Time Course Analysis of Skeletal Muscle Pathology of GDE5 Transgenic Mouse by Takao Hashimoto (662481)

“…We have previously generated that a truncated mutant of GDE5 (GDE5dC471) that lacks phosphodiesterase activity and shown that transgenic mice overexpressing GDE5dC471 in skeletal muscles show less skeletal muscle mass than control mice. …”

TTBK2 homodimerizes through its C-terminus. by Emily Bowie (543704)

Risk and safety profile in checkpoint inhibitors on non-small-cell lung cancer: A systematic review by Sara Maria Majernikova (13231062)

“…<p>Treating non-small-cell lung cancer (NSCLC) has gained increased importance in recent years due to the high mortality rate and dismal five-year survival rate. Immune checkpoint inhibitors (ICI) are a promising approach with exceptional outcomes in NSCLC thanks to the antigenic nature of cells. …”

(a) Molds; (b) Samples; (c)(d) Test devices. by Chenhao Li (822769)

“…SHMP interacted with Ca²⁺, significantly influencing the cement hydration; notably, 1% content resulted a notable reduction of samples from 167.5 kPa to 21.5 kPa at 1 day. …”

Identification of +TIPs required for MT plus-end targeting of dynein-dynactin in the <i>C</i>. <i>elegans</i> early embryo. by Daniel J. Barbosa (4288462)

“…Images correspond to maximum intensity projections over time (12 frames acquired every 5 s). Scale bar, 5 μm; insets, 2 μm. <b>(C)</b> Cortical confocal section in one-cell embryos co-expressing GFP::p50^DNC-2 and EBP-2::mKate2, showing that depletion of dynein intermediate chain^DYCI-1 or LIS-1 decreases dynactin levels at MT plus ends. …”

Length-Dependent Convergence and Saturation Behavior of Electrochemical, Linear Optical, Quadratic Nonlinear Optical, and Cubic Nonlinear Optical Properties of Dipolar Alkynylruthe... by Bandar Babgi (2360545)

“…The syntheses of <i>trans</i>-[Ru{4,4′-CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppm)₂] (<b>19</b>), <i>trans</i>-[Ru{4,4′,4′′-CCC₆H₄CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppm)₂] (<b>20</b>), <i>trans</i>-[Ru{4,4′,4′′,4′′′-CCC₆H₄CCC₆H₂[2,5-(OEt)₂]CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppe)₂] (<b>21</b>), <i>trans</i>-[Ru{4,4′,4′′,4′′′-CCC₆H₄CCC₆H₂[2,5-(OEt)₂]CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppm)₂] (<b>22</b>), <i>trans</i>-[Ru{4,4′,4′′,4′′′-CCC₆H₄CCC₆H₄CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppm)₂] (<b>23</b>), and <i>trans</i>-[Ru{4,4′,4′′,4′′′,4′′′′-CCC₆H₄CCC₆H₄CCC₆H₂[2,5-(OEt)₂]CCC₆H₂[2,5-(OEt)₂]CCC₆H₄NO₂}Cl(dppm)₂] (<b>24</b>) are reported, together with those of precursor alkynes, complexes with the donor−π-bridge−acceptor formulation that affords efficient quadratic and cubic NLO compounds; the identity of <b>19</b> was confirmed by a structural study. …”

TRIM5α induces an antiviral state following infection with restricted viruses. by Natacha Merindol (3521828)

“…The total percentage of GFP⁺ cells is shown in bold. <b>(b)</b> Fold decreases in NRC1_GFP (n = 25) and NRC10_GFP (n = 17) infectivity in T5KO and control (CAG) Jurkat cells subjected to a first infection with isolates-derived DsRed-vectors. …”

The percentage of cells with protein aggregates cotransfected with αA- and αB-crystallin or R120G αB-crystallin (αBM) genes by Bing-Fen Liu (81305)

“…</p><p></p> The x-axis labels are either RED-αB- or the pairs of GFP-αA- and RED-αB-crystallin. A four-fold decrease of cells with protein aggregates was observed for cotransfection of αA- and αB-crystallin (the asterisk indicates a p=0.006), but only about a 1.5 fold decrease for cotransfection of αA- and αBM-crystallin (the double asterisk indicates a p=0.02). …”

S1 Dataset - by Mengnan Lu (12128694)

“…This was confirmed by univariate analysis of the top five metabolic pathways. Based on the analysis of soil and metabolomics, it was found that soil water content was also a factor affecting <i>E</i>. …”

FIGURE 5 from Proteasome Inhibition Reprograms Chromatin Landscape in Breast Cancer by H. Karimi Kinyamu (18387319)

“…Each row corresponds to a DOCR, and they are split by increase (<b>GAIN</b>) or decrease (<b>LOST</b>) in accessibility and by genomic category (<b>PROMOTER</b>, <b>GENIC</b>, <b>INTERGENIC</b>). …”

Hypoxia upregulates ALKBH5 <i>via</i> HIF-1α. by Armin Thalhammer (233088)

“…RT-Q-PCR analysis (<b>iv</b>) shows a significant (p<0.01) increase in <i>ALKBH5</i> mRNA after doxycycline administration. …”

Image_5_Prostate cancer epidemiology and prognostic factors in the United States.tif by Saimaitikari Abudoubari (16893914)

“…Among the different age groups, the incidence rate was significantly increased in 15-54 and 55-64 age groups with AAPC of 4.03 (95% CI:2.73~5.34) and 2.50 (95% CI:0.96~4.05), respectively, and significantly decreased in ≥85 age group with AAPC of -2.50 (95% CI:-3.43~-1.57). …”

Select genes are co-regulated by NSL and RbBP5-MLL complexes. by Xiaoming Zhao (484793)

“…<p><b>A.</b> Alteration of global histone H4 or H3K4 modifications in hMOF, hNSL1, hRbBP5 or hMSL3L1 siRNA knockdown HeLa cells. …”

Knock-out of <i>atp6v1e1b</i> in zebrafish shows an early phenotypic read-out. by Lore Pottie (10994479)

“…<p>(A) Schematic representation of the <i>atp6v1e1b</i> gene (transcript ENSDAR00000050221.5). …”

The C-terminal tyrosine of α-tubulin is required for centration/rotation of the nucleus-centrosome complex but not for MT tip tracking of dynactin. by Daniel J. Barbosa (4288462)

“…****<i>P</i> < 0.0001; **<i>P</i> < 0.01; ns = not significant, <i>P</i> > 0.05. Scale bar, 5 μm. <b>(I)</b> <i>(left)</i> Cortical confocal section of a control and <i>tba-1/2(YA/YA)</i> one-cell embryo in metaphase expressing GFP::p50^DNC-2. …”

Table_1_100% Fruit Juice and Dental Health: A Systematic Review of the Literature.docx by DeAnn Liska (6948188)

“…</p><p>Methods: We performed a systematic search in MEDLINE/PubMed, EMBASE, and Web of Science for studies published from inception through May 2018, and the Cochrane Library databases for reports published through January 2018. …”

Rapid degeneration of 5-HT neurons in SERT-Cre^cre/wt Munc18-1^lox/lox mice. by Jacobus J. Dudok (338648)

“…(O) Analysis of the number of 5-HT cell bodies in the sections showed that there is no difference at E16, but at E18 and P2 there is a decrease of 80% to 90% in the number of 5-HT cell bodies in SERT-Cre^cre/wt Munc18-1^lox/lox sections. …”

Cutaneous HPV5 E7 protein reduces pocket proteins levels. by Águeda Buitrago-Pérez (149456)

“…Transfection efficiencies were assesed using pcDNA-eGFP. Note that both 5E7 and 16E7, but not 10E7, induced a significant decrease in transiently expressed pRb protein. …”

The relationship between <i>A</i>_<i>w</i> and human feelings. by Ying Zhao (16546)

“…<div><p>During the field operation of rice combine harvester, the vibration generated by vibration component will only reduce mechanical reliability and yield, but also cause resonance in the human body, leading to a decrease in driving comfort and even damage to the driver’s health. …”

Hazard Ratios (HRs) and 95% CI for cancer per tertile decrease in DII, and tertile increase in MDS, at baseline in all participants (n = 100,881), men (n = 49,880), and women (n =... by Stina Bodén (3905218)