Suitability of Porcine Chondrocyte Micromass Culture To Model Osteoarthritis in Vitro by Niels Schlichting (1783198)

“…Expression of genes related to cartilage ECM formation (<i>COL2A1</i>, <i>COL9A1</i>, <i>COMP</i>, <i>aggrecan</i>) as well as hypertrophic bone formation (<i>COL1A1</i>, <i>COL10A1</i>) was predominantly found decreased. …”

Suitability of Porcine Chondrocyte Micromass Culture To Model Osteoarthritis in Vitro by Niels Schlichting (1783198)

“…Expression of genes related to cartilage ECM formation (<i>COL2A1</i>, <i>COL9A1</i>, <i>COMP</i>, <i>aggrecan</i>) as well as hypertrophic bone formation (<i>COL1A1</i>, <i>COL10A1</i>) was predominantly found decreased. …”

The relative change in incident cases of RA among AYAs between 1990 and 2019. by Ruibo Li (2063167)

Global map of 2019 incidence of RA among AYAs. by Ruibo Li (2063167)

Spike triggered analysis of direction selective simple and complex V1 cells. by Timm Lochmann (390227)

“…The grayscale value represents the magnitude of the STRF, indicating how strongly an increased/decreased luminance value at a spatiotemporal location increases or decreases the probability to spike. …”

<em>Alu</em> Sequences in Undifferentiated Human Embryonic Stem Cells Display High Levels of A-to-I RNA Editing by Sivan Osenberg (145941)

“…We identified high editing levels of <em>Alu</em> repetitive elements in hESCs and demonstrated a global decrease in editing levels of non-coding <em>Alu</em> sites when hESCs are differentiating, particularly into the neural lineage. …”

Compound 390 induces HBV capsid accumulation via an ROS-mediated mechanism. by Daniel P. Bradley (10306893)

BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell by Jude T. Deeney (335344)

SARS-CoV-2 antibody responses are sustained and are predominantly focused on Spike. by Fiona Tea (2502700)

“…<b>(D)</b> 54%–57% (gray) of sera were Membrane IgG+, and most ADAPT had stable levels, whereas a larger proportion of LIFE had decreasing levels. …”

The <i>rdm16</i> mutation reduced the levels of Pol V transcripts. by Chao-Feng Huang (457657)

“…<p>(<b>A–E</b>) Five Pol V-dependent loci showed decreased Pol V transcript levels in <i>rdm16ros1</i> compared to WT and <i>ros1</i> controls. …”

Impact of haemostasis methods during ovarian cystectomy on ovarian reserve: a pairwise and network meta-analysis by Qin Xie (93388)

“…A traditional meta-analysis was performed using Review Manager software. …”

Voltage-activated potassium (K_v) currents in differentiated cells. by Grit Schaarschmidt (262249)

“…I_K significantly increased, while I_A decreased in differentiated cells compared to hNPCs (unpaired t-test, *p<0.05, **p<0.01).…”

Table5_The Pharmacological Mechanism of Guchangzhixie Capsule Against Experimental Colitis.DOCX by Jing Yan (312090)

“…However, the underlying molecular mechanisms have not been elucidated. In the present study, a murine model of experimental colitis was established by orally feeding 4% dextran sodium sulfate (DSS) for 5 days and subsequently subjecting to GCZX treatment for another 15 days. …”

Comparison of time course of the SARS-CoV-2 pandemic up to 7 November 2020 for the seven regions in England for the time-varying IFR model, given <i>δ</i>_<i>p</i> as 2 w... by Siyu Chen (278663)

(A, B) Western blot analysis of lysates from the two clones with the TrkB-BAC minigene (77−5 and 77−6) before and after deglycosylation and probed with an antibody recognizing TrkB... by Francesco Tomassoni-Ardori (22216521)

Proposed model for the signaling pathway by which high glucose participates in the GEnCs injury via the RXRα/circ8411/miR-23a-5p/ABCA1 pathway. by Weixi Wu (11581128)

“…High glucose could decrease circ8411 expression by inhibiting RXRα. GLP-1RAs could potentially reduce cholesterol accumulation and cell pyroptosis by modulating the RXRα/circ8411/miR-23a-5p/ABCA1 axis.…”

Time course of central retinal thickness (CRT) in recurrence and non-recurrence groups. by Yasuyuki Sotani (20114144)

“…These values significantly decreased in the first postoperative year to 2.3 ± 2.6, 0.1 ± 0.3, 0.8 ± 1.6, 0, and 3.1 ± 2.8; in the second year to 2.1 ± 2.8, 0.4 ± 1.0, 0.0, 0.1 ± 0.3, and 2.6 ± 2.8; and in the third year to 2.0 ± 2.2, 0, 0.6 ± 1.7, 0.1 ± 0.3, and 2.8 ± 3.5 (Kruskal–Wallis test, p < 0.001; <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0332941#pone.0332941.g007" target="_blank">Fig 7</a>). …”

Incidence of SARS-CoV-2 infections at the city of Hamburg during the study. by Thorben Fründt (462293)

“…<p>The local incidence of SARS CoV-2 slowly decreases druring the baseline period between 2th April to 30th June and remaind on a low level, when FU-1 was conducted. …”

Categorization of CGI probe loci into five distinct classes of DNA methylation propagation. by Mingxiang Teng (245080)

“…Microarray CpG loci demonstrating a mixture of increased and decreased methylation from generations 1 to 5 were considered “randomly methylate,” while CGI loci showing consistently high methylation (>85% of the maximal microarray fluorescence, regardless of generation, also having ≤15% changes between generations) were designated as “heritably highly methylated.” …”

Treatment with 1,8-cineole reduced infection and cerebral edema in a model of experimental cerebral malaria. by Edgleyson C. dos Santos (12536575)