DataSheet_1_The crosstalk between microbiota and metabolites in AP mice: an analysis based on metagenomics and untargeted metabolomics.docx by Qi Zhou (7408)

Temporal Trend in Young-Onset Type 2 Diabetes - the Macrovascular and Mortality Risk: Study of UK Primary Care Electronic Medical Records by Digsu N. Koye (8881108)

“…The incidence rates of ASCVD and ACM declined in people aged ≥50 years, but did not decrease in people <50 years. …”

Data_Sheet_1_Hybrid Gibbsite Nanoplatelet/Cellulose Nanocrystal Multilayered Coatings for Oxygen Barrier Improvement.PDF by Maud Chemin (5931452)

“…The measurement of the oxygen transmission rate (OTR) at 23°C and 50% RH showed that the oxygen barrier properties of the bare substrates could be significantly improved (e.g., 75% decrease of the OTR) after the deposition of such thin (<100 nm) multilayered hybrid films. …”

Sulfur supply effects on production and mineral nutrition of Tanzania guinea grass under barium levels in nutrient solution by Arnon Afonso de Souza Cardoso (9980536)

“…The combinations with high S and Ba levels resulted in a decrease of 1.7-fold in leaf area compared to combinations with high S without Ba. …”

TNFα stabilizes myocardin mRNA through MEK/MAPK and NF-κB pathways. by Pavneet Singh (657177)

“…<p>(<b>A</b>) VSMCs were serum-starved for 24 h and transcription was blocked using α-amanitin (50 µM). …”

BTK Expression Levels Control DNA Binding Activity and Transcription Factor Function of Ikaros. by Hong Ma (48973)

“…Each siRNA was used at a 50 nM concentration. BTK siRNA (but not Ku80 siRNA) resulted in depletion of BTK protein without a decrease in the amount of IK protein. …”

The effect of IS on H9c2 cardiomyocyte <i>I</i>_<i>K</i> and potassium channel protein Kv2.1 expression. by Wei-Hua Tang (240535)

“…<i>I</i>_{<b><i>k</i></b>} were elicited by 300 ms depolarizing step pulses from -70 to 50 mV at a holding potential of -60 mV. …”

Intranasally applied NPS impacts on basal glutamatergic neurotransmission and plasticity at CA3-CA1 synapses of the VH in C57BL/6N mice. by Julien Dine (369093)

“…B, Intranasally applied NPS reduced paired-pulse facilitation at interstimulus intervals of 25, 50, 100, and 200 ms (Vehicle: open squares: n = 14 slices from 7 mice; NPS: closed squares: n = 11 slices from 5 mice). …”

RAGE blocking and APP inhibition synergistically reduce oxidative stress, apoptosis and rescue sequential gliocentric cell fate change in DS HNPs. by Jie Lu (139953)

“…(B) Graphs show the S100B stimulation for 24 hours dose dependently increase H₂O₂ production and decrease mitochondrial membrane potential which can be blocked by RAGE antibody (1 µg/ml) or dalteparin sodium (1 IU/ml) (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0022126#pone.0022126.s005" target="_blank">Figure S5A</a></b>). …”

Collateral effects are pervasive and vary across parallel evolution experiments in <i>E</i>. <i>faecalis</i>. by Jeff Maltas (1598305)

“…Although the color scale ranges from a 4× decrease to a 4× increase in IC₅₀, it should be noted that both resistance to the selecting drug (diagonal blocks) and collateral effects can be significantly higher. …”

Image2_Hepatoprotective Effects of Glycyrrhetinic Acid on Lithocholic Acid-Induced Cholestatic Liver Injury Through Choleretic and Anti-Inflammatory Mechanisms.TIF by Qian Wang (32718)

“…<p>Cholestasis is a clinical syndrome triggered by the accumulation and aggregation of bile acids by subsequent inflammatory responses. …”

Image1_Hepatoprotective Effects of Glycyrrhetinic Acid on Lithocholic Acid-Induced Cholestatic Liver Injury Through Choleretic and Anti-Inflammatory Mechanisms.TIF by Qian Wang (32718)

“…<p>Cholestasis is a clinical syndrome triggered by the accumulation and aggregation of bile acids by subsequent inflammatory responses. …”

The airway intrinsic BX-C code determines the outcome of <i>hh</i> signaling. by Ryo Matsuda (685668)

“…Note that Salm expression in DT shows a posterior-to-anterior decrease. Upon overexpression of <i>Ubx</i> (G), <i>abdA</i> (H) or <i>AbdB</i> (I), DTa1 becomes negative for Kni and positive for Salm (asterisks). …”

Data_Sheet_4_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Data_Sheet_1_Unequal Impact of COVID-19 on Private and Academic Neurosurgical Workforce: Results of an International Survey.PDF by Sami Ridwan (11510080)

“…</p><p>Conclusion: The lockdown imposed in many countries by the COVID-19 outbreak called for immediate modification of working routine and resulted in a dramatic decrease of elective surgical procedures. …”

Data_Sheet_2_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

Data_Sheet_1_Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2.PDF by Martin Michaelis (23843)

“…Omeprazole 80 μg/mL caused a 10.8-fold (Vero cells) and 47.7-fold (HaCaT cells) decrease of the acyclovir concentrations that reduced HSV-1-induced CPE formation by 50% (IC₅₀). …”

4-Phenyl-1,3-thiazole-2-amines as scaffolds for new antileishmanial agents by Carina Agostinho Rodrigues (5887349)

“…A target fishing study suggested that S-methyl-5-thioadenosine phosphorylase is a potential target to these compounds, which could be explored to enhance activity and decrease the potential toxic side effects. …”

Climatic factors driving vegetation declines in the 2005 and 2010 Amazon droughts by Wenqian Zhao (3937202)

“…The results showed that (i) in the Amazon vegetation greenness responded to precipitation, radiation and temperature, with apparent time lags for most averaging interval periods associated with vegetation index responses of 0–4, 0–9 and 0–6 months, respectively; (ii) on average, the three climatic factors without time lags explained 27.28±21.73% (mean±1 SD) of vegetation index variation in the Amazon basin, and this value increased by 12.22% and reached 39.50±27.85% when time lags were considered; (iii) vegetation greenness in this region in non-drought years was primarily affected by precipitation and shortwave radiation, and these two factors altogether accounted for 93.47% of the total explanation; and (iv) in the common epicenter of the two droughts, pixels with a significant variation in precipitation, radiation and temperature accounted for 36.68%, 40.07% and 10.40%, respectively, of all pixels showing a significant decrease in vegetation index in 2005, and 15.69%, 2.01% and 45.25% in 2010, respectively. …”

Table_1_In vitro investigation of the antiviral activity of propolis and chitosan nanoparticles against the genotype VII Newcastle disease virus.DOCX by Noura Alkhalefa (13387473)

“…The median tissue culture infectious dose (TCID50) assay demonstrated that the nanoparticles have antiviral effects after NDV exposure resulting in significant decrease in viral titer (TCID50) by 2, 2.66, and 2.5 log10 at 62 μg/ml of chitosan, 13 μg/ml of propolis, and 30 μg/ml of the propolis–chitosan mixture, respectively, compared with the control TCID50 value of 4 log10. …”