Data Sheet 1_Global burden of ischemic heart disease attributable to ambient and household PM2.5 exposure: a comprehensive analysis (1990–2021) from socioeconomics perspective.pdf... by Chenran Zhang (4443106)

“…ASMR and ASDR of IHD exhibited a nonlinear association with SDI. PM_2.5 demonstrated positive correlation in regions with SDI < 0.49, and negative correlation in regions with SDI > 0.623. …”

Effects of vinculin and Rab5 knockdown on cellular uptake. by Makoto Hagiwara (513898)

“…<p>(A) siRNAs for vinculin were transfected into HeLa cells, and cell lysates were assayed by western blotting using anti-vinculin, anti-Rab5, and anti-GAPDH antibodies (internal control). …”

Schematic overview of molecular processes altered during disease progression in the SN of PD, identified using transcriptome analysis. by Anke A. Dijkstra (756877)

“…In Braak alpha-synuclein 5 and 6 compared to controls, severe cell loss and alpha-synuclein aggregation is observed [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0128651#pone.0128651.ref041" target="_blank">41</a>]. …”

Kinetics of parasitaemia (asexual stages only, black dots) and gametocytaemia (stages 1–5; black squares) by microscopic observation, represented as a percentage of total erythrocy... by Joël Lelièvre (2196628)

“…From that time onwards, a rapid decrease occurred leading to a parasitaemia (asexual stages) close to zero on day 17. …”

Using a coupled dynamic factor – random forest analysis (DFRFA) to reveal drivers of spatiotemporal heterogeneity in the semi-arid regions of southern Africa - Fig 5 by Jane Southworth (452365)

Using a Bayesian network to understand the importance of coastal storms and undeveloped landscapes for the creation and maintenance of early successional habitat by Sara L. Zeigler (497021)

“…We found that Hurricane Sandy increased piping plover habitat by 9 to 300% at 4 of 5 study sites but that one site saw a decrease in habitat by 27%. …”

Functional validation of a miRNA-34a-TREM2–3’UTR interaction. by Surjyadipta Bhattacharjee (3181674)

“…<p><b>(A)</b> ribonucleotide sequence of the 299 nt TREM2-mRNA-3’-UTR is shown in the 5’-3’ direction; the 22 nt miRNA-34a-TREM2 3’UTR complementarity-interaction region is indicated by a black underline and the 8 nt TREM2-mRNA-3’-UTR seed sequence <b>5’-ACACUGCU-3’</b> is overlaid in yellow; a single arrowhead indicates the 5’ end of a poly A+ tail in the TREM2 mRNA (22 ‘A’ nt shown; the length of this poly A+ tail is variable); TREM2 mRNA sequence derived from NM_018965; TREM2 transcript is the major X1 variant (see also <a href="http://switchdb.switchgeargenomics.com/productinfo/id_801321/" target="_blank">http://switchdb.switchgeargenomics.com/productinfo/id_801321/</a>) (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.g003" target="_blank">Fig 3</a></b>); <b>(B)</b> TREM2-mRNA-3’UTR expression vector luciferase reporter assay (pLightSwitch-3’UTR; Cat#S801178; Switchgear Genomics, Palo Alto CA); in this vector, the entire 299 nucleotide TREM2 3’UTR was ligated into the unique Nhe1-Xho1 site; <b>(C)</b> control C8B4 murine microglial cells, 1 week in culture; phase contrast bright field microscopy 20x; C8B4 cells transfected with the TREM2-mRNA-3’UTR expression vector luciferase reporter were treated exogenously with miRNA-34a, a scrambled control miRNA-34a (miRNA-sc) or control miRNA-183; see references and text for further details [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref018" target="_blank">18</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref019" target="_blank">19</a>]; <b>(D)</b> compared to control, C8B4 cells transfected with a scrambled (<b>sc</b>) control pLightSwitch-3’UTR vector, the TREM2-mRNA-3‘UTR vector exhibited decreased luciferase signal to a mean of 0.16-fold of controls in the presence of miRNA-34a; this same vector exhibited no change in the presence of the control miRNA-34a-sc or miRNA-183; for each experiment (using different batches of MG cells) a control luciferase signal was generated and included separate appropriate controls with each analysis; in addition a control vector β-actin-3’UTR showed no significant effects on the relative luciferase signal yield after treatment with either miRNA-183 or miRNA-34a (data not shown); dashed horizontal line set to 1.0 for ease of comparison; N = 5; *<i>p</i><0.001 (ANOVA). …”

Relative risk of all-cause mortality following SARS-CoV-2 infection in people with preexisting mental disorders. by Tomáš Formánek (19139519)

Relative risk of death with COVID-19 following SARS-CoV-2 infection in people with preexisting mental disorders. by Tomáš Formánek (19139519)

Time-dependent variance of the probability fluxes. by Vladimir A. Andryushchenko (4662829)

Zipf’s and Taylor’s law of species abundance for temperature groups. by Jie Li (15030)

Subfigures 4(a), 4(c), 4(e) and 4(g) present the uptrends duration distributions and subfigures 4(b), 4(d), 4(f) and 4(h) correspond to downtrends duration distributions. by Héctor Raúl Olivares-Sánchez (13014866)

Average grass leaf nitrogen (N), phosphorus (P), increaser (I) or decreaser (D) species and palatability (Palat.code: 0 =  not palatable, 1 =  moderately palatable, 2 =  highly pal... by Anna Christina Treydte (498202)

OIF-inferred species interaction networks and matrices. by Jie Li (15030)

Generation of mice deficient for Dyrk1a in the glutamatergic neurons. by Véronique Brault (160595)

“…Expression of DYRK1A was detected in the cytoplasm of the neurons of the control (Ctrl) and a net decrease of expression was observed in <i>Dyrk1a</i>^<i>C/C</i> neurons as visible in the high-magnification images of the cortex (1), Cornus Ammonis 1(CA1, 2), Cornus Ammonis 3(CA3, 3) and Dentate Gyrus (DG, 4) (white arrows point at neurons with little or no DYRK1A signal). …”

DataSheet_1_A Novel IL3-ETV6 Fusion in Chronic Eosinophilic Leukemia Not Otherwise Specified With t(5; 12) (q31; p13): A Case Report and Literature Review.pdf by Cenzhu Zhao (12804935)

“…Here, we report a case of CEL-NOS with a translocation of t(5;12) (q31; p13) and identify IL3-ETV6 transcription, which has not been identified in hematologic diseases. …”

Data_Sheet_1_Mapping of a Regulatory Site of the Escherichia coli ADP-Glucose Pyrophosphorylase.PDF by Jaina A. Bhayani (7426799)

“…Other potent activator analogs include 1,6-hexanediol bisphosphate (HBP) and pyridoxal 5′-phosphate (PLP). Recently, a crystal structure with FBP bound was reported (PDB ID: 5L6S). …”

Link salience matrices highlighting Pareto links. by Jie Li (15030)

Distribution of PC-level sanitation outcome prevalence in 2016 and 2021 for no-toilet households, private toilets, shared toilets, and unimproved toilets. by Anoop Jain (12095423)

Efficacy and safety of Ixekizumab vs. low-dose IL-2 vs. Colchicine vs. standard of care in the treatment of patients hospitalized with moderate-to-critical COVID-19: A pilot random... by Lívia Pimenta Bonifácio (7502579)

“…The primary outcome was accessed in the “per protocol” population as the proportion of patients with clinical improvement, defined as a decrease greater or equal to two points on the World Health Organization’s (WHO) seven-category ordinal scale by day 28. …”