iron levels and decreasing GSH and GPX4 levels in OSCC cells. …”

Bar chart and logistic regression curve of yearly positive <i>S</i>. <i>stercoralis</i> results (both charcoal culture and IgG ELISA), in Nepalese Gurkha recruits who migrated to t... by William D. Nevin (17854751)

Cumulative percentage of positive diagnoses made by light microscopy following FEA concentration, depending on whether one, two or three stool samples were analysed, in Nepalese Gu... by William D. Nevin (17854751)

General laboratory tests and specific coagulation test in PCR SARS-CoV-2 positive patients with and without thrombosis. by B. de Laat (12475632)

Cell cycle progression is altered in DCT knockdown cells compared to control cells. by Pınar Aksoy (3663211)

<i>Gria1</i> and <i>Grin1</i> mRNA expressions in POMC neurons is impaired by the lack of <i>Efnb1</i> in POMC-expressing progenitors. by Manon Gervais (9708032)

Bar chart and logistic regression curve of yearly prevalence of hookworm infection in Nepalese Gurkha recruits who migrated to the UK 2012–2020. by William D. Nevin (17854751)

Bar chart and logistic regression curve of yearly prevalence of <i>T</i>. <i>trichiura</i> ova detection in Nepalese Gurkha recruits who have migrated to the UK 2012–2021. by William D. Nevin (17854751)

Depleting extracellular ATP reverts the mesenchymal phenotype of ovarian carcinoma cell lines. by José David Nuñez-Ríos (18823719)

DataSheet1_MircroRNA Let-7a-5p in Airway Smooth Muscle Cells is Most Responsive to High Stretch in Association With Cell Mechanics Modulation.zip by Kang Wen (7186409)

“…Direct binding between let-7a-5p and ItgαV was also verified in classical model cell line by using dual-luciferase assays.…”

Percentage of rewards obtained (A-F), call rate (GH), and session duration (IJ) in rats grouped by performance in USV-training. by Agnieszka D. Wardak (17941139)

Table 2_A comprehensive and systematic review on resveratrol supplementation as a promising candidate for the retinal disease: a focus on mechanisms of action from preclinical stud... by Xiao-Min Lv (21575681)

“…Moreover, a decrease in malondialdehyde (SMD = −9.29,95% Cl = [−12.84, −5.74], p < 0.00001), reactive oxygen species level (SMD = −4.29,95% Cl = [-6.25, −2.32], p < 0.0001), cyclooxygenase-2 (SMD = −2.66, 95% Cl = [−4.01, −1.30], p =0.0001), tumour necrosis factor-α(SMD = −3.96,95% Cl = [−6.27, −1.65], p = 0.0008) and interleukin-6 (SMD = −3.32,95% Cl = [−4.20, −2.44], p < 0.00001) was observed. …”

Table 1_A comprehensive and systematic review on resveratrol supplementation as a promising candidate for the retinal disease: a focus on mechanisms of action from preclinical stud... by Xiao-Min Lv (21575681)

“…Moreover, a decrease in malondialdehyde (SMD = −9.29,95% Cl = [−12.84, −5.74], p < 0.00001), reactive oxygen species level (SMD = −4.29,95% Cl = [-6.25, −2.32], p < 0.0001), cyclooxygenase-2 (SMD = −2.66, 95% Cl = [−4.01, −1.30], p =0.0001), tumour necrosis factor-α(SMD = −3.96,95% Cl = [−6.27, −1.65], p = 0.0008) and interleukin-6 (SMD = −3.32,95% Cl = [−4.20, −2.44], p < 0.00001) was observed. …”

Table5_Causal relationship between physical activity and platelet traits: a Mendelian randomization study.XLSX by Mingyuan Jia (13117449)

Effects of drug treatments on culture cells and embryos. by Xiaowen Jiang (8291814)

Number of Nepalese Gurkha recruits arriving in the UK and undergoing screening for GIP, each year from 2012–2020. by William D. Nevin (17854751)

Combustion Characteristics of C₅ Alcohols and a Skeletal Mechanism for Homogeneous Charge Compression Ignition Combustion Simulation by Sungwoo Park (1234614)

“…C₅ alcohol blending in PRF75 in HCCI combustion leads to a significant decrease of low-temperature heat release (LTHR) and a delay of the main combustion. …”

Combustion Characteristics of C₅ Alcohols and a Skeletal Mechanism for Homogeneous Charge Compression Ignition Combustion Simulation by Sungwoo Park (1234614)

“…C₅ alcohol blending in PRF75 in HCCI combustion leads to a significant decrease of low-temperature heat release (LTHR) and a delay of the main combustion. …”