Table 5_Therapeutic potential of five frequently prescribed herbs in obesity-associated Hashimoto’s thyroiditis: insights from efferocytosis regulation.xlsx by Jiahao Zhou (11385383)

“…Moreover, TCM offers significant benefits in regulating lipid metabolism and decreasing systemic inflammation.</p>Methods<p>Targets of five high-frequency herbs (Hedysarum multijugum Maxim, Radix Bupleuri, Prunella vulgaris, Fritillaria thunbergii Bulbus, and Angelicae sinensis Radix) were obtained from the TCMSP and Swiss Target Prediction databases. …”

Increased ER stress in the <i>ColIITg^cog</i> mouse. by Louise H. W. Kung (693522)

Table_5_Integrative Analysis of LGR5/6 Gene Variants, Gut Microbiota Composition and Osteoporosis Risk in Elderly Population.DOCX by Dong-sheng Di (11634688)

“…The rs10920362 CT/TT genotype associated with a decreased relative abundance of Actinobacteria (β = −1.32, P < 0.001), Bifidobacteriaceae (β = −1.70, P < 0.001), and Bifidobacterium (β = −1.70, P < 0.001) compared to the CC genotype.…”

TRPM7 regulates intracellular Ca²⁺ and Mg²⁺ concentration of cortical astrocytes. by Zhao Zeng (478844)

“…However, knockdown of TRPM7 in mouse cortical astrocytes significantly decreases intracellular Mg²⁺ by 43.5% ± 9.8% (*, <i>p</i> < 0.05, n = 4). …”

Finite mixture model with a beta-binomial distribution of errors exploring the effect of duration of symptoms, incubation period and whether pathogens induce a local or a systemic... by Gabriele Sorci (288219)

Ontogeny of the B- and T-cell response in a primary Zika virus infection of a dengue-naïve individual during the 2016 outbreak in Miami, FL by Michael J. Ricciardi (4102375)

“…We collected blood from a female with a maculopapular rash at day (D) 5 and D7 post onset of symptoms (POS) and we continued weekly blood draws out to D148 POS. …”

Silencing TRPM7 in Mouse Cortical Astrocytes Impairs Cell Proliferation and Migration via ERK and JNK Signaling Pathways by Zhao Zeng (478844)

“…Knocking down TRPM7 with specific siRNA impairs the proliferation and migration of astrocytes by 40.2% ± 3.9% and 40.1% ± 11.5%, respectively. Consistently, inhibition of TRPM7 with 2-aminoethoxydiphenyl borate (2-APB) also decreases astrocyte proliferation and migration by 46.1% ± 2.5% and 64.2% ± 2.4%. …”

Conditional <i>Cdk5rap2</i> KO mouse and novel <i>mCdk5rap2</i> splice variants. by Nadine Kraemer (790327)

“…(D) Identification of a novel <i>mCdk5rap2</i> splice variant (<i>mCdk5rap2-V1</i>) through gel electrophoresis and sequencing of PCR products from exon 2 to exon 7 of WT and hom KO cDNA. …”

Effects of the unilateral submaximal eccentric exercise on knee flexor’s of neuromuscular function and perceived muscle soreness (PMS) of both the EL (exercised limb) and the NEL (... by Jennifer Gioda (17951785)

Supplemental Video V3: Change in perfusion in PAH by Tilo Winkler (6288935)

“…Supplemental Video V3: Spatial distribution and magnitude of changes in perfusion in a subject with PAH in response to the administration of O₂+iNO. …”

Genetic analysis of <i>OBSCN</i> c.13330 C>T and <i>FLNC</i> c.5161delG mutations. by Daniela Rossi (1716643)

Stem Cell-Derived, microRNA-Carrying Extracellular Vesicles: A Novel Approach to Interfering with Mesangial Cell Collagen Production in a Hyperglycaemic Setting by Sara Gallo (3111309)

“…This resulted in STAT5 down-regulation and a decrease in miR-21 content, TGFβ expression and matrix protein synthesis within MCs. …”

Interactomes of HMR/LHR interactors provide evidence for the existence of a defined HMR protein complex (related to Fig 1). by Andrea Lukacs (3752956)

Noise pollution limits metal bioaccumulation and growth rate in a filter feeder, the Pacific oyster <i>Magallana gigas</i> by Mohcine Charifi (4535101)

“…This latter conclusion points towards a potential risk in terms of ecosystem productivity.…”

SHOULD MALE CIRCUMCISION BE PROMOTED IN DEVELOPING COUNTRIES AS MAJOR MEANS OF HIV PREVENTION by Wazhma Hakimi.pdf by Wazhma Hakimi (8820506)

“…However, male circumcision (MC) has been known as a religious or traditional ritual, it was suggested as a mean for prevention of sexually transmitted infections (STIs) in 1850s. …”

Synonymous Rare Arginine Codons and tRNA Abundance Affect Protein Production and Quality of TEV Protease Variant by Jie Fang (306330)

“…<div><p>It has been identified that a TEV protease (TEVp) variant, TEVp^5M, displays improved solubility. …”

Image_5_Projected Effects of Climate-Induced Changes in Hydrodynamics on the Biogeochemistry of the Mediterranean Sea Under the RCP 8.5 Regional Climate Scenario.jpg by Rémi Pagès (5142440)

“…In forecast studies based on a RCP 8.5 scenario, there seems to be a consensus that, along with an increase in temperature and salinity over the next century, a reduction in the intensity of deep-water formation and a shallowing of the mixed layer [especially in the North-Western Mediterranean Sea (MS)] are expected. …”

microRNA-34a-Mediated Down-Regulation of the Microglial-Enriched Triggering Receptor and Phagocytosis-Sensor TREM2 in Age-Related Macular Degeneration - Fig 6 by Surjyadipta Bhattacharjee (3181674)

“…After vacuum evaporation of HFIP, aliquoted peptide was re-suspended with DMSO to 5 mM and diluted to 5 μM into the cell culture media; <b>(B)</b> cells were treated with a scrambled miRNA-34a sequence (miRNA-34a-<b>sc</b>; 30 nM;, control, <b>a-d</b>, middle row); or <b>(C)</b> with an LNA-stabilized miRNA-34a (30 nM; miRNA-34a stressed; <b>a-d</b>; bottom row); treatments were for 24 hr before incubation with 5 uM of Aβ42 (made up as in [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref033" target="_blank">33</a>]) for another 24 hr before assay; MG cells were subsequently stained using a murine amyloid beta MABN10 (red fluorescence λ_max~650 nm; anti-Aβ antibody, clone W0-2; Millipore, Bellerica MA), a TREM-2 antibody (M-227): sc-48765 (green fluorescence; λ_max~510 nm; Santa Cruz, Santa Cruz CA) or DAPI nuclear stain (blue fluorescence; λ_max~470 nm) as in <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.g003" target="_blank">Fig 3</a>;</b> arrows indicate Aβ42 uptake into MG cells; note decreased presence of TREM2 in miRNA-34a treated MG cells (bottom row, panel B) and decrease in ingested Aβ42 peptide within C8B4 cells (<b>C</b>; bottom row, panel <b>d</b>). …”

Changes after 45 minutes in the proportion of LTP, LTD or no plasticity responses observed in L5PyNs population induced by the HFS protocol in the presence of D1R agonist or antago... by Claire Nicole Jeanne Meunier (703124)

“…<p>(A and D) Percentages of L5PyNs displaying LTP, LTD or no plasticity in 129/Sv mice and 5-HT_1AR-KO mice in control conditions. …”

All-Atom Simulations Reveal the Effect of Membrane Composition on the Signaling of the NKG2A/CD94/HLA‑E Immune Receptor Complex by Martin Ljubič (15680161)

“…Our results reveal significant variations in the behavior of the immune complex structure across five different membrane compositions, which include POPC, POPA, DPPC, and DLPC phospholipids, and a mixed POPC/cholesterol system. …”